Tymoviridae (taxid:249184)
VIRION

Non-enveloped, isometric capsid with T=3 icosahedral symmetry, about 30 nm in diameter.
GENOME
Monopartite, linear, C-rich, ssRNA(+) genome of 6-7.5 kb. The 3'-terminus may have a tRNA-like structure or a polyA tract, depending upon the virus.
GENE EXPRESSION
The virion RNA is infectious and serves as both the genome and viral messenger RNA. The virion RNA is infectious and serves as both the genome and viral messenger RNA. The ORF1 encodes a polyprotein whichis expressed by leaky scanning. The capsid protein is translated from a subgenomic RNA.
ENZYMES
- RNA-dependent RNA polymerase [Polyprotein]
- Alpha-type capping [Polyprotein]
- Polyprotein major protease (Peptidase C21) [Polyprotein]
REPLICATION
CYTOPLASMIC
- Virus penetrates into the host cell.
- Uncoating, and release of the viral genomic RNA into the cytoplasm.
- The viral RNA is translated to produce the protein necessary for RNA synthesis (replication and transcription).
- Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
- The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
- The RdRp recognizes an internal subgenomic promoter on the negative-sense RNA to transcribe the 3'co-terminal subgenomic RNA that will generate the capsid protein.
- Assembly of new virus particles.
Host-virus interaction
Modulation of host ubiquitin pathway by virus
Turnip yellow mosaic virus 98K replication protein counteracts degradation of its RNA-dependent RNA polymerase (RdRp) by the host ubiquitin-proteasome system. The viral 98K replication protein mediates deubiquitylation of RdRp leading to its stabilization
.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)28 entries grouped by strain
4 entries
Grapevine fleck virus (isolate Italy/MT48) (GFkV) reference strain
3 entries
Turnip yellow mosaic virus reference strain
2 entries
Maize rayado fino virus (isolate Costa Rica/Guapiles) (MRFV) reference strain
3 entries
Eggplant mosaic virus
3 entries
Erysimum latent virus (ELV)
3 entries
Ononis yellow mosaic virus
3 entries
Turnip yellow mosaic virus (isolate Australia)
2 entries
Kennedya yellow mosaic virus (strain Jervis bay) (KYMV)
2 entries
Turnip yellow mosaic virus (isolate TYMC)
1 entry
Belladonna mottle virus (BMDV)
1 entry
Cacao yellow mosaic virus
1 entry
Physalis mottle virus (PhMV) (Belladonna mottle virus-Iowa)
Andean potato latent virus taxid:73819
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27460 |
Putative movement protein | ma-jd-viral-43062 |
Andean potato mild mosaic virus taxid:1296569
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27461 |
Putative movement protein | ma-jd-viral-43057 |
Asclepias asymptomatic virus taxid:1027880
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27463 |
Movement protein | ma-jd-viral-43061 |
Bee Macula-like virus taxid:1682186
Protein | ModelArchive |
Coat protein | ma-jd-viral-27561 |
p15 | ma-jd-viral-39827 |
Chayote mosaic virus taxid:71030
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27458 |
Overlapping protein | ma-jd-viral-43060 |
Diascia yellow mottle virus taxid:547467
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27462 |
Movement protein MP | ma-jd-viral-43058 |
Fig fleck-associated virus taxid:548908
Protein | ModelArchive |
p50 | ma-jd-viral-41463 |
Grapevine Red Globe virus taxid:103723
Protein | ModelArchive |
Coat protein | ma-jd-viral-27560 |
Grapevine Syrah virus 1 taxid:630199
Protein | ModelArchive |
Putative movement protein | ma-jd-viral-52489 |
Nemesia ring necrosis virus taxid:312009
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27457 |
Putative movement protein | ma-jd-viral-43063 |
Switchgrass mosaic virus taxid:1027869
Protein | ModelArchive |
Movement protein | ma-jd-viral-34434 |
Movement protein | ma-jd-viral-63368 |
Tomato blistering mosaic virus taxid:1010616
Protein | ModelArchive |
Coat protein (Virion protein) | ma-jd-viral-27459 |
Putative movement protein | ma-jd-viral-43059 |
Varroa Tymo-like virus taxid:1682187
Protein | ModelArchive |
Coat protein | ma-jd-viral-27562 |