Autographiviridae

VIRION

Non-enveloped, head-tail structure. Head is about 60 nm in diameter. The tail is non-contractile, has 6 short subterminal fibers. The capsid is icosahedral with a T=7 symmetry.

GENOME

Linear, dsDNA genome of about 40-42 kb encoding for 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription of class I genes by host RNA polymerase before the viral genome completely exits out of capsid.
  4. Transcription of class II genes by T7 RNA polymerase.
  5. Bacterial genome degradation
  6. Replication of genomic DNA by T7 DNA polymerase, formation of viral genome concatemers.
  7. Transcription of class III genes by T7 RNA polymerase.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

113 entries grouped by strain (browse by keywords)

57 entries

Escherichia phage T7 (Bacteriophage T7) reference strain

Select_allDeselect_all
TERL_BPT7 Terminase, large subunit (DNA-packaging protein) (Gene product 19) (Gp19) [Includes: ATPase (EC ...
SGS_BPT7 Protein suppressor of silencing (Gene product 5.5)
SPAN1_BPT7 Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)
PK_BPT7 Protein kinase 0.7 (EC 2.7.11.1) (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)
RPOL_BPT7 T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)
VRPI_BPT7 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)
TERS_BPT7 Terminase, small subunit gp18 (DNA-packaging protein A) (Gene product 18) (Gp18)
SCAF_BPT7 Capsid assembly scaffolding protein (Gene product 9) (Gp9) (Head morphogenesis protein) (Scaffold ...
SPAN2_BPT7 Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)
PORTL_BPT7 Portal protein (Gene product 8) (Gp8) (Head-to-tail connector)
Y7_BPT7 Protein 7 (Gene product 7) (Gp7)
Y53_BPT7 Protein 5.3 (Gene product 5.3) (Gp5.3)
Y05_BPT7 Protein 0.5 (Gene product 0.5) (Gp0.5)
Y11_BPT7 Uncharacterized protein 1.1 (Gene product 1.1) (Gp1.1)
Y43_BPT7 Protein 4.3 (Gene product 4.3) (Gp4.3)
Y15_BPT7 Protein 1.5 (Gene product 1.5) (Gp1.5)
Y195_BPT7 Protein 19.5 (Gene product 19.5) (Gp19.5)
OCR_BPT7 Protein Ocr (Gene product 0.3) (Gp0.3) (Overcome classical restriction) (Ocr)
NUCK_BPT7 Nucleotide kinase gp1.7 (Gene product 1.7) (Gp1.7)
Y192_BPT7 Protein 19.2 (Gene product 19.2) (Gp19.2)
V5557_BPT7 Fusion protein 5.5/5.7
Y06_BPT7 Protein 0.6B [Cleaved into: Protein 0.6A]
Y28_BPT7 Protein 2.8 (Gene product 2.8) (Gp2.8)
Y193_BPT7 Protein 19.3 (Gene product 19.3) (Gp19.2)
Y63_BPT7 Protein 6.3 (Gene product 6.3) (Gp6.3)
Y47_BPT7 Protein 4.7 (Gene product 4.7) (Gp4.7)
GP13_BPT7 Probable scaffold protein gp13 (Gene product 13) (Gp13)
PRIM_BPT7 DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)
GP12_BPT7 Inhibitor of dGTPase (Gene product 1.2) (Gp1.2) (Inhibitor of dGTPase gp1.2)
GP04_BPT7 Gene 0.4 protein (Gene product 0.4) (Gp0.4)
ENLYS_BPT7 Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (T7 endolysin)
ITAS_BPT7 Inhibitor of toxin/antitoxin system (Gene product 4.5) (Gp4.5)
DNBI_BPT7 Single-stranded DNA-binding protein gp2.5 (SSB protein)
GP59_BPT7 Probable RecBCD inhibitor gp5.9 (Gene product 5.9) (Gp5.9)
GP67_BPT7 Protein 6.7 (Gene product 6.7) (Gp6.7)
GP73_BPT7 Protein 7.3 (Gene product 7.3) (Gp7.3)
GP14_BPT7 Internal virion protein gp14 (Gene product 14) (Gp14)
ENDO_BPT7 Endonuclease I (EC 3.1.21.2) (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)
EXRN_BPT7 Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3)
GP15_BPT7 Internal virion protein gp15 (Gene product 15) (Gp15)
EXLYS_BPT7 Peptidoglycan transglycosylase gp16 (EC 4.2.2.n1) (Internal core protein gp16)
DNLI_BPT7 DNA ligase (EC 6.5.1.1) (DNA ligase gp1.3) (Gene product 1.3) (Gp1.3)
CAPSB_BPT7 Minor capsid protein (Gene product 10B) (Gp10B) (Minor head protein)
HOLIN_BPT7 Holin (Gene product 17.5) (Gp17.5)
FIBER_BPT7 Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)
DPOL_BPT7 DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)
CAPSA_BPT7 Major capsid protein (Gene product 10A) (Gp10A) (Major head protein)
Y65_BPT7 Protein 6.5 (Gene product 6.5) (Gp6.5)
Y38_BPT7 Protein 3.8 (Gene product 3.8) (Gp3.8)
Y41_BPT7 Protein 4.1 (Gene product 4.1) (Gp4.1)
Y42_BPT7 Preotein 4.2 (Gene product 4.2) (Gp4.2)
Y18_BPT7 Protein 1.8 (Gene product 1.8) (Gp1.8)
Y14_BPT7 Protein 1.4 (Gene product 1.4) (Gp1.4)
Y16_BPT7 Protein 1.6 (Gene product 1.6) (Gp1.6)
TUBE1_BPT7 Tail tubular protein gp11 (Gene product 11) (Gp11)
Y77_BPT7 Protein 7.7 (Gene product 7.7) (Gp7.7)
TUBE2_BPT7 Tail tubular protein gp12 (Gene product 12) (Gp12)

