P22-like viruses

Molecular biology

VIRION

Nonenveloped, head-tail structure. Head is about 60-65 nm in diameter. The tail is non-contractile, has 6 prominent tail spikes. The capsid is icosahedral with a T=7 symmetry.

GENOME

Linear, dsDNA genome of about 41 kb encoding for at least 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its tail fibers.
  2. Injection: viral DNA is injected in host cell periplasm
  3. Transcription and traduction of early genes
  4. Replication of genomic DNA
  5. Transcription and traduction of late genes
  6. Assembly of new virions in host cell cytoplasm
  7. Mature virions are released from the cell by lysis
DB LINKS Nucleotide DB: NCBI
Protein DB: UniProtKB
TAXONOMY Group I: dsDNA viruses
Order: Caudovirales
Family: Podoviridae
Genus: P22-like viruses
SPECIES
Type: Enterobacteria phage P22 (P22)
REFERENCE STRAINS Enterobacteria phage P22 virus
Sequence | Genome | Proteome
HOST Bacteria

Epidemiology

GEOGRAPHY Worldwide
TRANSMISSION Passive diffusion through medium
ANTIVIRAL DRUGS

Matching UniProtKB/Swiss-Prot entries

72 entries grouped by strain

All proteins are shown (view only 64 complete proteome entries)

64 entries

Enterobacteria phage P22 (Bacteriophage P22) reference strain

Select_all Deselect_all  
ABC1_BPP22Anti-RecBCD protein 1 (Protein abc1)
ABC2_BPP22Anti-RecBCD protein 2 (Protein abc2)
ENPP_BPP22Probable endopeptidase (EC 3.4.-.-) (Protein gp15)
ERF_BPP22Essential recombination function protein
GTRA_BPP22Bactoprenol-linked glucose translocase
GTRB_BPP22Bactoprenol glucosyl transferase (EC 2.4.1.-)
LYS_BPP22Lysozyme (EC 3.2.1.17) (Endolysin) (Lysis protein) (Muramidase)

pdb 2ANV  2ANX 

NINB_BPP22Protein ninB
NIND_BPP22Protein ninD
NINE_BPP22Protein ninE
NINF_BPP22Protein ninF
NING_BPP22Protein ninG
NINH_BPP22Protein ninH
NINX_BPP22Putative protein ninX
NINY_BPP22Putative protein ninY
PORTL_BPP22Portal protein (Protein gp1)

pdb 1VT0  3LJ4  3LJ5 

RANT_BPP22Antirepressor protein ant
RARC_BPP22Transcriptional repressor arc

pdb 1ARQ  1ARR  1B28  1BAZ  1BDT  1BDV  1MYK  1MYL  1NLA  1PAR  1QTG  1U9P 

RCRO_BPP22Regulatory protein cro (Antirepressor)

pdb 1RZS 

REGN_BPP22Probable regulatory protein N

pdb 1A4T 

REGQ_BPP22Antitermination protein (Protein gp23)
RMNT_BPP22Regulatory protein mnt

pdb 1MNT  1QEY 

RPC1_BPP22Transcriptional activator protein C1
RPC2_BPP22Repressor protein C2

pdb 1ADR  1QAR  2R1J  3JXB  3JXC  3JXD 

RPC3_BPP22Regulatory protein C3 (CIII)
SIEA_BPP22Superinfection exclusion protein A
SIEB_BPP22Superinfection exclusion protein B
TERL_BPP22Large terminase protein (DNA-packaging protein gp2) (Terminase large subunit)
TERM_BPP22DNA-packaging protein gp3 (Terminase small subunit)
TSPE_BPP22Bifunctional tail protein (Late protein gp9)

pdb 1CLW  1LKT  1QA1  1QA2  1QA3  1QQ1  1QRB  1QRC  1TSP  1TYU  1TYV  1TYW  1TYX  2VFM  2VFN  2VFO  2VFP  2VFQ  2VKY  2VNL  2XC1 

VARF_BPP22Accessory recombination function protein
VEAA_BPP22Eaa protein
VEAC_BPP22Eac protein
VEAD_BPP22Ead protein
VEAE_BPP22Eae protein
VEAF_BPP22Eaf protein
VEAG_BPP22Eag protein
VEAI_BPP22Eai protein
VG04_BPP22Packaged DNA stabilization protein gp4

pdb 1VT0  3LJ4 

VG05_BPP22Coat protein (Protein gp5)

pdb 3IYH  3IYI 

VG07_BPP22DNA transfer protein gp7
VG08_BPP22Scaffolding protein (Protein gp8)

pdb 1GP8  2GP8 

VG10_BPP22Packaged DNA stabilization protein gp10
VG12_BPP22Replicative DNA helicase (EC 3.6.4.12) (Replication protein gp12)
VG14_BPP22Protein gp14
VG16_BPP22DNA transfer protein gp16
VG17_BPP22Superinfection exclusion protein (Protein gp17)
VG18_BPP22DNA replication protein gp18
VG20_BPP22DNA transfer protein gp20
VG26_BPP22Tail needle protein gp26 (Head completion protein) (Packaged DNA stabilization ...

pdb 2POH  3C9I 

VINT_BPP22Integrase
VKIL_BPP22Protein kil
VLY1_BPP22Holin (Lysis protein 13)
VRAL_BPP22Restriction inhibitor protein ral (Antirestriction protein)
VXIS_BPP22Excisionase
Y23K_BPP22Uncharacterized 22.8 kDa protein in gp15-gp3 intergenic region (ORF201)
Y55K_BPP22Uncharacterized 55.3 kDa protein in gtrB 5'region (ORF485)
Y6K4_BPP22Uncharacterized 6.4 kDa protein in sieA-mnt intergenic region (ORF59A)
Y6K6_BPP22Uncharacterized 6.6 kDa protein in eae-abc2 intergenic region (ORF56)
Y7K7_BPP22Uncharacterized 7.7 kDa protein in gp5-gp4 intergenic region (ORF 109) (ORF69)
Y7K8_BPP22Uncharacterized 7.8 kDa protein in ral-gp17 intergenic region (ORF67)
Y8K6_BPP22Uncharacterized 8.6 kDa protein in ral-gp17 intergenic region (ORF78)
Y9K0_BPP22Uncharacterized 9.0 kDa protein in gp15-gp3 intergenic region (ORF80)
YO48_BPP22Uncharacterized 5.8 kDa protein (ORF48)

4 entries

Enterobacteria phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI)

Select_all Deselect_all  
OAC_BPSFVO-acetyl transferase (EC 2.3.1.-) (O-antigen acetylase)
TSPE_BPSFVBifunctional tail protein

pdb 2VBE  2VBK  2VBM 

VINT_BPSFVIntegrase
VXIS_BPSFVProbable excisionase hkaC

2 entries

Enterobacteria phage HK620 (Bacteriophage HK620)

Select_all Deselect_all  
VG07_BPHK6DNA transfer protein gp7
VXIS_BPHK6Probable excisionase hkaC

1 entry

Enterobacteria phage LP7 (Bacteriophage LP7)


TERM_BPLP7DNA-packaging protein gp3 (Terminase small subunit)

1 entry

Enterobacteria phage ST64T (Bacteriophage ST64T)


VG07_BPST6DNA transfer protein gp7
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