DNA-directed RNA polymerase (kw:KW-0240)

Virally encoded protein (EC 2.7.7.6) which synthesizes RNA using DNA as a template. This enzyme activity might be necessary for the viral genome transcription of some viruses.

Links Uniprot Keyword: KW-0240

GO ontology: GO:0000428
Virus All these viruses have been shown to encode a viral DNA-directed RNA polymerase:



Ascoviridae

Asfarviridae

Baculoviridae

Possibly Myoviridae

Phycodnaviridae

Podoviridae

Poxviridae

Possibly Siphoviridae

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

133 entries grouped by strain

8 entries

Fowlpox virus (strain NVSL) (FPV) reference strain

Select_allDeselect_all
RP18_FOWPN DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RP19_FOWPN DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RPO5_FOWPN DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP22_FOWPN DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)
RP35_FOWPN DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP132_FOWPN DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)
RP147_FOWPN DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP07_FOWPN DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

8 entries

Monkeypox virus reference strain

Select_allDeselect_all
RP30_MONPV DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP19_MONPV DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RP07_MONPV DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP147_MONPV DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP18_MONPV DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RP132_MONPV DNA-directed RNA polymerase (EC 2.7.7.6)
RP35_MONPV DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP22_MONPV DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)

3 entries

Vaccinia virus (strain Copenhagen) (VACV) reference strain

Select_allDeselect_all
RP30_VACCC DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP132_VACCC DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

pdb 8P0J; 8P0K; 8P0N

RP147_VACCC DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)

pdb 8P0J; 8P0K; 8P0N

8 entries

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

Select_allDeselect_all
RP30_VACCW DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)

pdb 8C8H

RP18_VACCW DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)

pdb 8C8H

RP147_VACCW DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)

pdb 8C8H

RP35_VACCW DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)

pdb 8C8H

RP07_VACCW DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

pdb 8C8H

RP22_VACCW DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)

pdb 6RIE; 8C8H

RP19_VACCW DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)

pdb 8C8H

RP132_VACCW DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

pdb 6RIE; 8C8H

8 entries

Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain

Select_allDeselect_all
RP30_VAR67 DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)
RP19_VAR67 DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RP147_VAR67 DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP132_VAR67 DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
RP07_VAR67 DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP18_VAR67 DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RP22_VAR67 DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)
RP35_VAR67 DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)

7 entries

African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

Select_allDeselect_all
RPB1_ASFB7 DNA-directed RNA polymerase RPB1 homolog (RPB1 homolog) (EC 2.7.7.6)

pdb 8Q3B; 8Q3K

RPB2_ASFB7 DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6)

pdb 8Q3B; 8Q3K

RPB6_ASFB7 DNA-directed RNA polymerase RPB6 homolog (RPB6 homolog)

pdb 8Q3B; 8Q3K

RPB10_ASFB7 DNA-directed RNA polymerase RPB10 homolog (RPB10 homolog)

pdb 8Q3B; 8Q3K

RPB5_ASFB7 DNA-directed RNA polymerase RPB5 homolog (RPB5 homolog)

pdb 8Q3B; 8Q3K

RPB3_ASFB7 DNA-directed RNA polymerase RPB3-11 homolog (RPB3-11 homolog)

pdb 8Q3B; 8Q3K

RPB7_ASFB7 DNA-directed RNA polymerase RPB7 homolog (RPB7 homolog)

pdb 8Q3B; 8Q3K

6 entries

Acanthamoeba polyphaga mimivirus (APMV) reference strain

Select_allDeselect_all
RPO2_MIMIV DNA-directed RNA polymerase subunit 2 (EC 2.7.7.6)
RPO5_MIMIV DNA-directed RNA polymerase subunit 5 (EC 2.7.7.6)
RPO6_MIMIV DNA-directed RNA polymerase subunit 6 (EC 2.7.7.6)
YR470_MIMIV Putative DNA directed RNA polymerase subunit R470 (EC 2.7.7.6)
YL376_MIMIV Putative DNA-directed RNA polymerase subunit L376 (EC 2.7.7.6)
RPO1_MIMIV DNA-directed RNA polymerase subunit 1 (EC 2.7.7.6)

4 entries

Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) reference strain

Select_allDeselect_all
RPB1_IIV6 Probable DNA-directed RNA polymerase II subunit RPB1 homolog (EC 2.7.7.6)
454R_IIV6 Putative DNA-directed RNA polymerase subunit 454R
RPB2_IIV6 Probable DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)
343L_IIV6 Probable DNA-directed RNA polymerase subunit 343L (EC 2.7.7.6)

1 entry

Variola virus reference strain

RP132_VARV DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)

2 entries

Frog virus 3 (isolate Goorha) (FV-3) reference strain

Select_allDeselect_all
RPB2_FRG3G Putative DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)
RPB1_FRG3G Putative DNA-directed RNA polymerase 008R (EC 2.7.7.6)

