Syncytium formation induced by viral infection

Syncytia is formed by fusion of an infected cells with neighboring cells leading to the formation of multi-nucleate enlarged cells. This event is induced by surface expression of viral fusion protein that are fusogenic directly at the host cell membrane.
Syncytia canonly happen with viruses able to directly fuse at the cellular surface without the need of endocytosis.

Matching UniProtKB/Swiss-Prot entries

21 entries grouped by protein (browse by keywords)

All proteins are shown (view only 10 complete proteome entries)

Fusion glycoprotein F0

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FUS_BRSVABovine respiratory syncytial virus (strain A51908) (BRS) reference strain
FUS_HRSVBHuman respiratory syncytial virus B (strain B1) reference strain

Fusion glycoprotein F0 (Protein F)

FUS_BRSVCBovine respiratory syncytial virus (strain Copenhagen) (BRS)
FUS_BRSVRBovine respiratory syncytial virus (strain Rb94) (BRS)
FUS_HRSVAHuman respiratory syncytial virus A (strain A2)

Fusion glycoprotein F0 (Protein F)

FUS_HRSVLHuman respiratory syncytial virus A (strain Long)
FUS_HRSVRHuman respiratory syncytial virus A (strain RSS-2)
FUS_HRSV1Human respiratory syncytial virus B (strain 18537)

Envelope glycoprotein K (Syncytial protein)

Select_all Deselect_all  
GK_EHV1BEquine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain
GK_GAHVMGallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease ... reference strain

Envelope glycoprotein K

GK_HHV11Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain
GK_HHV2HHuman herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain
GK_PSHV1Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) ... reference strain
GK_VZVDVaricella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain
GK_EHV1KEquine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)
GK_HHV1KHuman herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)
GK_HHV1MHuman herpesvirus 1 (strain MP) (HHV-1) (Human herpes simplex virus 1)
GK_HHV1RHuman herpesvirus 1 (strain R15) (HHV-1) (Human herpes simplex virus 1)
GK_HHV19Human herpesvirus 1 (strain R19) (HHV-1) (Human herpes simplex virus 1)
GK_SUHVKSuid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))
GK_VZVOVaricella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)