Syncytium formation induced by viral infection ~ ViralZone

Syncytia result from the fusion of an infected cell with neighboring cells, leading to the formation of multinucleated, enlarged cells. This process is triggered by the surface expression of viral fusion proteins that are fusogenic directly at the host cell membrane.

Syncytia can only arise with viruses that are able to fuse directly at the cell surface without requiring endocytosis.

Syncytium formation induced by viral infection

Matching UniProtKB/Swiss-Prot entries

Fusion glycoprotein F0

Envelope glycoprotein K (Syncytial protein)