Andromedavirus

VIRION


Non-enveloped, head-tail structure. The icosahedral head is about 55 nm in diameter. The tail of about 115 nm in length and 21 nm in width is non-contractile. There is a small baseplate.

GENOME

Linear, dsDNA genome of about 49 kb, containing about 79 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA.
  5. Transcription and translation of late genes
  6. Assembly of an empty procapsid and packaging of the genome.
  7. Viral tail fibers assembly and viral tail assembly.
  8. Mature virions are released from the cell by lysis.