Torradovirus

VIRION

Non-enveloped, about 30 nm in diameter, T=pseudo3 icosahedral capsid. Genome segments are encapsidated separately into two different types of particle similar in size.

GENOME

Segmented, bipartite linear ssRNA(+) genome composed of RNA.1=7.8 kb and RNA-2=5.4 kb. Each genomic segment has a VPg linked to its 5’ end and a 3’ poly(A) tract.

GENE EXPRESSION

The virion RNA is infectious and serves as both genome and mRNA.
RNA-1 and RNA-2 are translated into two polyproteins, which are then processed into functional proteins. RNA-1 encodes proteins necessary for replication, while RNA-2 encodes one or two capsid proteins and product(s) involved in cell-to-cell movement.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Synthesis and proteolytic cleavage of the replicase polyprotein RNA-1.
  4. Replication occurs in viral factories made of membrane vesicles derived from the ER. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Assembly of new virus particles.
  7. Movement protein allows cell-to-cell movement.

Matching UniProtKB/Swiss-Prot entries

3 entries grouped by strain (browse by keywords)

3 entries

Tomato torrado virus (isolate Solanum lycopersicum/Spain/PRIToTV0301/-) (ToTV) reference strain

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ORF1_TOTVUncharacterized protein ORF1
POL1_TOTVRNA1 polyprotein
POL2_TOTVRNA2 polyprotein