Human immunodeficiency virus 1

Molecular biology

Enveloped, spherical to pleomorphic in shape, 80-100 nm in diameter. Mature capsid contains 1572 capsid proteins.

Monopartite, linear, dimeric, ssRNA(+) genome of 9,75 kb, with a 5’-cap and a 3’poly-A tail. There are two long terminal repeats (LTRs) of about 600nt long at the 5’ and 3’ ends. The LTRs contain the U3, R, and U5 regions. There are also a primer binding site (PBS) at the 5’end and a polypurine tract (PPT) at the 3’end.

GENE EXPRESSION

The integrated provirus utilizes the promotor elements in the 5’ LTR to drive transcription. This gives rise to the unspliced full length mRNA that will serve as genomic RNA to be packaged into virions or used as a template for translation of gag and gag-(pro)pol (1 ribosomal frameshift) polyproteins. The uncompletely spliced mRNAs encode env that is cleaved into SU and TM envelope proteins, and the accessory proteins vif, vpu, and vpr. Completely spliced mRNAs encode Rev, Tat and Nef accessory proteins. Rev escorts unspliced and uncompletely spliced RNAs out of the nucleus of infected cells.

REPLICATION

NUCLEAR

Lytic replication:

  1. Virus attaches to host CD4 receptors through the SU glycoprotein (gp120), with subsequent interaction with a chemokine coreceptor.
  2. Internalization via clathrin-dependent endocytosis. TM glycoprotein (gp41) mediates dynamin-dependent fusion with the host endosomal membrane. Nucleocapsid is released into the cytoplasm, with partial uncoating.
  3. ssRNA(+) genome is copied into a linear dsDNA molecule by the reverse transcriptase.
  4. Nuclear entry of the viral dsDNA which is covalently and randomly integrated into the cell’s genome by the integrase (=provirus).
  5. Transcription of provirus by Pol II produces viral spliced and unspliced RNAs.
  6. Translation of spliced viral RNAs produces tat, rev, and nef proteins.
  7. Rev mediates nuclear export of the uncompletely spliced RNAs.
  8. Translation of unspliced viral RNAs produces Env, Gag and Gag-Pol polyproteins.
  9. Assembly of the virion at the host cellular membrane and packaging of the viral RNA genome.
  10. Budding through the plasma membrane and release of the virions.
  11. Proteolytic processing of the precursors polyproteins by viral protease and maturation of the virions.

Latent replication : replication as a provirus integrated in the host chromosome.

Reference strains

HIV-1 REFERENCE STRAIN HIV-1 subtype B strain HxB2
Sequence | Genome | Proteome

EXPERIMENTAL CLONE PNL4.3 pNL4-3 is a subtype B strain that is normally used as the reference sequence for HIV drug resistance studies. It is a recombinant (infectious) proviral clone that contains DNA from HIV isolates NY5 (5’ half) and BRU (3’ half). The site of recombination is the EcoRI site at positions 5743-5748.
Sequence | Proteome

GROUP O REFERENCE STRAIN Group O seems to be endemic and largely confined to Cameroon and neighboring countries in West Central Africa, where these viruses represent a small minority of HIV-1 strains. (Pubmed)

HIV-1 isolate ANT70
Sequence | Proteome

GROUP N REFERENCE STRAIN The group N is confined to Cameroon. (Pubmed)

HIV-1 isolate YBF30
Sequence | Proteome
GROUP M REFERENCE STRAINS

HIV-1 group M is responsible for the worlwide pandemy of AIDS. It is subdivised into 9 subtypes (A-F), and several CRF.
(Reference strains have been chosen in collaboration with Tulio de Oliveira, Bioafrica.net)

Subtype A1: HIV-1 isolate U455
Sequence | Proteome

Subtype B: HIV-1 strain HxB2
Sequence | Genome | Proteome

Subtype C: HIV-1 isolate TV001
Sequence | Proteome

Subtype D: HIV-1 isolate ELI
Sequence | Proteome

Subtype F1: HIV-1 isolate 93BR020
Sequence | Proteome

Subtype F2: HIV-1 isolate MP255
Sequence | Proteome

Subtype G: HIV-1 isolate 92BR025
Sequence | Proteome

Subtype H: HIV-1 isolate 90CF056
Sequence | Proteome

Subtype J: HIV-1 isolate SE9173
Sequence | Proteome

Subtype K: HIV-1 isolate 96CM-MP535
Sequence | Proteome

CRF01_AE: HIV-1 isolate 90CF11697
Sequence | Proteome

CRF02_AG: HIV-1 isolate 97CM.MP807
Sequence | Proteome

Epidemiology

Global map of HIV infection source WHO/UNAIDS

HIV subtypes

HIV viruses are subdivised into groups, subtypes and CRF. Groups N and O are recent and so far restricted to cameroon. The vast majority of HIV-1 strains found worldwide belongs to Group M (Major). This group is subdivised into 9 subtypes (A-F), and several CRF (circulating recombinant form).

