Caveolin-mediated endocytosis of virus by host

fusion lysis permeabilisation
Virus internalization by the host cell via caveolae, which are specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane. Caveolins form the structural backbone of caveolae (CAV1/caveolin-1 (AF095593:9606) and CAV2/caveolin-2(AF035752:9606) ; CAV3/caveolin-3(AF036367:9606) in muscle cells). Internalization via caveolae is not a constitutive process but only occurs upon cell stimulation. Internalized viruses bound to their host cell receptor are delivered to the early endosome. It has been first thought that bound viruses were first taken to pH-neutral organelles in the cytoplasm called caveosomes and finally delivered to the ER, but this has been refuted in . Caveolae represent a low capacity but highly regulated pathway .

Matching UniProtKB/Swiss-Prot entries

56 entries grouped by protein (browse by keywords)

All proteins are shown (view only 49 complete proteome entries)

46 entries

Large envelope protein (L glycoprotein) (L-HBsAg) (LHB) (Large S protein) (Large surface protein) (Major surface antigen)

Select_allDeselect_all
HBSAG_HBVCJ
Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) (HBV-C) reference strain
HBSAG_HBVD3
Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979) (HBV-D) reference strain
HBSAG_HBVA1
Hepatitis B virus genotype A1 subtype adw2 (isolate Southern-Africa/Cai) (HBV-A)
HBSAG_HBVA2
Hepatitis B virus genotype A2 subtype adw (isolate Japan/Nishioka/1983) (HBV-A)
HBSAG_HBVA3
Hepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979) (HBV-A)
HBSAG_HBVA4
Hepatitis B virus genotype A2 subtype adw2 (isolate Germany/991/1990) (HBV-A)
HBSAG_HBVA5
Hepatitis B virus genotype A1 subtype adw (isolate Philippines/pFDW294/1988) (HBV-A)
HBSAG_HBVA6
Hepatitis B virus genotype A1 subtype adw2 (isolate South Africa/84/2001) (HBV-A)
HBSAG_HBVA7
Hepatitis B virus genotype A2 (isolate Japan/11D11HCCW/1998) (HBV-A)
HBSAG_HBVA8
Hepatitis B virus genotype A3 (isolate Cameroon/CMR983/1994) (HBV-A)
HBSAG_HBVA9
Hepatitis B virus genotype A3 (isolate Cameroon/CMR711/1994) (HBV-A)
HBSAG_HBVB1
Hepatitis B virus genotype B1 subtype adw (isolate Japan/pJDW233/1988) (HBV-B)
HBSAG_HBVB2
Hepatitis B virus genotype B2 (isolate Indonesia/pIDW420/1988) (HBV-B)
HBSAG_HBVB3
Hepatitis B virus genotype B2 (isolate Vietnam/9873/1997) (HBV-B)
HBSAG_HBVB4
Hepatitis B virus genotype B/C subtype adw (isolate Okinawa/pODW282/1998) (HBV-B)
HBSAG_HBVB5
Hepatitis B virus genotype B2 (isolate Vietnam/16091/1992) (HBV-B)
HBSAG_HBVB6
Hepatitis B virus genotype B2 subtype adw (isolate China/patient4/1996) (HBV-B)
HBSAG_HBVB7
Hepatitis B virus genotype B1 (isolate Japan/Yamagata-2/1998) (HBV-B)
HBSAG_HBVB8
Hepatitis B virus genotype B1 (isolate Japan/Ry30/2002) (HBV-B)
HBSAG_HBVC0
Hepatitis B virus genotype C (isolate Vietnam/3270/2000) (HBV-C)
HBSAG_HBVC1
Hepatitis B virus genotype C subtype adr (isolate Japan/Nishioka/1983) (HBV-C)
HBSAG_HBVC2
Hepatitis B virus genotype C subtype ar (isolate Japan/S-207/1988) (HBV-C)
HBSAG_HBVC3
Hepatitis B virus genotype C subtype adr (strain Japan/adr4/1983) (HBV-C)
HBSAG_HBVC4
Hepatitis B virus genotype C subtype adr (isolate Korea/Kim/1989) (HBV-C)
HBSAG_HBVC5
Hepatitis B virus genotype C subtype ad (isolate Japan/S-179/1988) (HBV-C)
HBSAG_HBVC6
Hepatitis B virus genotype C subtype adr (isolate China/NC-1/1988) (HBV-C)

