Mimiviridae

Molecular biology

VIRION

Icosahedral capsid of 400 nm in diameter, with a symmetry between T=972 and T=1141 or T=1200 (H=19+/-1, K=19+/-1). 125 nm long closely packed fibres projecting out from the casid surface (750 nm total length). The capsid contains the internal core surrounded by an internal lipid layer. A five-fold axe display a starfish-shaped structure (pubmed)

GENOME

Monopartite, linear, dsDNA genome of of 1200 kb. Encodes for 911 ORF.

GENE EXPRESSION

REPLICATION

Matching UniProtKB/Swiss-Prot entries

905 entries grouped by protein

reorder by strain

Putative 5'(3')-deoxyribonucleotidase R824 (EC 3.1.3.-)

Putative ADP-ribosyl glycohydrolase L444 (EC 3.2.2.-)

Putative ADP-ribosyl glycohydrolase L543 (EC 3.2.2.-)

Probable asparagine synthetase

Capsid protein 1 (Capsid protein D13L)

Probable capsid protein 2

Probable capsid protein 3

Probable capsid protein 4

Putative cfxQ-like protein R730

Probable cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase)

Collagen-like protein 1

Collagen-like protein 2

Collagen-like protein 3

Collagen-like protein 4

Collagen-like protein 5

Collagen-like protein 6

Collagen-like protein 7

Putative collagenous domain-containing protein R238

Probable lanosterol 14-alpha demethylase (EC 1.14.13.70) (CYPLI) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (Sterol 14-alpha demethylase)

Cytochrome b5-like protein

Probable 7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Sterol Delta(7)-reductase)

Putative mRNA-decapping protein (EC 3.1.3.-) (Diphosphoinositol polyphosphate phosphohydrolase) (DIPP) (EC 3.6.1.52)

DNA ligase (EC 6.5.1.2) (NAD-dependent DNA ligase) (Polydeoxyribonucleotide synthase

Putative deoxynucleotide monophosphate kinase (DNK) (dNMP kinase) (EC 2.7.4.13)

DNA polymerase (EC 2.7.7.7)

Probable DNA polymerase family X (EC 2.7.7.7)

Bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS)

Putative endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV)

Probable formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase) (AP lyase) (EC 4.2.99.18)

Probable glucosamine--fructose-6-phosphate aminotransferase

Putative glutamine synthetase (EC 6.3.1.2)

Probable glutaredoxin

Probable glucosamine 6-phosphate N-acetyltransferase (EC 2.3.1.4) (Phosphoglucosamine acetylase) (Phosphoglucosamine transacetylase)

Heat shock 70 kDa protein homolog

Heat shock protein 70 homolog

Eukaryotic translation initiation factor 4E homolog (eIF-4E) (eIF4E) (mRNA cap-binding protein)

Thymidine kinase (EC 2.7.1.21)

Lon protease homolog (EC 3.4.21.-)

Mitochondrial carrier-like protein L276 (VMC1) (Viral mitochondrial carrier)

Probable mRNA-capping enzyme

Probable methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase)

Putative DNA mismatch repair protein mutS homolog L359

Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6)

NDK_MIMIVAcanthamoeba polyphaga mimivirus (APMV) reference strain

2B8P 2B8Q 3B6B 3DDI 3DKD 3EE3 3EIC 3EJM 3ELH 3EM1 3EMT 3ENA 3ETM 3EVM 3EVO 3EVW 3FBB 3FBC 3FBE 3FBF 3FC9 3FCV 3FCW 3G2X 3GP9 3GPA

Putative glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) (Peptide N-myristoyltransferase)

Putative prolyl 4-hydroxylase (4-PH) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase)

Putative poly(A) polymerase catalytic subunit (EC 2.7.7.19)

Probable DNA polymerase sliding clamp (Proliferating cell nuclear antigen homolog) (PCNA)

Phosphatidylethanolamine-binding protein homolog R644

Probable procollagen-lysine,2-oxoglutarate 5-dioxygenase (EC 1.14.11.4) (Lysyl hydroxylase) (LH)

Putative bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase)

Structural PPIase-like protein L605 (Mimicyp)

Putative tyrosine-protein phosphatase R622 (EC 3.1.3.48)

Probable Rab-related GTPase

Putative replication factor C large subunit (RFC large subunit) (Clamp loader large subunit)

