Polerovirus (taxid:119164)



Non-enveloped, spherical virion about 23 nm in diameter with T=3 icosahedral symmetry composed of 180 CP proteins, with some percentage containing a readthrough domain (RTD) extension located on the particle's surface.



Monopartite, linear, ssRNA(+) genome of 5.3-5.7 kb in size with a VPg bound at the 5' end. There is no poly(A) tail or tRNA-like structure at the 3' end.


The virion RNA is infectious and serves as both the genome and viral messenger RNA. The polymerase is expressed by a ribosomal frameshifting near the end of ORF1. Rap1 translation initiates about 1500 nt downstream of the 5' end of the gRNA by an unusual internal ribosome entry site (IRES).
The movement protein (MVP) and P3a are expressed by leaky scanning of the subgenomic mRNA. Suppression of termination of the CP stop codon produces CP-RTD (CP extended), the capsid subunit essential for aphid transmission.




  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA ORF1 and ORF2 are translated to produce the RdRp fusion protein.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the 3' coterminal sgRNAs. Traduction of these sgRNAs yields the capsid, CP-RTD and movement proteins.
  7. Virus assembly.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Polerovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

29 entries grouped by strain

9 entries

Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain

P1_PLRV1 Protein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1) [Cleaved into: Serine ...
RDRP_PLRV1 Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...
MVP_PLRV1 Movement protein P17 (MP) (17 kDa protein) (MP17)
MCAPS_PLRV1 Readthrough protein P3-RTD (P3-P5 readthrough protein) (P74) (Readthrough protein) (RT protein) ...
P3A_PLRV1 Movement protein P3a (Protein ORF3a)
P0_PLRV1 Suppressor of silencing P0 (28 kDa protein) (Protein ORF0)
CAPSD_PLRV1 Major capsid protein (Coat protein) (CP) (P3)
RAP1_PLRV1 Replication-associated protein (Rap1)
P6_PLRV1 Uncharacterized protein P6 (ORF6 protein)

7 entries

Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

MCAPS_TYYVF Readthrough protein P3-RTD (P3-P5 readthrough protein) (P74) (Readthrough protein) (RT protein) ...
P1_TYYVF Protein P1 (66.2 kDa protein) (Genome-linked protein precursor) (Protein ORF1) [Cleaved into: Serine ...
RDRP_TYYVF Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...
MVP_TYYVF Movement protein (MP) (20 kDa protein)
P3A_TYYVF P3a (Protein ORF3a)
P0_TYYVF Suppressor of silencing P0 (29 kDa protein) (Protein ORF0)
CAPSD_TYYVF Major capsid protein (Coat protein) (CP)

8 entries

Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

P1_PLRVW Protein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1) [Cleaved into: Serine ...
RDRP_PLRVW Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...
MCAPS_PLRVW Readthrough protein P3-RTD (P3-P5 readthrough protein) (P74) (Readthrough protein) (RT protein) ...
MVP_PLRVW Movement protein P17 (MP) (17 kDa protein) (MP17)
P0_PLRVW Suppressor of silencing P0 (28 kDa protein) (Protein ORF0)
CAPSD_PLRVW Major capsid protein (Coat protein) (CP) (P3)
P6_PLRVW Uncharacterized protein P6 (ORF6 protein)
RAP1_PLRVW Replication-associated protein (Rap1)

2 entries

Potato leafroll virus (PLrV)

MVP_PLRV Movement protein P17 (MP) (17 kDa protein) (MP17)
CAPSD_PLRV Major capsid protein (Coat protein) (CP) (P3)

2 entries

Potato leafroll virus (strain Potato/Canada/Rowhani/1979) (PLrV)

MVP_PLRVR Movement protein P17 (MP) (17 kDa protein) (MP17)
CAPSD_PLRVR Major capsid protein (Coat protein) (CP) (P3)

1 entry

Beet western yellows virus (isolate GB1) (BWYV)

MVP_BWYVG Movement protein (MP) (20 kDa protein)
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Barley virus G taxid:1825924

Protein ModelArchive
PO protein ma-jd-viral-55375
Readthrough protein ma-jd-viral-05299
p1 ma-jd-viral-42847
p1-P2 fusion protein ma-jd-viral-19462
p3 ma-jd-viral-28489
p4 ma-jd-viral-01301

Brassica yellows virus taxid:1046403

Protein ModelArchive
Coat protein ma-jd-viral-28496
Movement protein ma-jd-viral-01281
P0 ma-jd-viral-08576
P1 ma-jd-viral-42834
P1-2 fusion protein ma-jd-viral-19439
Read-through protein ma-jd-viral-02274

Chickpea chlorotic stunt virus taxid:328430

Protein ModelArchive
Coat protein ma-jd-viral-28472
Movement protein ma-jd-viral-01286
Readthrough protein ma-jd-viral-05283
p0 protein ma-jd-viral-08571
p1 protein ma-jd-viral-42851

Cotton leafroll dwarf virus taxid:312295

Protein ModelArchive
PO protein ma-jd-viral-08594
RNA-dependent RNA polymerase P1-P2 protein ma-jd-viral-19460
Readthrough protein ma-jd-viral-05288
p1 protein ma-jd-viral-42842
p3 coat protein ma-jd-viral-28476
p4 protein ma-jd-viral-01285

