Cytorhabdovirus (taxid:11305)

VIRION

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Enveloped, bullet shaped. 180 nm long and 75 nm wide. Certain plant rhabdoviruses are bacilliform in shape and almost twice the length.

GENOME

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Negative-stranded RNA linear genome, about 13 kb in size. Encodes for six (LNYV) to nine (NCMV) proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

ENZYMES

REPLICATION

IN PLANT:CYTOPLASMIC

  1. Virus penetrates into the cell by effraction or plasmodesmata transport.
  2. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  3. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  4. The ribonucleocapsid can penetrate in neighboring plant cells through plasmodesmata transport
  5. Alternatively the ribonucleocapsid can binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

IN INSECT:CYTOPLASMIC

  1. Attachment of the viral G glycoproteins to host receptors.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
  3. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

Host-virus interaction

Movement through plasmodesmata

Viral movement protein

Viral movement protein presumably interacts with host plasmodesmata to allow tubule guided movement of viral genomic material from cell to cell without budding.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

14 entries grouped by strain

8 entries

Northern cereal mosaic virus (NCMV) reference strain

Select_allDeselect_all
GLYCO_NCMV Glycoprotein
MATRX_NCMV Matrix protein
PHOSP_NCMV Phosphoprotein (Protein P) (Protein M1)
NCAP_NCMV Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
VP6_NCMV Protein 6
VP5_NCMV Protein 5
VP4_NCMV Protein 4
VP3_NCMV Protein 3

6 entries

Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain

Select_allDeselect_all
L_LNYV3 RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase) ...
NCAP_LNYV3 Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
GLYCO_LNYV3 Glycoprotein
VP4A_LNYV3 Phosphoprotein (Protein P) (Protein 4a)
MATRX_LNYV3 Matrix protein
MVP_LNYV3 Probable movement protein 4b (MP) (Cell-to-cell transport protein) (Protein 4b)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Alfalfa dwarf virus taxid:998864

Protein ModelArchive
Glycoprotein ma-jd-viral-40212
Matrix protein ma-jd-viral-11680
Nucleoprotein (NP) (Protein N) (Nucleocapsid protein) ma-jd-viral-15218
Phosphoprotein ma-jd-viral-07644
Protein 6 ma-jd-viral-42508
Putative movement protein ma-jd-viral-27465

Lettuce necrotic yellows virus (isolate 318) taxid:928304

Protein ModelArchive
Glycoprotein ma-jd-viral-40215
Matrix protein ma-jd-viral-11602
Nucleoprotein (NP) (Nucleocapsid protein) (Protein N) ma-jd-viral-15226
Phosphoprotein (Protein P) (Protein 4a) ma-jd-viral-07646
Probable movement protein 4b (MP) (Cell-to-cell transport protein) (Protein 4b) ma-jd-viral-28026

Lettuce yellow mottle virus taxid:471285

Protein ModelArchive
G protein ma-jd-viral-40216
M protein ma-jd-viral-11600
Nucleoprotein (NP) (Protein N) (Nucleocapsid protein) ma-jd-viral-15223
P protein ma-jd-viral-07642
Protein 3 ma-jd-viral-28021

Persimmon virus A taxid:1211480

Protein ModelArchive
Glycoprotein ma-jd-viral-40221
Matrix protein ma-jd-viral-11672
Movement protein BC1 (Movement protein BL1) ma-jd-viral-27109
Nucleoprotein (NP) (Protein N) (Nucleocapsid protein) ma-jd-viral-15216
Phosphoprotein ma-jd-viral-07643

Wuhan Insect virus 4 taxid:1608109

Protein ModelArchive
4b protein ma-jd-viral-28024
Glycoprotein ma-jd-viral-40213
Nucleoprotein (NP) (Protein N) (Nucleocapsid protein) ma-jd-viral-15217
Phosphoprotein ma-jd-viral-07638
Putative matrix protein ma-jd-viral-11738

Wuhan Insect virus 5 taxid:1608110

Protein ModelArchive
4b protein ma-jd-viral-27110
Glycoprotein ma-jd-viral-40219
Matrix protein ma-jd-viral-11588
Nucleoprotein (NP) (Protein N) (Nucleocapsid protein) ma-jd-viral-15222
Phosphoprotein ma-jd-viral-07639

Wuhan Insect virus 6 taxid:1608111

Protein ModelArchive
4b protein ma-jd-viral-27467
Glycoprotein ma-jd-viral-40220
Matrix protein ma-jd-viral-11681
Nucleoprotein (NP) (Protein N) (Nucleocapsid protein) ma-jd-viral-15228
Phosphoprotein ma-jd-viral-07640