No data available (08/2017)
Segmented, quadripartite, linear, ssRNA(+) genome. The four segments are about 5.9, 3.9, 2.6 and 1.7 kb in size. The genomic RNA is capped, but not polyadenylated.
Genomic RNAs serve as messenger RNAs. RNA1 contains 1 ORF encoding the methyltransferase, protease, and helicase domains. RNA2 encodes a second helicase domain and an RNA-dependent RNA polymerase (RdRp) domain. RNA3 encodes five ORFs (p7, p9, p22, p28 and p31), and RNA4 seems to encode a movement protein.
- Virus penetrates into the host cell.
- Uncoating, and release of the viral genomic RNA into the cytoplasm.
- The viral RNA is translated to produce the proteins necessary for RNA synthesis (replication and transcription).
- Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
- The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
- Each segment is encapsidated.
- Viral movement protein probably mediates virion cell-to-cell transfer.