Reptarenavirus (taxid:1653395)



Enveloped, spherical. Diameter from 60 to 300 nm.



Segmented Negative-stranded RNA linear genome, L segment is about 6.9 kb and S segment 3.4 kb.
Encodes four proteins.


Both segments are ambisens. The viral RNA dependent RNA polymerase (L) binds to a promoter on each encapsidated segment, and transcribes a messenger RNA. Transcription is terminated by a strong hairpin sequence at the end of each gene. mRNAs are capped, probably by L protein during synthesis.




  1. Virus attaches to host receptors though GP glycoprotein and is endocytosed into vesicles in the host cell by apoptotic mimicry.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released in the cytoplasm.
  3. Sequential transcription, viral mRNAs are capped in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid interacts with the Z protein under the plasma membrane and buds, releasing the virion.

Matching UniProtKB/Swiss-Prot entries

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4 entries grouped by strain

4 entries

Alethinophid 1 reptarenavirus (isolate AlRrV1/Boa/USA/BC/2009) (Golden Gate virus) reference strain

L_GOGV RNA-directed RNA polymerase L (Protein L) (EC (Large structural protein) (Replicase) ...
NCAP_GOGV Nucleoprotein (Nucleocapsid protein) (Protein N)
GLYC_GOGV Glycoprotein
MEM_GOGV Putative membrane protein
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Alethinophid 1 reptarenavirus (isolate AlRrV1/Boa/USA/BC/2009) taxid:1223562

Protein ModelArchive
Glycoprotein ma-jd-viral-51469
Nucleoprotein (Nucleocapsid protein) (Protein N) ma-jd-viral-04945
Putative membrane protein ma-jd-viral-62943

CAS virus taxid:1223561

Protein ModelArchive
Glycoprotein ma-jd-viral-51468
Nucleoprotein ma-jd-viral-04963
Z protein ma-jd-viral-62945

ROUT virus taxid:1303019

Protein ModelArchive
Glycoprotein ma-jd-viral-51470
Nucleocapsid protein ma-jd-viral-04956
Z protein ma-jd-viral-62947

University of Helsinki virus taxid:1382279

Protein ModelArchive
Glycoprotein ma-jd-viral-51471
Nucleoprotein ma-jd-viral-04942
Z protein ma-jd-viral-62944