2 entries

Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) reference strain

Select_allDeselect_all
RPB1_IIV3 Probable DNA-directed RNA polymerase II subunit RPB1 homolog (EC 2.7.7.6)
RPB2_IIV3 Probable DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)

2 entries

Myxoma virus (strain Lausanne) (MYXV) reference strain

Select_allDeselect_all
RP22_MYXVL DNA-directed RNA polymerase 21 kDa subunit (EC 2.7.7.6)
RP07_MYXVL DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

1 entry

Autographa californica nuclear polyhedrosis virus (AcMNPV) reference strain

LEF8_NPVAC Probable DNA-directed RNA polymerase catalytic subunit (EC 2.7.7.6) (Late expression factor 8)

1 entry

Bacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta) reference strain

YONO_BPSPB DNA-directed RNA polymerase YonO (EC 2.7.7.6) (DNA-dependent RNA polymerase YonO)

1 entry

Camelpox virus (strain CMS) reference strain

RP132_CAMPS DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Enterobacteria phage N4 (Bacteriophage N4) reference strain

RPOLV_BPN4 Virion DNA-directed RNA polymerase (vRNAP) (EC 2.7.7.6) (Gene product 50) (gp50)

pdb 2PO4; 3C2P; 3C3L; 3C46; 3Q0A; 3Q22; 3Q23; 3Q24; 4FF1; 4FF2; 4FF3; 4FF4

1 entry

Enterobacteria phage P4 (Bacteriophage P4) reference strain

PRIM_BPP4 Putative P4-specific DNA primase (EC 2.7.7.-) (EC 3.6.4.12)

pdb 1KA8

1 entry

Escherichia phage T7 (Bacteriophage T7) reference strain

RPOL_BPT7 T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)

pdb 1ARO; 1CEZ; 1H38; 1MSW; 1QLN; 1S0V; 1S76; 1S77; 2PI4; 2PI5; 3E2E; 3E3J; 4RNP; 8DH0; 8DH1; 8DH2; 8DH3; 8DH4; 8DH5

1 entry

Molluscum contagiosum virus subtype 1 (MOCV) (MCVI) reference strain

RP07_MCV1 DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

1 entry

Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) reference strain

RPOB_NPVOP Probable DNA-directed RNA polymerase subunit beta (EC 2.7.7.6) (Late expression factor 8)

1 entry

Pseudomonas phage phiKMV reference strain

RPOL_BPKMV DNA-directed RNA polymerase (EC 2.7.7.6)

1 entry

Rabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza)) reference strain

RP07_RFVKA DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

8 entries

African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)

Select_allDeselect_all
RPB2_ASFM2 DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6)
RPB6_ASFM2 DNA-directed RNA polymerase RPB6 homolog (RPB6 homolog)
RPB1_ASFM2 DNA-directed RNA polymerase RPB1 homolog (RPB1 homolog) (EC 2.7.7.6)
RPB10_ASFM2 DNA-directed RNA polymerase RPB10 homolog (RPB10 homolog)
RPB9_ASFM2 DNA-directed RNA polymerase RPB9 homolog (RPB9 homolog)
RPB7_ASFM2 DNA-directed RNA polymerase RPB7 homolog (RPB7 homolog)
RPB5_ASFM2 DNA-directed RNA polymerase RPB5 homolog (RPB5 homolog)
RPB3_ASFM2 DNA-directed RNA polymerase RPB3-11 homolog (RPB3-11 homolog)

8 entries

African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV)

Select_allDeselect_all
RPB2_ASFP4 DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6)
RPB10_ASFP4 DNA-directed RNA polymerase RPB10 homolog (RPB10 homolog)
RPB1_ASFP4 DNA-directed RNA polymerase RPB1 homolog (RPB1 homolog) (EC 2.7.7.6)
RPB5_ASFP4 DNA-directed RNA polymerase RPB5 homolog (RPB5 homolog)
RPB6_ASFP4 DNA-directed RNA polymerase RPB6 homolog (RPB6 homolog)
RPB3_ASFP4 DNA-directed RNA polymerase RPB3-11 homolog (RPB3-11 homolog)
RPB9_ASFP4 DNA-directed RNA polymerase RPB9 homolog (RPB9 homolog)
RPB7_ASFP4 DNA-directed RNA polymerase RPB7 homolog (RPB7 homolog)

5 entries

Vaccinia virus (strain Copenhagen) (VACV)

Select_allDeselect_all
RP07_VACCC DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

pdb 8P0J; 8P0K; 8P0N

RP19_VACCC DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)
RP18_VACCC DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)
RP35_VACCC DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)

pdb 8P0J; 8P0K; 8P0N

RP22_VACCC DNA-directed RNA polymerase 22 kDa subunit (EC 2.7.7.6)

pdb 8P0J; 8P0K; 8P0N

7 entries

African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)

