T7virus

VIRION

Non-enveloped, head-tail structure. Head is about 60 nm in diameter. The tail is non-contractile, has 6 short subterminal fibers. The capsid is icosahedral with a T=7 symmetry.

GENOME

Linear, dsDNA genome of about 40-42 kb encoding for about 55 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription of class I genes by host RNA polymerase before the viral genome completely exits out of capsid.
  4. Transcription of class II genes by T7 RNA polymerase.
  5. Bacterial genome degradation
  6. Replication of genomic DNA by T7 DNA polymerase, formation of viral genome concatemers.
  7. Transcription of class III genes by T7 RNA polymerase.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

101 entries grouped by strain (browse by keywords)

All proteins are shown (view only 59 complete proteome entries)

57 entries

Enterobacteria phage T7 (Bacteriophage T7) reference strain

Select_allDeselect_all
CAPSA_BPT7 Major capsid protein 10A (Gene product 10A) (Gp10A) (Major head protein 10A)
CAPSB_BPT7 Minor capsid protein 10B (Gene product 10B) (Gp10B) (Minor head protein 10B)
DNLI_BPT7 DNA ligase (EC 6.5.1.1) (DNA ligase gp1.3) (Gene product 1.3) (Gp1.3)
DNBI_BPT7 Single-stranded DNA-binding protein gp2.5 (SSB protein)
DPOL_BPT7 DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)
ENDO_BPT7 Endonuclease I (EC 3.1.21.2) (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)
ENLYS_BPT7 Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)
GP12_BPT7 Inhibitor of dGTPase (Gene product 1.2) (Gp1.2) (Inhibitor of dGTPase gp1.2)
GP13_BPT7 Probable scaffold protein gp13 (Gene product 13) (Gp13)
GP14_BPT7 Internal virion protein gp14 (Gene product 14) (Gp14)
GP73_BPT7 Protein 7.3 (Gene product 7.3) (Gp7.3)
GP04_BPT7 Gene 0.4 protein (Gene product 0.4) (Gp0.4)
GP59_BPT7 Probable RecBCD inhibitor gp5.9 (Gene product 5.9) (Gp5.9)
EXRN_BPT7 Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3)
EXLYS_BPT7 Peptidoglycan hydrolase gp16 (EC 4.2.2.n1) (Gene product 16) (Gp16) (Internal virion protein gp16)
FIBER_BPT7 Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)
GP67_BPT7 Protein 6.7 (Gene product 6.7) (Gp6.7)
GP15_BPT7 Internal virion protein gp15 (Gene product 15) (Gp15)
HOLIN_BPT7 Holin (Gene product 17.5) (Gp17.5)
ITAS_BPT7 Inhibitor of toxin/antitoxin system (Gene product 4.5) (Gp4.5)
PRIM_BPT7 DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12) (Gene product 4) (Gp4)
RPOL_BPT7 T7 RNA polymerase (DNA-directed RNA polymerase) (EC 2.7.7.6)
SCAF_BPT7 Capsid assembly scaffolding protein (Gene product 9) (Gp9) (Head morphogenesis protein) (Scaffold ...
SGS_BPT7 Protein suppressor of silencing (Gene product 5.5)
SPAN1_BPT7 Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)
TUBE2_BPT7 Tail tubular protein gp12 (Gene product 12) (Gp12)
TUBE1_BPT7 Tail tubular protein gp11 (Gene product 11) (Gp11)
VRPI_BPT7 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)
Y14_BPT7 Protein 1.4 (Gene product 1.4) (Gp1.4)
Y06_BPT7 Protein 0.6B [Cleaved into: Protein 0.6A]
Y11_BPT7 Uncharacterized protein 1.1 (Gene product 1.1) (Gp1.1)
Y195_BPT7 Protein 19.5 (Gene product 19.5) (Gp19.5)
Y05_BPT7 Protein 0.5 (Gene product 0.5) (Gp0.5)
Y193_BPT7 Protein 19.3 (Gene product 19.3) (Gp19.2)
Y15_BPT7 Protein 1.5 (Gene product 1.5) (Gp1.5)
Y28_BPT7 Protein 2.8 (Gene product 2.8) (Gp2.8)
Y18_BPT7 Protein 1.8 (Gene product 1.8) (Gp1.8)
Y42_BPT7 Preotein 4.2 (Gene product 4.2) (Gp4.2)
Y43_BPT7 Protein 4.3 (Gene product 4.3) (Gp4.3)
Y77_BPT7 Protein 7.7 (Gene product 7.7) (Gp7.7)
Y47_BPT7 Protein 4.7 (Gene product 4.7) (Gp4.7)
Y16_BPT7 Protein 1.6 (Gene product 1.6) (Gp1.6)
Y192_BPT7 Protein 19.2 (Gene product 19.2) (Gp19.2)
Y7_BPT7 Protein 7 (Gene product 7) (Gp7)
Y38_BPT7 Protein 3.8 (Gene product 3.8) (Gp3.8)
Y53_BPT7 Protein 5.3 (Gene product 5.3) (Gp5.3)
Y41_BPT7 Protein 4.1 (Gene product 4.1) (Gp4.1)
Y63_BPT7 Protein 6.3 (Gene product 6.3) (Gp6.3)
NUCK_BPT7 Nucleotide kinase gp1.7 (Gene product 1.7) (Gp1.7)
OCR_BPT7 Overcome classical restriction gp0.3 (Gene product 0.3) (Gp0.3) (OCR)
PK_BPT7 Protein kinase 0.7 (EC 2.7.11.1) (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)
PORTL_BPT7 Portal protein (Gene product 8) (Gp8) (Head-to-tail connector gp8)
SPAN2_BPT7 Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)
TERL_BPT7 Terminase, large subunit gp19 (EC 3.1.-.-) (DNA-packaging protein B) (Gene product 19) (Gp19)
TERS_BPT7 Terminase, small subunit gp18 (DNA-packaging protein A) (Gene product 18) (Gp18)
V5557_BPT7 Fusion protein 5.5/5.7
Y65_BPT7 Protein 6.5 (Gene product 6.5) (Gp6.5)