Putative replication factor C small subunit R395 (RFC small subunit R395) (Clamp loader small subunit R395)

Putative replication factor C small subunit L478 (RFC small subunit L478) (Clamp loader small subunit L478)

Putative replication factor C small subunit L499 (RFC small subunit L499) (Clamp loader small subunit L499)

Putative replication factor C small subunit L510 (RFC small subunit L510) (Clamp loader small subunit L510)

Putative rhomboid protein L523 (EC 3.4.21.-)

Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large subunit)

Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small subunit)

Probable ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)

Probable ribonuclease H (RNase H) (EC 3.1.26.4)

Robin

DNA-directed RNA polymerase subunit 1 (EC 2.7.7.6)

Putative DNA-directed RNA polymerase subunit 1 inactive homolog

DNA-directed RNA polymerase subunit 2 (EC 2.7.7.6)

DNA-directed RNA polymerase subunit 5 (EC 2.7.7.6)

DNA-directed RNA polymerase subunit 6 (EC 2.7.7.6)

Protein translation factor SUI1 homolog

Cysteinyl-tRNA synthetase (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS)

Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS)

Arginyl-tRNA synthetase (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS)

Tyrosyl-tRNA synthetase (EC 6.1.1.1) (Tyrosine--tRNA ligase) (TyrRS)

TATA-box-binding protein-like (TATA-binding factor-like) (TATA-box factor-like) (TBP-like)

Putative transcription initiation factor IIB-like protein

Transcription factor S-II-related protein

Putative dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46)

DNA topoisomerase 1B (TopIB) (EC 5.99.1.2) (DNA topoisomerase type IB)

DNA topoisomerase 1 type prokaryotic (EC 5.99.1.2)

DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II)

Thioredoxin domain-containing protein R362

Thioredoxin domain-containing protein R443

Thioredoxin-like protein R548

Probable ubiquitin-conjugating enzyme E2 L460 (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)

Probable ubiquitin-conjugating enzyme E2 L709 (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)

Probable ubiquitin-conjugating enzyme E2 R521 (EC 6.3.2.19) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)

Probable bifunctional E2/E3 enzyme R795

Probable ubiquitin carboxyl-terminal hydrolase R319 (EC 3.4.19.12) (Deubiquitinating enzyme R319) (Ubiquitin thiolesterase R319) (Ubiquitin-specific-processing protease R319)

Putative ubiquitin carboxyl-terminal hydrolase L293 (EC 3.4.19.12) (Deubiquitinating enzyme L293) (Ubiquitin thiolesterase L293) (Ubiquitin-specific-processing protease L293)

Probable UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase)

Probable uracil-DNA glycosylase (UDG) (EC 3.2.2.-)

Putative UV-damage endonuclease (EC 3.-.-.-)

