Gammatorquevirus (taxid:687333)



Non-enveloped, T=1 icosahedral symmetry, with a diameter of about 30-32nm.


Circular ssDNA genome (-) genome of about 3.8 kb.
The genome is replicated through double-stranded intermediates. It may encode for 4 proteins: ORF1 (Rep protein?), ORF2, ORF3 and ORF4.


The proteins are expressed by alternative splicing of pre-mRNA.



  1. Virus penetrates into the host cell.
  2. Uncoating, the viral ssDNA genome penetrates into the nucleus.
  3. The ssDNA is converted into dsDNA with the participation of cellular factors. dsDNA transcription gives rise to viral mRNAs.
  4. viral mRNAs are transcribed and translated to produce viral proteins.
  5. Replication may be mediated by a "Rep-like" protein, and would occur by rolling circle producing ssDNA genomes.
  6. These newly synthesized ssDNA can either
    a) be converted to dsDNA and serve as a template for transcription/replication
    b) be encapsidated by capsid protein and form virions released by cell lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to website)

2 entries grouped by protein

1 entry

Capsid protein

Torque teno midi virus 1 (isolate MD1-073) reference strain

1 entry

Uncharacterized ORF3 protein

Torque teno midi virus 1 (isolate MD1-073) reference strain
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Torque teno midi virus 1 taxid:687379

Protein ModelArchive
Capsid protein ma-jd-viral-04588
Capsid protein ma-jd-viral-31804
Capsid protein ma-jd-viral-31805
Capsid protein ma-jd-viral-37338

Torque teno midi virus 2 taxid:687380

Protein ModelArchive
Capsid protein ma-jd-viral-04589
Capsid protein ma-jd-viral-37345
Capsid protein ma-jd-viral-40489
Capsid protein ma-jd-viral-40496