T7virus

VIRION

Non-enveloped, head-tail structure. Head is about 60 nm in diameter. The tail is non-contractile, has 6 short subterminal fibers. The capsid is icosahedral with a T=7 symmetry.

GENOME

Linear, dsDNA genome of about 40-42 kb encoding for about 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription of class I genes by host RNA polymerase before the viral genome completely exits out of capsid.
  4. Transcription of class II genes by T7 RNA polymerase.
  5. Bacterial genome degradation
  6. Replication of genomic DNA by T7 DNA polymerase, formation of viral genome concatemers.
  7. Transcription of class III genes by T7 RNA polymerase.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

101 entries grouped by protein (browse by keywords)

All proteins are shown (view only 59 complete proteome entries)

1 entry

S-adenosyl-L-methionine hydrolase (ADOMetase) (Adenosylmethionine hydrolase) (SAMase) (EC 3.3.1.2)

ADOM_BPT3
Enterobacteria phage T3 (Bacteriophage T3) reference strain

2 entries

Major capsid protein 10A (Gene product 10A) (Gp10A) (Major head protein 10A)

Select_allDeselect_all
CAPSA_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
CAPSA_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

Minor capsid protein 10B (Gene product 10B) (Gp10B) (Minor head protein 10B)

Select_allDeselect_all
CAPSB_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
CAPSB_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Minor capsid protein 10B (Minor head protein 10B)

1 entry

Single-stranded DNA-binding protein gp2.5 (SSB protein)

DNBI_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

DNA ligase (EC 6.5.1.1) (DNA ligase gp1.3) (Gene product 1.3) (Gp1.3)

Select_allDeselect_all
DNLI_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
DNLI_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase

2 entries

DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)

Select_allDeselect_all
DPOL_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
DPOL_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Endonuclease I (EC 3.1.21.2) (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)

ENDO_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Select_allDeselect_all
ENLYS_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
ENLYS_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (T3 lysozyme)

1 entry

Endodeoxyribonuclease 1 (EC 3.1.21.2) (Endodeoxyribonuclease I) (Endonuclease)

ENRN_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Peptidoglycan hydrolase gp16 (EC 4.2.2.n1) (Gene product 16) (Gp16) (Internal virion protein gp16)

EXLYS_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Exodeoxyribonuclease (Exonuclease) (EC 3.1.11.3)

Select_allDeselect_all
EXRN_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3)

EXRN_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

3 entries

Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)

Select_allDeselect_all
FIBER_BPK1F
Enterobacteria phage K1F (Bacteriophage K1F) reference strain

Tail spike protein (TSP) (Endo-N-acetylneuraminidase) (Endo-N) (EC 3.2.1.129) (Endo-alpha-sialidase) (EndoNF) (G102)

FIBER_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
FIBER_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 0.4 protein (Gene product 0.4) (Gp0.4)

GP04_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Inhibitor of dGTPase (Gene product 1.2) (Gp1.2) (Inhibitor of dGTPase gp1.2)

GP12_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Probable scaffold protein gp13 (Gene product 13) (Gp13)

GP13_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Internal virion protein gp14 (Gene product 14) (Gp14)

GP14_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Internal virion protein gp15 (Gene product 15) (Gp15)

GP15_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Probable RecBCD inhibitor gp5.9 (Gene product 5.9) (Gp5.9)

GP59_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 6.7 (Gene product 6.7) (Gp6.7)

GP67_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Protein 7.3 (Gene product 7.3) (Gp7.3)

Select_allDeselect_all
GP73_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
GP73_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Protein 7.3 (Gene product 7.3) (Gp7.3) (Host specificity protein B)

2 entries

Holin (Gene product 17.5) (Gp17.5)

Select_allDeselect_all
HOLIN_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
HOLIN_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Holin (Lysis protein)

1 entry

Inhibitor of toxin/antitoxin system (Gene product 4.5) (Gp4.5)

ITAS_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Nucleotide kinase gp1.7 (Gene product 1.7) (Gp1.7)

NUCK_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Overcome classical restriction gp0.3 (Gene product 0.3) (Gp0.3) (OCR)

OCR_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein kinase 0.7 (EC 2.7.11.1) (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)

PK_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Portal protein (Gene product 8) (Gp8) (Head-to-tail connector gp8)

Select_allDeselect_all
PORTL_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
PORTL_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Portal protein (Gene product 8) (Gp8) (Head-to-tail connector gp8) (Head-to-tail joining protein)

2 entries

DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12)

Select_allDeselect_all
PRIM_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)