Source Peeters, M.

Replication cycle

  1. Virus attaches to host CD4 receptors through the SU glycoprotein (gp120), with subsequent interaction with a chemokine coreceptor.
  2. Internalization via clathrin-dependent endocytosis. TM glycoprotein (gp41) mediates dynamin-dependent fusion with the host endosomal membrane. Nucleocapsid is released into the cytoplasm, with partial uncoating.
  3. ssRNA(+) genome is copied into a linear dsDNA molecule by the reverse transcriptase.
  4. Nuclear entry of the viral dsDNA which is covalently and randomly integrated into the cell’s genome by the integrase (=provirus).
  5. Transcription of provirus by Pol II produces viral spliced and unspliced RNAs.
  6. Translation of spliced viral RNAs produces tat, rev, and nef proteins.
  7. Rev mediates nuclear export of the uncompletely spliced RNAs.
  8. Translation of unspliced viral RNAs produces Env, Gag and Gag-Pol polyproteins.
  9. Assembly of the virion at the host cellular membrane and packaging of the viral RNA genome.
  10. Budding through the plasma membrane and release of the virions.
  11. Proteolytic processing of the precursors polyproteins by viral protease and maturation of the virions.

Matching UniProtKB/Swiss-Prot entries

353 entries grouped by protein (browse by keywords)

All proteins are shown (view only 180 complete proteome entries)

Envelope glycoprotein gp160 (Env polyprotein)

Select_all Deselect_all  
ENV_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
ENV_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
ENV_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
ENV_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
ENV_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
ENV_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
ENV_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
ENV_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
ENV_HV1ZHHuman immunodeficiency virus type 1 group M subtype A (isolate Z321) (HIV-1)
ENV_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
ENV_HV1B8Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)
ENV_HV1BNHuman immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)
ENV_HV1C4Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
ENV_HV1H3Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
ENV_HV1J3Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)
ENV_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
ENV_HV1KBHuman immunodeficiency virus type 1 group M subtype B (isolate KB-1/ETR) (HIV-1)
ENV_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
ENV_HV1MFHuman immunodeficiency virus type 1 group M subtype B (isolate MFA) (HIV-1)
ENV_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
ENV_HV1N5Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)

Truncated surface protein (SU) (Glycoprotein 120) (gp120)

ENV_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
ENV_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
ENV_HV1SCHuman immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
ENV_HV1S1Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
ENV_HV1S3Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
ENV_HV1W1Human immunodeficiency virus type 1 group M subtype B (isolate WMJ1) (HIV-1)
ENV_HV1W2Human immunodeficiency virus type 1 group M subtype B (isolate WMJ22) (HIV-1)
ENV_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
ENV_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
ENV_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
ENV_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
ENV_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
ENV_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
ENV_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
ENV_HV1Z6Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
ENV_HV1Z8Human immunodeficiency virus type 1 group M subtype D (isolate Z84) (HIV-1)
ENV_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
ENV_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
ENV_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
ENV_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
ENV_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
ENV_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
ENV_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
ENV_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
ENV_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
ENV_HV1Z3Human immunodeficiency virus type 1 group M subtype U (isolate Z3) (HIV-1)

Truncated surface protein (SU) (Glycoprotein 120) (gp120)

ENV_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
ENV_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Gag polyprotein (Pr55Gag)

Select_all Deselect_all  
GAG_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
GAG_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
GAG_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
GAG_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
GAG_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
GAG_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
GAG_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
GAG_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
GAG_HV1U4Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)
GAG_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
GAG_HV1B5Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
GAG_HV1C4Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
GAG_HV1J3Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)
GAG_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
GAG_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
GAG_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
GAG_HV1N5Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
GAG_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
GAG_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
GAG_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
GAG_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
GAG_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
GAG_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
GAG_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
GAG_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
GAG_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
GAG_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
GAG_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
GAG_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
GAG_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
GAG_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
GAG_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
GAG_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
GAG_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
GAG_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
GAG_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
GAG_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
GAG_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Protein Nef (3'ORF) (Negative factor) (F-protein)

