Ostreavirus

VIRION

Enveloped, spherical to pleomorphic, 150-200 nm in diameter, T=16 icoseadral symmetry. Capsid consists of 162 capsomers. Glycoproteins complexes are embeded in the lipid envelope.

GENOME

Monopartite, linear, dsDNA genome of 134 kb. The genome contains terminal and internal reiterated sequences.

GENE EXPRESSION

Each viral transcript usually encodes a single protein and has a promoter/regulatory sequence, a TATA box, a transcription initiation site, a 5’ leader sequence of 30-300 bp (not translated), a 3’ nontranslated sequence of 10-30 bp, and a poly A signal. There are many gene overlaps. There are only few spliced genes. Some of the expressed ORFs are antisense to each other. Some ORFs can be accessed from more than one promoter. There are some non-coding genes.

REPLICATION

NUCLEAR

Lytic replication:

  1. Virus attaches to host receptors through gB, gC, gD and gH .
  2. Fusion with the plasma membrane to release the core and the tegument proteins into the host cytoplasm.
  3. The capsid is transported to the nuclear pore where the viral DNA is released into the nucleus.
  4. Transcription of immediate early genes which promote transcription of early genes.
  5. Transcription of early viral mRNA by host polymerase II, transport into the cytoplasm and translation into early proteins.
  6. Early proteins are involved in replication of the viral DNA and are transported back into the nucleus.
  7. Synthesis of multiple copies of viral DNA by the viral DNA-dependent DNA polymerase.
  8. Transcription of late mRNAs by host polymerase II, transport into the cytoplasm and translation into late proteins.
  9. Late proteins are structural or core proteins and are transported back into the nucleus.
  10. Assembly of the virus and budding through the inner lamella of the nuclear membrane which has been modified by the insertion of herpes glycoproteins, throughout the Golgi and final release at the plasma membrane.

Latent replication : replication of circular viral episome in tandem with the host cell DNA using the host cell replication machinery.

Matching UniProtKB/Swiss-Prot entries

114 entries grouped by strain (browse by keywords)

