Sobemovirus (taxid:12137)

VIRION

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Non enveloped virion, about 30 nm in diameter with a T=3 icosahedral symmetry (180 protein subunits).
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GENOME

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Monopartite, linear, ssRNA(+) genome of 4 kb. The 5' terminus has a genome-linked protein (VPg). The 3' terminus is not polyadenylated. Some sobemoviruses encapsidate a circular viroid-like satellite RNA (220-390nt).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. ORF1 and ORF2 are translated via leaky scanning . ORF2 is a polyprotein which is presumably cleaved into a serine-protease, a VPg and a RdRp protein. The viral serine protease is responsible for all the cleavages. ORF3 is translated via a -1 ribosomal frameshifting. Replication produces a subgenomic RNA which encodes for the capsid protein (ORF4).
Cocksfoot mottle sobemovirus polyprotein is encoded by two different ORFs, the second one is translated via a -1 ribosomal frameshifting. The equivalent of ORF3 is not present.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce replication proteins, ORF2 polyprotein is processed by the viral protease.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the subgenomic RNA encoding for ORF4 capsid protein.
  7. Virus assembly.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Cocksfoot mottle virus P1 protein acts as a suppressor of RNA silencing .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

12 entries grouped by strain

4 entries

Cocksfoot mottle virus (isolate Dactylis glomerata/Norway/CfMV-NO/1995) (CfMV) reference strain

Select_allDeselect_all
RDRP_CFMVN Replicase polyprotein P2AB [Cleaved into: N-terminal protein; Serine protease (EC 3.4.21.-); VPg; ...
P2A_CFMVN Polyprotein P2A [Cleaved into: N-terminal protein; Serine protease (EC 3.4.21.-); VPg; Putative ...
CAPSD_CFMVN Capsid protein (CP) (Coat protein) (Protein P4)
MVP_CFMVN Movement protein P1 (Cell-to-cell transport protein)

4 entries

Southern bean mosaic virus (isolate Bean/United States/Arkansas) (SBMV) reference strain

Select_allDeselect_all
RDRP_SBMVA Replicase polyprotein P2AB [Cleaved into: N-terminal protein; Serine protease (EC 3.4.21.-); VPg; ...
P2A_SBMVA Polyprotein P2A [Cleaved into: N-terminal protein; Serine protease (EC 3.4.21.-); VPg; Putative ...
CAPSD_SBMVA Capsid protein (CP) (Coat protein)
MVP_SBMVA Movement protein P1 (Cell-to-cell transport protein)

4 entries

Southern cowpea mosaic virus (SCPMV) (Southern bean mosaic virus (strain cowpea)) reference strain

Select_allDeselect_all
CAPSD_SCPMV Capsid protein (Coat protein)
RDRP_SCPMV Replicase polyprotein P2AB [Cleaved into: N-terminal protein; Serine protease (EC 3.4.21.-); VPg; ...
P2A_SCPMV Polyprotein P2A [Cleaved into: N-terminal protein; Serine protease (EC 3.4.21.-); VPg; Putative ...
MVP_SCPMV Movement protein P1 (Cell-to-cell transport protein)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Artemisia virus A taxid:1133751

Protein ModelArchive
Capsid protein ma-jd-viral-28782
ORF1 ma-jd-viral-30602
ORF2a ma-jd-viral-60962

Cymbidium chlorotic mosaic virus taxid:1602124

Protein ModelArchive
Capsid protein ma-jd-viral-28788
Polyprotein P2a ma-jd-viral-17510
Polyprotein P2a-P2b ma-jd-viral-19440
p1 ma-jd-viral-57830

Imperata yellow mottle virus taxid:524023

Protein ModelArchive
Capsid protein ma-jd-viral-28787
Protease and VPg ma-jd-viral-42470
p1 ma-jd-viral-51691

Lucerne transient streak virus taxid:12470

Protein ModelArchive
Capsid protein ma-jd-viral-28795
Polyprotein P2a ma-jd-viral-44271
Polyprotein P2a ma-jd-viral-60884
Polyprotein P2a2b ma-jd-viral-18930
Polyprotein P2a2b ma-jd-viral-44266
p1 ma-jd-viral-59409

Papaya lethal yellowing virus taxid:685899

Protein ModelArchive
Capsid protein ma-jd-viral-28784
Putative suppressor of RNA silencing ma-jd-viral-55989
Serine protease ma-jd-viral-44268
Serine protease ma-jd-viral-60886

Rottboellia yellow mottle virus taxid:1432563

Protein ModelArchive
Capsid protein ma-jd-viral-28792
Polyprotein P2a ma-jd-viral-17511
Polyprotein P2a2b ma-jd-viral-19437
Putative Px ma-jd-viral-40307
Putative RNA silencing suppressor ma-jd-viral-63850

Ryegrass mottle virus taxid:119910

Protein ModelArchive
Capsid protein ma-jd-viral-28779
Polyprotein ma-jd-viral-60961
Polyprotein (p2a2b) ma-jd-viral-18939
Polyprotein (p2a2b) ma-jd-viral-44276
Px ma-jd-viral-40306
p1 ma-jd-viral-65692

Solanum nodiflorum mottle virus taxid:12471

Protein ModelArchive
Capsid protein ma-jd-viral-28794
Polyprotein P2a ma-jd-viral-17513
Polyprotein P2a2b ma-jd-viral-19457
Putative RNA silencing suppressor ma-jd-viral-43049

Sowbane mosaic virus taxid:378833

Protein ModelArchive
Capsid protein ma-jd-viral-28790
p1 protein ma-jd-viral-60610
p2a protein ma-jd-viral-55064
p2a-P2b fusion protein ma-jd-viral-18928
p2a-P2b fusion protein ma-jd-viral-44273

Soybean yellow common mosaic virus taxid:1080798

Protein ModelArchive
Capsid protein ma-jd-viral-28778
Putative movement protein ma-jd-viral-56578

Subterranean clover mottle virus taxid:12472

Protein ModelArchive
Capsid protein ma-jd-viral-28796
ORF1 ma-jd-viral-44531

Turnip rosette virus taxid:218923

Protein ModelArchive
Capsid protein ma-jd-viral-28791
Polyprotein P2a ma-jd-viral-17512
Polyprotein P2ab ma-jd-viral-19458
p1 ma-jd-viral-29937

Velvet tobacco mottle virus taxid:12473

Protein ModelArchive
Capsid protein ma-jd-viral-28793
p1 ma-jd-viral-36759
p2a ma-jd-viral-33257