Select_all Deselect_all  
NEF_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
NEF_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
NEF_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
NEF_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
NEF_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
NEF_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
NEF_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
NEF_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
NEF_HV1U4Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)
NEF_HV1ZHHuman immunodeficiency virus type 1 group M subtype A (isolate Z321) (HIV-1)
NEF_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
NEF_HV1B8Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)
NEF_HV1BNHuman immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)
NEF_HV1H3Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
NEF_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
NEF_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
NEF_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
NEF_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
NEF_HV112Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
NEF_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
NEF_HV1SCHuman immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
NEF_HV1S1Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
NEF_HV1S3Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
NEF_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
NEF_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
NEF_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
NEF_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
NEF_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
NEF_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
NEF_HV1Z6Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
NEF_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
NEF_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
NEF_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
NEF_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
NEF_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
NEF_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
NEF_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
NEF_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
NEF_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
NEF_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
NEF_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
NEF_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Gag-Pol polyprotein (Pr160Gag-Pol)

Select_all Deselect_all  
POL_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
POL_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain

pdb 1A9M  1AJV  1AJX  1AXA  1BQM  1BQN  1D4H  1D4I  1D4J  1DLO  1DW6  1EBK  1EBW  1EBY  1EBZ  1EC0  1EC1  1EC2  1EC3  1EET  1G35  1GNM  1GNN  1GNO  1HAR  1HBV  1HEF  1HEG  1HIH  1HMV  1HNI  1HNV  1HOS  1HPS  1HPZ  1HQE  1HQU  1HRH  1HTE  1HTF  1HTG  1HVI  1HVK  1HVP  1HVU  1HYS  1IKV  1IKW  1IKX  1IKY  1J5O  1KJH  1MER  1MES  1MET  1MEU  1N5Y  1N6Q  1NPA  1NPV  1NPW  1QE1  1QMC  1R0A  1RDH  1RTD  1RVL  1RVM  1RVN  1RVO  1RVP  1RVQ  1RVR  1S6P  1S6Q  1S9E  1S9G  1SBG  1SUQ  1SV5  1T03  1T05  1T7K  1TV6  1TVR  1UWB  1W5V  1W5W  1W5X  1W5Y  1YT9  1ZP8  1ZPA  1ZSF  1ZSR  2AQU  2B5J  2B6A  2BAN  2BBB  2BE2  2EXF  2G69  2HB3  2HMI  2HNZ  2HS1  2HS2  2I4D  2I4U  2I4V  2I4W  2I4X  2I5J  2IAJ  2IC3  2IDW  2IEO  2JZW  2L45  2L46  2L4L  2UXZ  2UY0  2VG5  2VG6  2VG7  2X4U  2YKM  2YKN  2ZD1  2ZE2  3AVI  3BGR  3DLK  3GGA  3GGV  3GGX  3HVT  3IG1  3IRX  3IS9  3ISN  3ITH  3JSM  3JYT  3K2P  3K4V  3KLE  3KLF  3KLG  3KLH  3KLI  3NDT  3NU3  3NU4  3NU5  3NU6  3NU9  3NUJ  3NUO  3OK9  3PSU  3QAA  3QLH  3QO9  3TKG  3TKW  3TL9  3TLH  3V4I  3V6D  3V81  3ZPS  3ZPT  3ZPU  4COE  4CP7  4CPQ  4CPR  4CPS  4CPT  4CPU  4CPW  4CPX  4DG1  4G1Q  4G8G  4G8I  4G9D  4G9F  4H4M  4H4O  4I2P  4I2Q  4ICL  4ID5  4IDK  4IFV  4IFY  4IG0  4IG3  4KFB  4KKO  4KO0  4LSL  4LSN  4MFB  4O44  4O4G  4OJR  4PQU  4PUO  4PWD  4Q0B  4QAG  4R5P  4RW4  4RW6  4RW7  4RW8  4RW9  4U8W  4WE1  4YE3  4YHQ  4ZIP  4ZLS  5AGZ  5AH6  5AH7  5AH8  5AH9  5AHA  5AHB  5AHC  5BRY  5BS4  5C24  5C25  5C42  5CYM  5CYQ  5D3G  5FDL  5HBM  5HLF  5HP1  5HRO  5I3U  5I42  5J1E  5JFP  5JFU  5JG1  5TEP  5TER 