1 entry

Enterobacteria phage T3 (Bacteriophage T3) reference strain

ADOM_BPT3 S-adenosyl-L-methionine hydrolase (ADOMetase) (Adenosylmethionine hydrolase) (SAMase) (EC 3.3.1.2)

1 entry

Enterobacteria phage K1F (Bacteriophage K1F) reference strain

FIBER_BPK1F Tail spike protein (TSP) (Endo-N-acetylneuraminidase) (Endo-N) (EC 3.2.1.129) (Endo-alpha-sialidase) ...

42 entries

Enterobacteria phage T3 (Bacteriophage T3)

Select_allDeselect_all
CAPSA_BPT3 Major capsid protein 10A (Gene product 10A) (Gp10A) (Major head protein 10A)
CAPSB_BPT3 Minor capsid protein 10B (Minor head protein 10B)
DNLI_BPT3 DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])
DPOL_BPT3 DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 5) (Gp5)
ENRN_BPT3 Endodeoxyribonuclease 1 (EC 3.1.21.2) (Endodeoxyribonuclease I) (Endonuclease)
ENLYS_BPT3 Endolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) (T3 lysozyme)
GP73_BPT3 Protein 7.3 (Gene product 7.3) (Gp7.3) (Host specificity protein B)
EXRN_BPT3 Exodeoxyribonuclease (Exonuclease) (EC 3.1.11.3)
FIBER_BPT3 Tail fiber protein (Gene product 17) (Gp17) (Tail fiber protein gp17)
HOLIN_BPT3 Holin (Lysis protein)
PRIM_BPT3 DNA primase/helicase (EC 2.7.7.-) (EC 3.6.4.12)
RPOL_BPT3 DNA-directed RNA polymerase (EC 2.7.7.6)
SCAF_BPT3 Capsid assembly scaffolding protein (Capsid assembly protein) (Gene product 9) (Gp9) (Head ...
V192_BPT3 Gene 19.2 protein
V43_BPT3 Gene 4.3 protein
V59_BPT3 Gene 5.9 protein
VHED_BPT3 Helix-destabilizing protein (Single-stranded DNA-binding protein) (SSB protein)
V12_BPT3 Gene 1.2 protein
VRPI_BPT3 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)
Y15_BPT3 Uncharacterized gene 1.5 protein
Y195_BPT3 Uncharacterized gene 19.5 protein
Y18_BPT3 Uncharacterized gene 1.8 protein
Y16_BPT3 Uncharacterized gene 1.6 protein
Y105_BPT3 Uncharacterized gene 1.05 protein
Y37_BPT3 Uncharacterized gene 3.7 protein
Y53_BPT3 Uncharacterized gene 5.3 protein
Y51_BPT3 Uncharacterized gene 5.1 protein
Y63_BPT3 Uncharacterized gene 6.3 protein
Y65_BPT3 Uncharacterized gene 6.5 protein
Y67_BPT3 Uncharacterized gene 6.7 protein
PORTL_BPT3 Portal protein (Gene product 8) (Gp8) (Head-to-tail connector gp8) (Head-to-tail joining protein)
SPAN1_BPT3 Spanin, inner membrane subunit (i-spanin) (Gene product 18.5) (Gp18.5)
SPAN2_BPT3 Spanin, outer lipoprotein subunit (o-spanin) (Gene product 18.7) (Gp18.7) (Protein 18.7)
TERL_BPT3 Terminase, large subunit gp19 (EC 3.1.-.-) (DNA maturase B) (DNA-packaging protein B) (Gene product ...
V42_BPT3 Gene 4.2 protein
V55_BPT3 Gene 5.5 protein
V17_BPT3 Gene 1.7 protein
V57_BPT3 Gene 5.7 protein
VDMA_BPT3 DNA maturase A (DNA-packaging protein A) (GP18)
V45_BPT3 Gene 4.5 protein
V11_BPT3 Gene 1.1 protein
V193_BPT3 Gene 19.3 protein