Uncharacterized protein R546

Putative homeobox protein R749

Putative TPR repeat-containing protein R856

Uncharacterized Bro-N domain-containing protein L2

Uncharacterized protein L3

Putative KilA-N domain-containing protein L4

Uncharacterized protein L5

Uncharacterized protein L6

Uncharacterized protein L7

Uncharacterized protein L12

Uncharacterized protein L15

Uncharacterized protein L16

Uncharacterized protein L17

Putative sel1-like repeat-containing protein L18

Uncharacterized protein L19

Uncharacterized protein L20

Putative sel1-like repeat-containing protein L21

Putative ankyrin repeat protein L22

Putative ankyrin repeat protein L23

Putative ankyrin repeat protein L25

Uncharacterized protein L26

Uncharacterized protein L27

Uncharacterized protein L28

Uncharacterized protein L30

Uncharacterized protein L31

Putative KilA-N domain-containing protein L32

Putative KilA-N domain-containing protein L33

Putative BTB/POZ domain-containing protein L35

Putative ankyrin repeat protein L36

Putative KilA-N domain-containing protein L37

Putative ankyrin repeat protein L38

Uncharacterized protein L39

Uncharacterized protein L41

Putative ankyrin repeat protein L42

Uncharacterized protein L43

Putative ankyrin repeat protein L45

Uncharacterized protein L46

Uncharacterized protein L48

Uncharacterized protein L49

Uncharacterized protein L51

Uncharacterized protein L52

Uncharacterized protein L53

Uncharacterized protein L54

Putative BTB/POZ domain-containing protein L55

Putative ankyrin repeat protein L56

Uncharacterized protein L57

Putative ankyrin repeat protein L59

Putative F-box and FNIP repeat-containing protein L60

Putative ankyrin repeat protein L62

Putative ankyrin repeat protein L63

Uncharacterized protein L64

Uncharacterized protein L65

Putative ankyrin repeat protein L66

Putative BTB/POZ domain-containing protein L67

Uncharacterized protein L68

Putative ankyrin repeat protein L72

Uncharacterized protein L74

Uncharacterized protein L75

Putative BTB/POZ domain-containing protein L76

Uncharacterized protein L77

Uncharacterized protein L78

Putative transposase L79

Putative ankyrin repeat protein L81

Uncharacterized protein L82

Uncharacterized WD repeat-containing protein L84

Putative BTB/POZ domain-containing protein L85

Putative ankyrin repeat protein L86

Uncharacterized protein L87

Putative ankyrin repeat protein L88

Putative BTB/POZ domain-containing protein L89

Uncharacterized protein L90

Putative ankyrin repeat protein L91

Putative ankyrin repeat protein L92

Putative ankyrin repeat protein L93

Uncharacterized protein L94

Uncharacterized protein L95

Putative BTB/POZ domain-containing protein L98

Putative ankyrin repeat protein L99

Putative ankyrin repeat protein L100

Uncharacterized protein L101

Uncharacterized protein L102

Putative resolvase L103

Uncharacterized protein L105

Putative BTB/POZ domain-containing protein L107

Uncharacterized protein L108

Putative ankyrin repeat protein L109

Uncharacterized protein L110

Uncharacterized protein L111

Putative ankyrin repeat protein L112

Uncharacterized protein L113

Uncharacterized protein L114

Putative helicase L115 (EC 3.6.4.-)

Uncharacterized protein L116

Uncharacterized protein L117

Putative ankyrin repeat protein L120

Putative ankyrin repeat protein L121

Putative ankyrin repeat protein L122

Uncharacterized protein L123

Putative F-box protein L126

Putative F-box protein L127

Putative GMC-type oxidoreductase L128 (EC 1.-.-.-)

Uncharacterized protein L134

Uncharacterized protein L136

Uncharacterized protein L137

Uncharacterized protein L138

Uncharacterized protein L140

Uncharacterized protein L142

Uncharacterized protein L143

Uncharacterized protein L144

Uncharacterized protein L145

Uncharacterized protein L146

Uncharacterized protein L147

Putative ankyrin repeat protein L148

Uncharacterized protein L149

Uncharacterized protein L152

Uncharacterized protein L153

Uncharacterized protein L157

Putative FNIP repeat-containing protein L162

Uncharacterized protein L163

Putative F-box protein L165

Putative F-box protein L166

Uncharacterized protein L167

Putative F-box protein L168

Uncharacterized protein L169

Putative FNIP repeat-containing protein L170

Uncharacterized protein L171

Uncharacterized protein L172

Uncharacterized protein L173

Uncharacterized protein L174

Uncharacterized protein L175

Uncharacterized protein L176

Uncharacterized protein L177

Uncharacterized protein L178

Uncharacterized protein L179

Uncharacterized protein L180

Uncharacterized protein L181

Uncharacterized protein L182

Uncharacterized protein L183

Uncharacterized protein L184

Uncharacterized protein L185

Uncharacterized protein L189

Uncharacterized protein L191

Uncharacterized protein L192

Uncharacterized glycosyltransferase L193 (EC 2.4.-.-)

Uncharacterized protein L199

Uncharacterized protein L200

Uncharacterized protein L201

Uncharacterized protein L202

Uncharacterized protein L204

Putative serine/threonine-protein kinase L205 (EC 2.7.11.1)

Putative helicase L207/L206 (EC 3.6.4.-)

Uncharacterized protein L208

Uncharacterized protein L211

Putative ankyrin repeat protein L215

Uncharacterized protein L216

Uncharacterized protein L218

Putative SET domain-containing protein L222

Uncharacterized protein L223

Uncharacterized protein L226

Uncharacterized protein L227

Uncharacterized protein L228

Uncharacterized protein L231

Putative serine/threonine-protein kinase L232 (EC 2.7.11.1)

Putative zinc protease L233 (EC 3.4.24.-)

Uncharacterized protein L234

Uncharacterized protein L236

Uncharacterized protein L237

Uncharacterized protein L242

Uncharacterized protein L243

Uncharacterized HNH endonuclease L245 (EC 3.1.-.-)