PRIM_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

DNA-directed RNA polymerase (EC 2.7.7.6)

Select_allDeselect_all
RPOL_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)

RPOL_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

Capsid assembly scaffolding protein (Capsid assembly protein) (Gene product 9) (Gp9) (Head morphogenesis protein) (Scaffold protein) (Scaffolding protein)

Select_allDeselect_all
SCAF_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

Capsid assembly scaffolding protein (Gene product 9) (Gp9) (Head morphogenesis protein) (Scaffold protein)

SCAF_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Protein suppressor of silencing (Gene product 5.5)

SGS_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)

Select_allDeselect_all
SPAN1_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
SPAN1_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)

Select_allDeselect_all
SPAN2_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
SPAN2_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

Terminase, large subunit gp19 (EC 3.1.-.-) (DNA maturase B) (DNA-packaging protein B) (Gene product 19) (gp19)

Select_allDeselect_all
TERL_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

Terminase, large subunit gp19 (EC 3.1.-.-) (DNA-packaging protein B) (Gene product 19) (Gp19)

TERL_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Terminase, small subunit gp18 (DNA-packaging protein A) (Gene product 18) (Gp18)

TERS_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Tail tubular protein gp11 (Gene product 11) (Gp11)

TUBE1_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Tail tubular protein gp12 (Gene product 12) (Gp12)

TUBE2_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Gene 1.1 protein

V11_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 1.2 protein

V12_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 1.7 protein

V17_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 19.2 protein

V192_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 19.3 protein

V193_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 4.2 protein

V42_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 4.3 protein

V43_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 4.5 protein

V45_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 5.5 protein

V55_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Fusion protein 5.5/5.7

V5557_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Gene 5.7 protein

V57_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Gene 5.9 protein

V59_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

DNA maturase A (DNA-packaging protein A) (GP18)

VDMA_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Helix-destabilizing protein (Single-stranded DNA-binding protein) (SSB protein)

VHED_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)

Select_allDeselect_all
VRPI_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
VRPI_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Protein 0.5 (Gene product 0.5) (Gp0.5)

Y05_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 0.6B

Y06_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Uncharacterized gene 1.05 protein

Y105_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Uncharacterized protein 1.1 (Gene product 1.1) (Gp1.1)

Y11_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 1.4 (Gene product 1.4) (Gp1.4)

Y14_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Protein 1.5 (Gene product 1.5) (Gp1.5)

Select_allDeselect_all
Y15_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y15_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 1.5 protein

2 entries

Protein 1.6 (Gene product 1.6) (Gp1.6)

Select_allDeselect_all
Y16_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y16_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 1.6 protein

2 entries

Protein 1.8 (Gene product 1.8) (Gp1.8)

Select_allDeselect_all
Y18_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y18_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 1.8 protein

1 entry

Protein 19.2 (Gene product 19.2) (Gp19.2)

Y192_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 19.3 (Gene product 19.3) (Gp19.2)

Y193_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

2 entries

Protein 19.5 (Gene product 19.5) (Gp19.5)

Select_allDeselect_all
Y195_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y195_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 19.5 protein

1 entry

Protein 2.8 (Gene product 2.8) (Gp2.8)

Y28_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Uncharacterized gene 3.7 protein

Y37_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Protein 3.8 (Gene product 3.8) (Gp3.8)

Y38_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 4.1 (Gene product 4.1) (Gp4.1)

Y41_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Preotein 4.2 (Gene product 4.2) (Gp4.2)

Y42_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 4.3 (Gene product 4.3) (Gp4.3)

Y43_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 4.7 (Gene product 4.7) (Gp4.7)

Y47_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Uncharacterized gene 5.1 protein

Y51_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

2 entries

Protein 5.3 (Gene product 5.3) (Gp5.3)

Select_allDeselect_all
Y53_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y53_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 5.3 protein

2 entries

Protein 6.3 (Gene product 6.3) (Gp6.3)

Select_allDeselect_all
Y63_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y63_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 6.3 protein

2 entries

Protein 6.5 (Gene product 6.5) (Gp6.5)

Select_allDeselect_all
Y65_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain
Y65_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Uncharacterized gene 6.5 protein

1 entry

Uncharacterized gene 6.7 protein

Y67_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

1 entry

Protein 7 (Gene product 7) (Gp7)

Y7_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain

1 entry

Protein 7.7 (Gene product 7.7) (Gp7.7)

Y77_BPT7
Enterobacteria phage T7 (Bacteriophage T7) reference strain