Mycoflexivirus (taxid:675062)



Non-enveloped, flexuous, filamentous, about 720 nm long and 12-13 nm in diameter.



Linear ssRNA(+) genome of 6.8 kb in size. The 5' end may possibly be capped and 3' terminus is polyadenylated. Encodes for 2 ORFs.


The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA by readthrough of a 'leaky' stop codon between the helicase and RdRp regions. The capsid (coat) protein is transcribed presumably as a monocistronic subgenomic mRNA (sgRNA).




  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoter is used to transcribe the sgRNA. Traduction of this sgRNA yields the capsid protein.
  7. Assembly of new virus particles.

Matching UniProtKB/Swiss-Prot entries

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2 entries grouped by protein

1 entry

Capsid protein (CP) (Coat protein)

Botrytis virus F (isolate Botrytis cinerea/New Zealand/Howitt/2001) (BotV-F) reference strain

1 entry

RNA replication protein

Botrytis virus F (isolate Botrytis cinerea/New Zealand/Howitt/2001) (BotV-F) reference strain
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Botrytis virus F (isolate Botrytis cinerea/New Zealand/Howitt/2001) taxid:686946

Protein ModelArchive
Capsid protein (CP) (Coat protein) ma-jd-viral-61696