Uncharacterized protein L246

Uncharacterized HNH endonuclease L247 (EC 3.1.-.-)

Uncharacterized protein L248

Uncharacterized protein L256

Uncharacterized protein L262

Uncharacterized protein L263

Uncharacterized WD repeat-containing protein L264

Uncharacterized protein L265

Putative serine/threonine-protein kinase L268 (EC 2.7.11.1)

Uncharacterized protein L269

Uncharacterized protein L270

Putative ankyrin repeat protein L271

Putative BTB/POZ domain-containing protein L272

Putative ankyrin repeat protein L273

Uncharacterized protein L274

Putative BTB/POZ domain-containing protein L275

Uncharacterized protein L278

Putative ankyrin repeat protein L279

Uncharacterized acetyltransferase L280 (EC 2.3.1.-)

Putative FNIP repeat-containing protein L281

Uncharacterized protein L282

Putative ankyrin repeat protein L283

Putative ankyrin repeat protein L284

Uncharacterized protein L285

Putative B-type lectin protein L288

Putative ankyrin repeat protein L289

Uncharacterized protein L291

Kinesin-like protein L294

Uncharacterized protein L295

Uncharacterized protein L300

Uncharacterized protein L308

Uncharacterized protein L309

Uncharacterized protein L310

Uncharacterized protein L320

Uncharacterized protein L323

Uncharacterized protein L324

Uncharacterized protein L330

Uncharacterized protein L332

Uncharacterized protein L333

Uncharacterized protein L334

Uncharacterized protein L340

Uncharacterized WD repeat-containing protein L344

Uncharacterized protein L352

Uncharacterized protein L356

Uncharacterized protein L357

Uncharacterized protein L360

Uncharacterized protein L361

Putative ATP-dependent RNA helicase L364 (EC 3.6.4.13)

Putative ankyrin repeat protein L371

Uncharacterized glycosyltransferase L373 (EC 2.4.-.-)

Uncharacterized protein L374

Putative DNA-directed RNA polymerase subunit L376 (EC 2.7.7.6)

Putative ATP-dependent RNA helicase L377 (EC 3.6.4.13)

Uncharacterized protein L381

Uncharacterized protein L384

Uncharacterized protein L385

Putative endonuclease L386 (EC 3.1.-.-)

Uncharacterized protein L388

Uncharacterized protein L389

Putative HD domain-containing protein L394

Putative ATP-dependent RNA helicase L396 (EC 3.6.4.13)

Uncharacterized protein L397

Uncharacterized protein L399

Putative alpha/beta hydrolase L404 (EC 3.-.-.-)

Putative core protein L410

Uncharacterized protein L412

Putative F-box and FNIP repeat-containing protein L414

Putative FNIP repeat-containing protein L415

Uncharacterized protein L416

Uncharacterized protein L417

Uncharacterized protein L421

Uncharacterized protein L426

Uncharacterized protein L432

Uncharacterized protein L434

Uncharacterized protein L437

Putative TLC domain-containing protein L438

Uncharacterized protein L442

Uncharacterized protein L446 (EC 3.1.1.-)

Uncharacterized protein L448

Uncharacterized protein L451

Uncharacterized protein L452

Uncharacterized protein L454

Uncharacterized protein L456

Uncharacterized protein L461

Uncharacterized protein L462

Uncharacterized protein L471

Uncharacterized peptidase C1-like protein L477

Uncharacterized protein L479

Putative ankyrin repeat protein L483

Putative ankyrin repeat protein L484

Uncharacterized protein L485

Uncharacterized protein L487

Uncharacterized protein L488

Uncharacterized protein L490

Uncharacterized protein L491

Uncharacterized protein L492

Uncharacterized protein L494

Probable zinc-type alcohol dehydrogenase-like protein L498 (EC 1.-.-.-)

Uncharacterized protein L504

Uncharacterized protein L507

Uncharacterized protein L509

Uncharacterized protein L511

Uncharacterized protein L515

Uncharacterized protein L516

Putative BTB/POZ domain-containing protein L520

Uncharacterized protein L524

Uncharacterized protein L529

Uncharacterized protein L531

Cytochrome P450-like protein L532 (EC 1.14.14.-)

Uncharacterized protein L533

Uncharacterized protein L534

Uncharacterized protein L536

Family:	Mimiviridae
Genus:	Mimivirus