1 entry

Enterobacteria phage T3 (Bacteriophage T3) reference strain

ADOM_BPT3 S-adenosyl-L-methionine hydrolase (ADOMetase) (Adenosylmethionine hydrolase) (SAMase) (EC 3.3.1.2)

8 entries

Pseudomonas phage phiKMV reference strain

Select_allDeselect_all
PORTL_BPKMV Portal protein (Head-to-tail connector)
SPAN1_BPKMV Probable spanin, inner membrane subunit (i-spanin)
SPAN2_BPKMV Probable spanin, outer lipoprotein subunit
RPOL_BPKMV DNA-directed RNA polymerase (EC 2.7.7.6)
HOLIN_BPKMV Holin (KMV44) (Pinholin)
EXLYS_BPKMV Peptidoglycan hydrolase gp36 (EC 3.2.1.17) (Gene product 36) (Gp36)
ENLYS_BPKMV SAR-endolysin (EC 3.2.1.17) (Endolysin) (Gene product 45) (gp45) (KMV45) (Lysis protein) (Lysozyme) ...
CAPSD_BPKMV Major capsid protein (Gene product 32) (gp32) (Major head protein)

2 entries

Enterobacteria phage SP6 (Bacteriophage SP6) reference strain

Select_allDeselect_all
EXLYS_BPSP6 Peptidoglycan hydrolase gp36 (Gene product 36) (Gp36)
PORTL_BPSP6 Portal protein (Head-to-tail connector)

1 entry

Escherichia phage K1F (Bacteriophage K1F) reference strain

FIBER_BPK1F Tail spike protein (TSP) (Endo-N-acetylneuraminidase) (Endo-N) (EC 3.2.1.129) (Endo-alpha-sialidase) ...

42 entries

Enterobacteria phage T3 (Bacteriophage T3)

Select_allDeselect_all
V17_BPT3 Gene 1.7 protein
V59_BPT3 Gene 5.9 protein
V193_BPT3 Gene 19.3 protein
V55_BPT3 Gene 5.5 protein
SPAN1_BPT3 Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)
SPAN2_BPT3 Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)
Y65_BPT3 Uncharacterized gene 6.5 protein
V45_BPT3 Gene 4.5 protein
RPOL_BPT3 DNA-directed RNA polymerase (EC 2.7.7.6)
Y53_BPT3 Uncharacterized gene 5.3 protein
V42_BPT3 Gene 4.2 protein
Y63_BPT3 Uncharacterized gene 6.3 protein
TERL_BPT3 Terminase, large subunit (DNA-packaging protein) (Gene product 19) (gp19) [Includes: ATPase (EC ...
SCAF_BPT3 Capsid assembly scaffolding protein (Capsid assembly protein) (Gene product 9) (Gp9) (Head ...
VRPI_BPT3 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)
VDMA_BPT3 DNA maturase A (DNA-packaging protein A) (GP18)
Y67_BPT3 Uncharacterized gene 6.7 protein
Y105_BPT3 Uncharacterized gene 1.05 protein
PRIM_BPT3 DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12)
ENRN_BPT3 Endodeoxyribonuclease 1 (EC 3.1.21.2) (Endodeoxyribonuclease I) (Endonuclease)
GP73_BPT3 Protein 7.3 (Gene product 7.3) (Gp7.3) (Host specificity protein B)
CAPSA_BPT3 Major capsid protein (Gene product 10A) (Gp10A) (Major head protein)
EXRN_BPT3 Exodeoxyribonuclease (Exonuclease) (EC 3.1.11.3)
DPOL_BPT3 DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)
ENLYS_BPT3 Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (T3 lysozyme)
CAPSB_BPT3 Minor capsid protein (Gene product 10B) (Gp10B) (Minor head protein)
FIBER_BPT3 Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)
DNLI_BPT3 DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
HOLIN_BPT3 Holin (Lysis protein)
PORTL_BPT3 Portal protein (Gene product 8) (Gp8) (Head-to-tail connector)
Y18_BPT3 Uncharacterized gene 1.8 protein
V192_BPT3 Gene 19.2 protein
V43_BPT3 Gene 4.3 protein
Y16_BPT3 Uncharacterized gene 1.6 protein
V57_BPT3 Gene 5.7 protein
Y15_BPT3 Uncharacterized gene 1.5 protein
Y195_BPT3 Uncharacterized gene 19.5 protein
Y51_BPT3 Uncharacterized gene 5.1 protein
VHED_BPT3 Helix-destabilizing protein (Single-stranded DNA-binding protein) (SSB protein)
V11_BPT3 Gene 1.1 protein
V12_BPT3 Gene 1.2 protein
Y37_BPT3 Uncharacterized gene 3.7 protein

1 entry

Enterobacteria phage SP6 (Bacteriophage SP6)

RPOL_BPSP6 DNA-directed RNA polymerase (EC 2.7.7.6)

1 entry

Escherichia phage K1E (Bacteriophage K1E)

FIBER_BPK1E Tail spike protein (TSP) (Endo-N-acetylneuraminidase) (Endo-N) (EC 3.2.1.129) (Endo-alpha-sialidase) ...