Potexvirus (taxid:12176)
VIRION

Non-enveloped, flexuous, filamentous, 470-1000 nm or more long and 12-13 nm in diameter.
GENOME
Linear ssRNA(+) genome of 5.9-7 kb in size. The 5' end is capped and 3' terminus is polyadenylated. Encodes for 5 proteins.
GENE EXPRESSION
The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs). TGB3 is expressed by leaky scanning of the TGB2 subgenomic mRNA.
ENZYMES
REPLICATION
CYTOPLASMIC
- Virus penetrates into the host cell.
- Uncoating, and release of the viral genomic RNA into the cytoplasm.
- The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
- Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
- The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
- Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
- Assembly of new virus particles.
- Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.
Host-virus interaction
Suppression of RNA silencing
Potato virus X TGBp1 protein functions as a suppressor of RNA silencing inhibiting the PTGS pathway
.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)77 entries grouped by protein
18 entries
Coat protein (Capsid protein) (CP)
12 entries
RNA replication protein (165 kDa protein) (ORF1 protein)
13 entries
Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block 1 protein) (TGBp1)
13 entries
Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
15 entries
Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
1 entry
23kDa protein (Putative 23 kDa nucleic acid binding protein)
1 entry
Uncharacterized 12.4 kDa protein
1 entry
Uncharacterized 14.1 kDa protein in ORF1 coding strand
1 entry
Uncharacterized 14.7 kDa protein in coat protein coding strand
1 entry
Uncharacterized 5.8 kDa protein
1 entry
Uncharacterized 10 kDa protein (ORF 6)
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Citrus yellow vein clearing virus taxid:1214459
Indian citrus ringspot virus (isolate Kinnow mandarin/India/K1/1996) taxid:651357
Lettuce virus X taxid:447171
Pepino mosaic virus taxid:112229
Phaius virus X taxid:457382
Pitaya virus X taxid:1176736
Protein | ModelArchive |
CP | ma-jd-viral-15990 |
Movement protein TGBp3 (Triple gene block 3 protein) | ma-jd-viral-44044 |
TGB1 | ma-jd-viral-22874 |
TGB2 | ma-jd-viral-31087 |
Plantain virus X taxid:1331744
Potexvirus alternantherae taxid:85454
Potexvirus ecsallii taxid:317027
Protein | ModelArchive |
Coat protein | ma-jd-viral-15974 |
Movement protein TGBp3 (Triple gene block 3 protein) | ma-jd-viral-08951 |
Tgb1 | ma-jd-viral-22896 |
Tgb2 | ma-jd-viral-31101 |
Senna mosaic virus taxid:1881013
Protein | ModelArchive |
CP | ma-jd-viral-15979 |
TGB1 | ma-jd-viral-22830 |
TGB2 | ma-jd-viral-31082 |
TGB3 | ma-jd-viral-49528 |
Tamus red mosaic virus taxid:1081702
Protein | ModelArchive |
Coat protein | ma-jd-viral-16004 |
Movement protein TGBp3 (Triple gene block 3 protein) | ma-jd-viral-08950 |
Tgb1 | ma-jd-viral-22852 |
Tgb2 | ma-jd-viral-31110 |