Ixeridium yellow mottle virus 1 taxid:1809767

Protein ModelArchive
P0 protein ma-jd-viral-08574
Peptidase S39 domain-containing protein ma-jd-viral-42839
Putative coat protein P3 ma-jd-viral-28463
Putative fusion protein P1-P2 ma-jd-viral-19454
Putative movement protein P4 ma-jd-viral-01307
Readthrough protein ma-jd-viral-05277

Luffa aphid-borne yellows virus taxid:1462682

Protein ModelArchive
p0 ma-jd-viral-08593
p1 ma-jd-viral-42838
p1-P2 ma-jd-viral-19433
p3 ma-jd-viral-28497
p3-P5 ma-jd-viral-05292
p4 ma-jd-viral-01275

Maize yellow dwarf virus-RMV2 taxid:1833824

Protein ModelArchive
RNA-directed RNA polymerase (EC ma-jd-viral-19800
p0 ma-jd-viral-55376
p1 ma-jd-viral-42853
p3 ma-jd-viral-28498
p4 ma-jd-viral-01288
p5 ma-jd-viral-02273

Melon aphid-borne yellows virus taxid:471717

Protein ModelArchive
Coat protein (p3) ma-jd-viral-28481
Movement protein ma-jd-viral-01299
Readthrough protein ma-jd-viral-05284
p0 ma-jd-viral-08579
p1 ma-jd-viral-42844
p1-P2 fusion protein ma-jd-viral-19463

Pepo aphid-borne yellows virus taxid:1462681

Protein ModelArchive
Readthrough protein ma-jd-viral-05289
p0 ma-jd-viral-08590
p1 ma-jd-viral-42845
p1-P2 fusion protein ma-jd-viral-19441
p3 ma-jd-viral-28491
p4 ma-jd-viral-01300

Pepper vein yellows virus taxid:909827

Protein ModelArchive
Putative P0 protein ma-jd-viral-08581
Putative P1 protein ma-jd-viral-42827
Putative P1-P2 fusion protein ma-jd-viral-19449
Putative P3 protein ma-jd-viral-28495
Putative P4 protein ma-jd-viral-01292
Readthrough protein ma-jd-viral-05275

Phasey bean mild yellows virus taxid:1756832

Protein ModelArchive
Coat protein ma-jd-viral-28484
Movement protein ma-jd-viral-01298
P0 protein ma-jd-viral-08575
P1 protein ma-jd-viral-42852
RNA-dependent RNA polymerase ma-jd-viral-19448

Sauropus yellowing virus taxid:1577997

Protein ModelArchive
p0 ma-jd-viral-08585
p1 ma-jd-viral-42837
p1-P2 fusion protein ma-jd-viral-19452
p3 ma-jd-viral-28469
p3-P5 readthrough protein ma-jd-viral-05293
p4 ma-jd-viral-01280

Strawberry polerovirus 1 taxid:1564903

Protein ModelArchive
Coat protein (p3) ma-jd-viral-28494
Readthrough protein ma-jd-viral-05300
p0 ma-jd-viral-08589
p1 ma-jd-viral-42848
p1-P2 fusion protein ma-jd-viral-19445
p4 ma-jd-viral-34494

Suakwa aphid-borne yellows virus taxid:646010

Protein ModelArchive
Readthrough protein ma-jd-viral-05286
p0 ma-jd-viral-08591
p1 ma-jd-viral-42833
p1-P2 fusion protein ma-jd-viral-19442
p3 ma-jd-viral-28485
p4 ma-jd-viral-01282

Sugarcane yellow leaf virus taxid:94290

Protein ModelArchive
Capsid protein (Coat protein) ma-jd-viral-28474
Movement protein (Putative 17 kDa movement protein) (Putative movement protein) ma-jd-viral-01293
ORF 0 ma-jd-viral-60833
Putative aphid transmission factor ma-jd-viral-05304
RNA-directed RNA polymerase (EC ma-jd-viral-18936

Tobacco vein distorting virus taxid:192203

Protein ModelArchive
CP protein ma-jd-viral-28501
Putative MP protein ma-jd-viral-01294
Putative P0 protein ma-jd-viral-08582
Readthrough protein ma-jd-viral-05280
Uncharacterized protein P1 ma-jd-viral-42830

Wheat yellow dwarf virus-GPV taxid:572239

Protein ModelArchive
Coat protein ma-jd-viral-28486
P0 protein ma-jd-viral-08587
Peptidase S39 domain-containing protein ma-jd-viral-42826
Readthrough protein ma-jd-viral-05287
Uncharacterized protein ma-jd-viral-01295

White clover mottle virus taxid:1913024

Protein ModelArchive
Coat protein ma-jd-viral-28466
Movement protein ma-jd-viral-01303
RNA-dependent RNA polymerase ma-jd-viral-19444
RNA-dependent RNA polymerase P1 protein ma-jd-viral-42849
Readthrough protein ma-jd-viral-05285
p0 protein ma-jd-viral-08572