Select_allDeselect_all
RPB2_ASFK5 DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6)
RPB6_ASFK5 DNA-directed RNA polymerase subunit 6 homolog (RPB6 homolog)
RPB10_ASFK5 DNA-directed RNA polymerase RPB10 homolog (RPB10 homolog)
RPB1_ASFK5 DNA-directed RNA polymerase RPB1 homolog (EC 2.7.7.6)
RPB5_ASFK5 DNA-directed RNA polymerase RPB5 homolog (RPB5 homolog)
RPB3_ASFK5 DNA-directed RNA polymerase RPB3-11 homolog (RPB3-11 homolog)
RPB7_ASFK5 DNA-directed RNA polymerase RPB7 homolog (RPB7 homolog)

7 entries

African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)

Select_allDeselect_all
RPB2_ASFWA DNA-directed RNA polymerase RPB2 homolog (RPB2 homolog) (EC 2.7.7.6)
RPB10_ASFWA DNA-directed RNA polymerase RPB10 homolog (RPB10 homolog)
RPB1_ASFWA DNA-directed RNA polymerase RPB1 homolog (RPB1 homolog) (EC 2.7.7.6)
RPB5_ASFWA DNA-directed RNA polymerase RPB5 homolog (RPB5 homolog)
RPB6_ASFWA DNA-directed RNA polymerase subunit 6 homolog (RPB6 homolog)
RPB3_ASFWA DNA-directed RNA polymerase RPB3-11 homolog (RPB3-11 homolog)
RPB7_ASFWA DNA-directed RNA polymerase RPB7 homolog (RPB7 homolog)

7 entries

Vaccinia virus (strain Ankara) (VACV)

Select_allDeselect_all
RP30_VACCA DNA-directed RNA polymerase 30 kDa polypeptide (EC 2.7.7.6)

pdb 6RIE

RP147_VACCA DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)

pdb 6RIE

RP132_VACCA DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
RP35_VACCA DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)

pdb 6RIE

RP07_VACCA DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

pdb 6RIE

RP19_VACCA DNA-directed RNA polymerase 19 kDa subunit (EC 2.7.7.6)

pdb 6RIE

RP18_VACCA DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)

pdb 6RIE

3 entries

Variola virus

Select_allDeselect_all
RP147_VARV DNA-directed RNA polymerase 147 kDa polypeptide (EC 2.7.7.6)
RP07_VARV DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)
RP18_VARV DNA-directed RNA polymerase 18 kDa subunit (EC 2.7.7.6)

3 entries

Vaccinia virus (strain Tian Tan) (VACV)

Select_allDeselect_all
RP35_VACCT DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP132_VACCT DNA-directed RNA polymerase 133 kDa polypeptide (EC 2.7.7.6)
RP07_VACCT DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)

2 entries

Enterobacteria phage T3 (Bacteriophage T3)

Select_allDeselect_all
HELIC_BPT3 DNA helicase/primase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)
RPOL_BPT3 DNA-directed RNA polymerase (EC 2.7.7.6)

2 entries

Rabbitpox virus (strain Utrecht) (RPV)

Select_allDeselect_all
RP35_RABPU DNA-directed RNA polymerase 35 kDa subunit (EC 2.7.7.6)
RP132_RABPU DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Bacillus phage B103 (Bacteriophage B103)

VG4_BPB03 Late genes activator (Early protein GP4)

1 entry

Bacillus phage Nf (Bacteriophage Nf)

VG4_BPNF Late genes activator (Early protein GP4) (GPF)

1 entry

Camelpox virus (strain M-96)

RP132_CAMPM DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Cowpox virus (strain Brighton Red) (CPV)

RP132_CWPXB DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Cowpox virus (strain GRI-90 / Grishak) (CPV)

RP132_CWPXG DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)

RP132_ECTVM DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Enterobacteria phage K11 (Bacteriophage K11)

RPOL_BPK11 DNA-directed RNA polymerase (EC 2.7.7.6)

1 entry

Enterobacteria phage SP6 (Bacteriophage SP6)

RPOL_BPSP6 DNA-directed RNA polymerase (EC 2.7.7.6)

1 entry

Monkeypox virus (strain Zaire-96-I-16) (MPX)

RP132_MONPZ DNA-directed RNA polymerase 132 kDa polypeptide (EC 2.7.7.6)

1 entry

Myxoma virus (strain Uriarra) (MYXV)

RP22_MYXVU DNA-directed RNA polymerase 21 kDa subunit (EC 2.7.7.6)

1 entry

Spodoptera littoralis nuclear polyhedrosis virus (SlNPV)

RPOB_NPVSL Probable DNA-directed RNA polymerase subunit beta (EC 2.7.7.6) (Late expression factor 8)

1 entry

Yaba-like disease virus (YLDV)

RP07_YLDV DNA-directed RNA polymerase 7 kDa subunit (EC 2.7.7.6)