Gemyvongvirus (taxid:1985370)



Non-enveloped, round, T=1 icosahedral symmetry, about 20 nm in diameter.



Monopartite, circular, ssDNA genome genome of about 2.27 kb. There are coding regions in both the virion (positive) and complementary (negative) sense strands.
The replication (Rep) protein initiates and terminates rolling circle replication. Two intergenic regions separate the two ORFs.
The short intergenic region contains bidirectional polyadenylation signals.


Transcription is bidirectional from the long intergenic region (LIR) which contains two divergent promoters. The resulting transcripts encode a capsid protein and a replication-associated protein.



  1. Virus attaches to host cell, and genomic DNA penetrates into the cytoplasm.
  2. Presumably the ssDNA is converted to dsDNA.
  3. Transcription of viral genes, possibly by a host RNA polymerase.
  4. Genome replication, possibly by rolling circle
  5. Assembly and release of virions.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Human plasma-associated gemycircularvirus taxid:1707330

Protein ModelArchive
Capsid protein ma-jd-viral-28702
Putative ORF3 protein ma-jd-viral-43129
Replication-associated protein ma-jd-viral-20382