Small envelope protein (S glycoprotein) (S-HBsAg) (SHB) (Small S protein) (Small surface protein)

HBSAG_HBVC7
Hepatitis B virus genotype C subtype ayw (isolate China/Tibet127/2002) (HBV-C)
HBSAG_HBVC8
Hepatitis B virus genotype C subtype adr (isolate Japan/A4/1994) (HBV-C)
HBSAG_HBVC9
Hepatitis B virus genotype C subtype ayw (isolate Australia/AustRC/1992) (HBV-C)
HBSAG_HBVD1
Hepatitis B virus genotype D subtype adw (isolate United Kingdom/adyw/1979) (HBV-D)
HBSAG_HBVD2
Hepatitis B virus genotype D (isolate France/alpha1/1989) (HBV-D)
HBSAG_HBVD4
Hepatitis B virus genotype D subtype ayw (isolate Japan/JYW796/1988) (HBV-D)
HBSAG_HBVD5
Hepatitis B virus genotype D subtype ayw (isolate Australia/AustKW/1991) (HBV-D)
HBSAG_HBVD6
Hepatitis B virus genotype D subtype ayw (isolate Italy/CI/1992) (HBV-D)
HBSAG_HBVD7
Hepatitis B virus genotype D (isolate Germany/1-91/1991) (HBV-D)
HBSAG_HBVE1
Hepatitis B virus genotype E subtype ayw4 (isolate Kou) (HBV-E)
HBSAG_HBVE2
Hepatitis B virus genotype E (isolate Cote d'Ivoire/ABI-129/2003) (HBV-E)
HBSAG_HBVE4
Hepatitis B virus genotype E (isolate Cote d'Ivoire/ABI-212/2003) (HBV-E)
HBSAG_HBVF1
Hepatitis B virus genotype F2 (isolate Brazil/w4B) (HBV-F)
HBSAG_HBVF3
Hepatitis B virus genotype F1 (isolate Argentina/sa11/2000) (HBV-F)
HBSAG_HBVF4
Hepatitis B virus genotype F2 (isolate Argentina/sa16/2000) (HBV-F)
HBSAG_HBVF6
Hepatitis B virus genotype F2 subtype adw4q (isolate Senegal/9203) (HBV-F)
HBSAG_HBVG3
Hepatitis B virus genotype G (isolate IG29227/2000) (HBV-G)
HBSAG_HBVH1
Hepatitis B virus genotype H (isolate United States/LAS2523/2002) (HBV-H)
HBSAG_HBVH2
Hepatitis B virus genotype H subtype adw4 (isolate Nicaragua/1853Nic/1997) (HBV-H)
HBSAG_HBVH3
Hepatitis B virus genotype H subtype adw4 (isolate Nicaragua/2928Nic/1997) (HBV-H)

2 entries

Genome polyprotein

Select_allDeselect_all
POLG_EC01F
Echovirus 1 (strain Human/Egypt/Farouk/1951) (E-1)
POLG_POL3L
Poliovirus type 3 (strains P3/Leon/37 and P3/Leon 12A[1]B)

8 entries

Major capsid protein VP1 (Major structural protein VP1)

Select_allDeselect_all
VP1_POVMA
Murine polyomavirus (strain A2) (MPyV) reference strain
VP1_SV40
Simian virus 40 (SV40) reference strain
VP1_POVBA
BK polyomavirus (strain AS) (BKPyV)
VP1_POVBK
BK polyomavirus (BKPyV) (Human polyomavirus 1)
VP1_POVM3
Murine polyomavirus (strain 3) (MPyV)
VP1_POVMC
Murine polyomavirus (strain Crawford small-plaque) (MPyV)
VP1_POVMK
Murine polyomavirus (strain Kilham) (MPyV) (Murine pneumotropic virus)
VP1_POVMP
Murine polyomavirus (strain P16 small-plaque) (MPyV)

Capsid protein VP1