Soymovirus

VIRION

image

Non enveloped, large (50 nm diameter) icosahedral particles composed of 420 subunits with a T=7 symmetry. The virion shell is multi-layered. It has not been described whether handedness of capsid is laevo or dextro, here the pictures dsplays a laevo form.

GENOME

image

Circular double stranded DNA of about 8000 base pairs with discontinuities in both strands: one in the transcribed strand and one to three in the non-transcribed strand. Codes for 8 proteins.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC NUCLEAR

  1. Attachment of the viral proteins to host receptors mediates its entry into the host cell.
  2. The viral dsDNA is released into the nucleus where it is transcribed by host RNA polymerase II
  3. RNA translation produces viral proteins.
  4. Genomic RNA is retrotranscribed in the cytoplasm into new dsDNA genomes
  5. Genomes are encapsidated with capsid protein, releasing new virions.