Tymovirus (taxid:12148)



Non-enveloped, isometric capsid with T=3 icosahedral symmetry, about 30 nm in diameter.



Linear, C-rich, ssRNA(+) genome of 6.3 kb. The 3'-terminus has a tRNA-like structure.


The virion RNA is infectious and serves as both the genome and viral messenger RNA. The ORF1 encodes a polyprotein whichis expressed by leaky scanning. The capsid protein is translated from a subgenomic RNA.




  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the protein necessary for RNA synthesis (replication and transcription).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. The RdRp recognizes an internal subgenomic promoter on the negative-sense RNA to transcribe the 3'co-terminal subgenomic RNA that will generate the capsid protein.
  7. Assembly of new virus particles.
  8. Movement protein allows cell-to-cell movement.

Host-virus interaction

Modulation of host ubiquitin pathway by virus

Turnip yellow mosaic virus 98K replication protein counteracts degradation of the viral RNA-dependent RNA polymerase (RdRp) by host ubiquitin-proteasome system. The 98K replication protein mediates deubiquitylation of RdRp leading to its stabilization .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

22 entries grouped by strain

3 entries

Turnip yellow mosaic virus reference strain

POLR_TYMV RNA replicase polyprotein (206 kDa polyprotein) (206K) [Cleaved into: ...
COAT_TYMV Coat protein (Virion protein)
P69_TYMV 69 kDa protein (p69)

3 entries

Eggplant mosaic virus

POLR_EPMV RNA replicase polyprotein (EC
COAT_EPMV Coat protein (Virion protein)
P69_EPMV 70 kDa protein

3 entries

Erysimum latent virus (ELV)

POLR_ELV RNA replicase polyprotein (EC
COAT_ELV Coat protein (Virion protein)
Y48K_ELV Uncharacterized 48 kDa protein

3 entries

Ononis yellow mosaic virus

POLR_OYMV RNA replicase polyprotein (EC
COAT_OYMV Coat protein (Virion protein)
P69_OYMV 66 kDa protein

3 entries

Turnip yellow mosaic virus (isolate Australia)

POLR_TYMVA RNA replicase polyprotein (206 kDa polyprotein) (206K) [Cleaved into: ...
COAT_TYMVA Coat protein (Virion protein)
P69_TYMVA 69 kDa protein (p69)

2 entries

Kennedya yellow mosaic virus (strain Jervis bay) (KYMV)

POLR_KYMVJ RNA replicase polyprotein (EC
COAT_KYMVJ Coat protein (Virion protein)

2 entries

Turnip yellow mosaic virus (isolate TYMC)

POLR_TYMVC RNA replicase polyprotein (206 kDa polyprotein) (206K) [Cleaved into: ...
P69_TYMVC 69 kDa protein (p69)

1 entry

Belladonna mottle virus (BMDV)

COAT_BMDV Coat protein (Virion protein)

1 entry

Cacao yellow mosaic virus

COAT_CAYMV Coat protein (Virion protein)

1 entry

Physalis mottle virus (PhMV) (Belladonna mottle virus-Iowa)

COAT_PHMV Coat protein (Virion protein)