Platypuvirus (taxid:1921433)

VIRION

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Non-enveloped, flexuous, filamentous, 800 nm long and 12 nm in diameter.

GENOME

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Linear ssRNA(+) genome of 9 kb in size. The 3' terminus is polyadenylated, and 5' terminus presumably capped. Encodes for 6 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are presumably transcribed as monocistronic subgenomic mRNAs (sgRNAs).

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Donkey orchid symptomless virus taxid:1400526

Protein ModelArchive
27 kDa protein ma-jd-viral-61832
44 kDa protein ma-jd-viral-60338
69 kDa protein ma-jd-viral-36416
Coat protein ma-jd-viral-16045
Movement protein ma-jd-viral-27949
Replicase ma-jd-viral-34101