Nucleorhabdovirus

VIRION

Enveloped, bullet shaped. 180 nm long and 75 nm wide. Certain plant rhabdoviruses are bacilliform in shape and almost twice the length.

GENOME

Negative-stranded RNA linear genome, about 11-15 kb in size. Encodes for 5 to six proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

REPLICATION

NUCLEAR

  1. Attachment of the viral G glycoproteins to host receptors
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
  3. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid can penetrate in neighboring cells through plasmodesmata transport
  6. The ribonucleocapsid binds to the matrix protein and the budding of particles occurs at a cell membrane, releasing new virions.

Host-virus interaction

Movement through plasmodesmata

Viral movement protein 3of RYSV presumably interacts with host plasmodesmata to allow tubule guided movement of viral genomic material from cell to cell without budding.

Matching UniProtKB/Swiss-Prot entries

25 entries grouped by strain (browse by keywords)

7 entries

Rice yellow stunt virus (RYSV) (Rice transitory yellowing virus) reference strain

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GLYCO_RYSVGlycoprotein
L_RYSVRNA-directed RNA polymerase L (Protein L) (Large structural protein) ...
MATRX_RYSVMatrix protein
MVP_RYSVMovement protein (MP) (Cell-to-cell transport protein) (Protein 3)
NCAP_RYSVNucleoprotein (NP) (Nucleocapsid protein) (Protein N)
PHOSP_RYSVPhosphoprotein (Protein P) (Protein M1)
VP6_RYSVProtein 6

6 entries

Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV) reference strain

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GLYCO_MMVRGlycoprotein
L_MMVRRNA-directed RNA polymerase L (Protein L) (Large structural protein) ...
MATRX_MMVRMatrix protein
MVP_MMVRPutative movement protein 3 (MP) (Cell-to-cell transport protein) (Protein 3)
NCAP_MMVRNucleoprotein (NP) (Nucleocapsid protein) (Protein N)
PHOSP_MMVRPhosphoprotein (Protein P) (Protein M1)

6 entries

Sonchus yellow net virus (SYNV) reference strain

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GLYCO_SYNVSpike glycoprotein
L_SYNVRNA-directed RNA polymerase L (Protein L) (Large structural protein) ...
MATRX_SYNVMatrix protein (M2 protein)
MVP_SYNVMovement protein (MP) (Cell-to-cell transport protein) (Protein Sc4)
NCAP_SYNVNucleoprotein (NP) (Nucleocapsid protein) (Protein N)
PHOSP_SYNVPhosphoprotein (Protein P) (Protein M1)

6 entries

Taro vein chlorosis virus (TAVCV) reference strain

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GLYCO_TAVCVGlycoprotein
L_TAVCVRNA-directed RNA polymerase L (Protein L) (Large structural protein) ...
MATRX_TAVCVMatrix protein
MVP_TAVCVMovement protein (MP) (Cell-to-cell transport protein) (Protein 3)
NCAP_TAVCVNucleoprotein (NP) (Nucleocapsid protein) (Protein N)
PHOSP_TAVCVPhosphoprotein (Protein P) (Protein M1)