Lolavirus (taxid:675076)



Non-enveloped, flexuous, filamentous, about 640 nm long and 13 nm in diameter.


Linear ssRNA(+) genome of 7.6 kb in size. The 3' terminus is polyadenylated. Encodes 6 proteins.


The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS, are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs).




  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Matching UniProtKB/Swiss-Prot entries

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6 entries grouped by strain

6 entries

Lolium latent virus (isolate Lolium/USA/US1/-) (LoLV) reference strain

RDRP_LOLV RNA-directed RNA polymerase (EC [Includes: Helicase (EC]
CAPSD_LOLV Capsid protein (CP) (Coat protein)
TGB1_LOLV Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block ...
TGB2_LOLV Movement protein TGB2 (14 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_LOLV Movement protein TGBp3 (Triple gene block 3 protein) (TGBp3)
ORF6_LOLV Uncharacterized ORF6 protein