Non enveloped, icosahedral, non-turreted virion with a triple capsid structure, about 60-70 nm in diameter. The intermediate capsid has a T=13 icosahedral symmetry, the inner capsid a T=2 icosahedral symmetry.


Segmented linear dsRNA genome. Contains 12 segments encoding 12 proteins. Segments size range from 862 to 3747 bp, genome total size is about 21 kb (BAV).


The dsRNA genome is never completely uncoated, to prevent activation of antiviral state by the cell in response to dsRNA. The viral polymerase synthesizes a capped mRNA from each dsRNA segment. This capped mRNA is translocated to the cell cytoplasm where it is translated.



  1. Attachement to host receptors probably mediates endocytosis of virus into host cell.
  2. Particles are partially uncoated in endolysosomes, but not entirely, and penetrate in the cytoplasm.
  3. Early transcription of the dsRNA genome by viral polymerase occurs inside this sub-viral particle (naked core), so that dsRNA is never exposed to the cytoplasm.
  4. Full-length plus-strand transcripts from each of the dsRNA segments are synthesized. These plus-strand transcripts are used as templates for translation.
  5. Viral proteins and genomic RNAs aggregates in cytoplasmic viral factories.
  6. (+)RNAs are encapsidated in a sub-viral particle, in which they are transcribed to give RNA (-) molecules with which they become base-paired to produce dsRNA genomes.
  7. The capsid is assembled on the sub-viral particle.
  8. Mature virions are released presumably following cell death and associated breakdown of host plasma membrane.

Matching UniProtKB/Swiss-Prot entries

12 entries grouped by strain (browse by keywords)

12 entries

Banna virus (strain Indonesia/JKT-6423/1980) (BAV) reference strain

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NS1_BAVJKNon-structural protein 1 (NS1)
NS2_BAVJKNon-structural protein 2 (NS2) (VP6)
NS3_BAVJKNon-structural protein 3 (NS3)
NS4_BAVJKNon-structural protein 4 (NS4) (VP11)
NS5_BAVJKNon-structural protein 5 (NS5)
RDRP_BAVJKRNA-directed RNA polymerase VP1 (EC
VP10_BAVJKStructural protein VP10
VP2_BAVJKMajor inner capsid protein VP2
VP3_BAVJKOuter capsid protein VP3
VP4_BAVJKOuter capsid protein VP4
VP8_BAVJKOuter capsid protein VP8
VP9_BAVJKOuter capsid protein VP9 (VP9)