Non enveloped, icosahedral virion with a double capsid structure, about 65-70 nm in diameter. Pentameric turrets sit on the outside of the innermost capsid. The outer capsid has a T=13 icosahedral symmetry, the inner capsid a T=2 icosahedral symmetry.


Segmented linear dsRNA genome. Contains 10 segments coding for 12 proteins. Segments size range from 1.4 to 4.5 kb. Genome total size is about 27-30 kb.


The dsRNA genome is never completely uncoated, to prevent activation of antiviral state by the cell in response to dsRNA. The viral polymerase synthesizes a capped mRNA from each dsRNA segment. This capped mRNA is translocated to the cell cytoplasm where it is translated.



  1. Virus penetrates into the host cell.
  2. Particles are partially uncoated in endolysosomes, but not entirely, and penetrate in the cytoplasm.
  3. Early transcription of the dsRNA genome by viral polymerase occurs inside this sub-viral particle (naked core), so that dsRNA is never exposed to the cytoplasm.
  4. Full-length plus-strand transcripts from each of the dsRNA segments are synthesized. These plus-strand transcripts are used as templates for translation.
  5. Viral proteins and genomic RNAs aggregates in cytoplasmic viral factories.
  6. (+)RNAs are encapsidated in a sub-viral particle, in which they are transcribed to give RNA (-) molecules with which they become base-paired to produce dsRNA genomes.
  7. The capsid is assembled on the sub-viral particle.
  8. Mature virions are released presumably following cell death and associated breakdown of host plasma membrane.

Matching UniProtKB/Swiss-Prot entries

15 entries grouped by strain (browse by keywords)

All proteins are shown (view only 12 complete proteome entries)

12 entries

Fiji disease virus (isolate Sugarcane) (FDV) reference strain

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CAPSD_FDVSPutative major capsid protein
RDRP_FDVSRNA-directed RNA polymerase VP1 (EC
VP10_FDVSPutative outer capsid protein p10
VP3_FDVSPutative structural protein VP3
VP4_FDVSUncharacterized protein VP4
VP5_FDVSUncharacterized protein VP5
VP6_FDVSUncharacterized protein VP6
VP71_FDVSUncharacterized protein VP7-1
VP72_FDVSUncharacterized protein VP7-2
VP8_FDVSMicrotubule-associated protein VP8
VP91_FDVSNon-structural protein P9-1
VP92_FDVSUncharacterized protein VP9-2

2 entries

Maize rough dwarf virus (MRDV)

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VP61_MRDVProbable non-structural 41.0 kDa protein
VP62_MRDVProbable non-structural 36.3 kDa protein

1 entry

Rice black streaked dwarf virus (RBSDV)

VP10_RBSDVProtein S10