Lederbergvirus (taxid:186794)
VIRION
|
Non-enveloped, head-tail structure. The capsid is about 60-65 nm in diameter, with a T=7 laevo icosahedral symmetry . The tail is non-contractile, has 6 prominent tail spikes.
GENOME
Linear, dsDNA genome of about 41 kb encoding for at least 55 genes.
GENE EXPRESSION
REPLICATION
CYTOPLASMIC
- Adsorption: the phage attaches to the target cell through its tail fibers.
- Ejection of the viral DNA into host cell cytoplasm.
- Transcription and translation of early genes.
- Replication of genomic DNA. Transcription and translation of late genes.
- Assembly of an empty procapsid and packaging of the genome.
- Viral tail fibers assembly and viral tail assembly.
- Mature virions are released from the cell by lysis.
Role of the scaffolding protein in P22 procapsid size determination suggested by T = 4 and T = 7 procapsid structures
P. A. Thuman-Commike, B. Greene, J. A. Malinski, J. King, W. Chiu
Biophys. J. January 1998; 74: 559-568
P. A. Thuman-Commike, B. Greene, J. A. Malinski, J. King, W. Chiu
Biophys. J. January 1998; 74: 559-568
The structure of an infectious P22 virion shows the signal for headful DNA packaging
Gabriel C. Lander, Liang Tang, Sherwood R. Casjens, Eddie B. Gilcrease, Peter Prevelige, Anton Poliakov, Clinton S. Potter, Bridget Carragher, John E. Johnson
Science June 23, 2006; 312: 1791-1795
Gabriel C. Lander, Liang Tang, Sherwood R. Casjens, Eddie B. Gilcrease, Peter Prevelige, Anton Poliakov, Clinton S. Potter, Bridget Carragher, John E. Johnson
Science June 23, 2006; 312: 1791-1795
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)76 entries grouped by strain
63 entries
Salmonella phage P22 (Bacteriophage P22) reference strain
2 entries
Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI) reference strain
3 entries
Enterobacteria phage HK620 (Bacteriophage HK620) reference strain
2 entries
Salmonella phage ST64T (Bacteriophage ST64T) reference strain
2 entries
Salmonella phage P22 (Bacteriophage P22)
3 entries
Shigella phage Sf6 (Shigella flexneri bacteriophage VI) (Bacteriophage SfVI)
1 entry