114 entries

Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

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DPOL_OSHVFDNA polymerase (EC 2.7.7.7)
IAP1_OSHVFPutative apoptosis inhibitor ORF42
IAP2_OSHVFPutative apoptosis inhibitor ORF87
IAP3_OSHVFPutative apoptosis inhibitor ORF99
IAP4_OSHVFPutative apoptosis inhibitor ORF106
PRIM_OSHVFPutative primase (EC 2.7.7.-)
RIR1_OSHVFRibonucleoside-diphosphate reductase large subunit (EC 1.17.4.1)
RIR2_OSHVFRibonucleoside-diphosphate reductase small chain (EC 1.17.4.1)
Y001_OSHVFUncharacterized protein ORF1
Y002_OSHVFUncharacterized protein ORF2
Y003_OSHVFUncharacterized protein ORF3
Y004_OSHVFUncharacterized protein ORF4
Y006_OSHVFUncharacterized protein ORF6
Y008_OSHVFUncharacterized protein ORF8
Y009_OSHVFPutative RING finger protein ORF9
Y010_OSHVFUncharacterized protein ORF10
Y012_OSHVFUncharacterized protein ORF12
Y013_OSHVFUncharacterized protein ORF13
Y014_OSHVFUncharacterized protein ORF14
Y015_OSHVFUncharacterized protein ORF15
Y016_OSHVFUncharacterized protein ORF16
Y017_OSHVFUncharacterized protein ORF17
Y018_OSHVFUncharacterized protein ORF18
Y019_OSHVFUncharacterized protein ORF19
Y021_OSHVFUncharacterized protein ORF21
Y022_OSHVFUncharacterized protein ORF22
Y023_OSHVFUncharacterized protein ORF23
Y024_OSHVFUncharacterized protein ORF24
Y025_OSHVFPutative transmembrane protein ORF25
Y026_OSHVFUncharacterized protein ORF26
Y027_OSHVFUncharacterized protein ORF27
Y028_OSHVFUncharacterized protein ORF28
Y029_OSHVFUncharacterized protein ORF29
Y030_OSHVFUncharacterized protein ORF30
Y031_OSHVFUncharacterized protein ORF31
Y033_OSHVFUncharacterized protein ORF33
Y034_OSHVFUncharacterized protein ORF34
Y035_OSHVFUncharacterized protein ORF35
Y036_OSHVFUncharacterized protein ORF36
Y037_OSHVFUncharacterized protein ORF37
Y038_OSHVFPutative RING finger protein ORF38
Y039_OSHVFUncharacterized protein ORF39
Y040_OSHVFUncharacterized protein ORF40
Y041_OSHVFUncharacterized protein ORF41
Y043_OSHVFUncharacterized protein ORF43
Y044_OSHVFUncharacterized protein ORF44
Y045_OSHVFUncharacterized protein ORF45
Y046_OSHVFUncharacterized protein ORF46
Y047_OSHVFUncharacterized protein ORF47
Y048_OSHVFUncharacterized protein ORF48
Y049_OSHVFUncharacterized protein ORF49
Y052_OSHVFUncharacterized protein ORF52
Y053_OSHVFUncharacterized protein ORF53
Y054_OSHVFUncharacterized protein ORF54
Y055_OSHVFUncharacterized protein ORF55
Y056_OSHVFUncharacterized protein ORF56
Y057_OSHVFPutative transmembrane protein ORF57
Y058_OSHVFUncharacterized protein ORF58
Y059_OSHVFUncharacterized protein ORF59
Y060_OSHVFUncharacterized protein ORF60
Y061_OSHVFUncharacterized protein ORF61
Y064_OSHVFUncharacterized protein ORF64
Y067_OSHVFUncharacterized protein ORF67
Y068_OSHVFPutative transmembrane protein ORF68
Y069_OSHVFUncharacterized protein ORF69
Y070_OSHVFUncharacterized protein ORF70
Y071_OSHVFUncharacterized protein ORF71
Y072_OSHVFUncharacterized protein ORF72
Y074_OSHVFUncharacterized protein ORF74
Y075_OSHVFUncharacterized protein ORF75
Y076_OSHVFUncharacterized protein ORF76
Y077_OSHVFUncharacterized protein ORF77
Y078_OSHVFUncharacterized protein ORF78
Y079_OSHVFUncharacterized protein ORF79
Y080_OSHVFUncharacterized protein ORF80
Y081_OSHVFUncharacterized protein ORF81
Y082_OSHVFUncharacterized protein ORF82
Y083_OSHVFUncharacterized protein ORF83
Y084_OSHVFUncharacterized protein ORF84
Y085_OSHVFUncharacterized protein ORF85
Y086_OSHVFUncharacterized protein ORF86
Y088_OSHVFPutative transmembrane protein ORF88
Y089_OSHVFUncharacterized protein ORF89
Y090_OSHVFUncharacterized protein ORF90
Y091_OSHVFUncharacterized protein ORF91
Y092_OSHVFUncharacterized protein ORF92
Y093_OSHVFUncharacterized protein ORF93
Y094_OSHVFUncharacterized protein ORF94
Y095_OSHVFUncharacterized protein ORF95
Y096_OSHVFPutative RING finger protein ORF96
Y097_OSHVFPutative RING finger protein ORF97
Y098_OSHVFUncharacterized protein ORF98
Y101_OSHVFUncharacterized protein ORF101
Y102_OSHVFUncharacterized protein ORF102
Y103_OSHVFPutative transmembrane protein ORF103
Y104_OSHVFUncharacterized protein ORF104
Y107_OSHVFUncharacterized protein ORF107
Y108_OSHVFUncharacterized protein ORF108
Y109_OSHVFUncharacterized protein ORF109
Y110_OSHVFUncharacterized protein ORF110
Y111_OSHVFPutative transmembrane protein ORF111
Y112_OSHVFUncharacterized protein ORF112
Y113_OSHVFUncharacterized protein ORF113
Y114_OSHVFUncharacterized protein ORF114
Y115_OSHVFUncharacterized protein ORF115
Y116_OSHVFUncharacterized protein ORF116
Y117_OSHVFPutative RING finger protein ORF117
Y118_OSHVFPutative RING finger protein ORF118
Y119_OSHVFUncharacterized protein ORF119
Y120_OSHVFUncharacterized protein ORF120
Y121_OSHVFPutative zinc finger protein ORF121
Y122_OSHVFUncharacterized protein ORF122
Y123_OSHVFUncharacterized protein ORF123
Y124_OSHVFUncharacterized protein ORF124