Maculavirus (taxid:249185)

VIRION

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Non-enveloped, isometric, icosahedral, about 30 nm in diameter.

GENOME

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Linear, C-rich, ssRNA(+) genome of 7.5 kb. The 3' terminus has a poly(A) tract.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The genomic RNA encodes a large replication polyprotein which is cleaved. The capsid protein and two small proteins are translated from two or more 3'-coterminal subgenomic RNAs.

ENZYMES

REPLICATION

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the protein necessary for RNA synthesis (replication and transcription).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. The RdRp recognizes an internal subgenomic promoter on the negative-sense RNA to transcribe the 3'co-terminal subgenomic RNA that will generate the capsid protein.
  7. Assembly of new virus particles.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

4 entries grouped by strain

4 entries

Grapevine fleck virus (isolate Italy/MT48) (GFkV) reference strain

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RDRP_GFKVM RNA replication protein [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); Helicase (EC ...
CAPSD_GFKVM Capsid protein (CP) (Coat protein)
ORF4_GFKVM Uncharacterized protein ORF4
ORF3_GFKVM Uncharacterized protein ORF3