POL_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
POL_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
POL_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
POL_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
POL_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
POL_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
POL_HV1U4Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)
POL_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
POL_HV1B5Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
POL_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
POL_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
POL_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
POL_HV1N5Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
POL_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
POL_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
POL_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
POL_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
POL_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
POL_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
POL_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
POL_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
POL_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
POL_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
POL_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
POL_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
POL_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
POL_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
POL_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
POL_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
POL_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
POL_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
POL_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
POL_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
POL_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Protein Rev (ART/TRS) (Anti-repression transactivator) (Regulator of expression of viral proteins)

Select_all Deselect_all  
REV_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
REV_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
REV_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
REV_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
REV_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
REV_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
REV_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
REV_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
REV_HV1U4Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)
REV_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
REV_HV1C4Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
REV_HV1H3Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
REV_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
REV_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
REV_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
REV_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
REV_HV112Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
REV_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
REV_HV1SCHuman immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
REV_HV1S1Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
REV_HV1S3Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
REV_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
REV_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
REV_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
REV_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
REV_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
REV_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
REV_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
REV_HV1Z6Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
REV_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
REV_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
REV_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
REV_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
REV_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
REV_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
REV_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
REV_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
REV_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
REV_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
REV_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
REV_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Protein Tat (Transactivating regulatory protein)

Select_all Deselect_all  
TAT_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
TAT_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
TAT_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
TAT_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
TAT_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
TAT_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
TAT_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
TAT_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
TAT_HV1U4Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)
TAT_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
TAT_HV1C4Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
TAT_HV1H3Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
TAT_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
TAT_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
TAT_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
TAT_HV112Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
TAT_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
TAT_HV1SCHuman immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
TAT_HV1S1Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
TAT_HV1S3Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
TAT_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
TAT_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
TAT_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
TAT_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
TAT_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
TAT_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
TAT_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
TAT_HV1Z6Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
TAT_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
TAT_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
TAT_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
TAT_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
TAT_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
TAT_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
TAT_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
TAT_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
TAT_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
TAT_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
TAT_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
TAT_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Virion infectivity factor (Vif) (SOR protein)

Select_all Deselect_all  
VIF_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
VIF_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
VIF_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
VIF_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
VIF_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
VIF_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
VIF_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
VIF_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
VIF_HV1U4Human immunodeficiency virus type 1 group M subtype A (isolate U455) (HIV-1)
VIF_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
VIF_HV1B5Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
VIF_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
VIF_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)

Truncated virion infectivity factor (Vif) (SOR protein)

VIF_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
VIF_HV1NAHuman immunodeficiency virus type 1 group M subtype B (isolate N1T-A) (HIV-1)
VIF_HV1N5Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
VIF_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
VIF_HV112Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
VIF_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
VIF_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
VIF_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
VIF_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
VIF_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
VIF_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
VIF_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
VIF_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
VIF_HV1Z6Human immunodeficiency virus type 1 group M subtype D (isolate Z6) (HIV-1)
VIF_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
VIF_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
VIF_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
VIF_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
VIF_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
VIF_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
VIF_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
VIF_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
VIF_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
VIF_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
VIF_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
VIF_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Protein Vpr (R ORF protein) (Viral protein R)

Select_all Deselect_all  
VPR_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
VPR_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
VPR_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
VPR_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
VPR_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
VPR_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
VPR_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
VPR_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
VPR_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
VPR_HV1B5Human immunodeficiency virus type 1 group M subtype B (isolate BH5) (HIV-1)
VPR_HV1H3Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
VPR_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
VPR_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
VPR_HV1N5Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)
VPR_HV1OYHuman immunodeficiency virus type 1 group M subtype B (isolate OYI) (HIV-1)
VPR_HV112Human immunodeficiency virus type 1 group M subtype B (isolate PCV12) (HIV-1)
VPR_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
VPR_HV1SCHuman immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
VPR_HV1S3Human immunodeficiency virus type 1 group M subtype B (isolate SF33) (HIV-1)
VPR_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
VPR_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
VPR_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
VPR_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
VPR_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
VPR_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
VPR_HV1MPHuman immunodeficiency virus type 1 group M subtype F2 (isolate MP255) (HIV-1)
VPR_HV1M2Human immunodeficiency virus type 1 group M subtype F2 (isolate MP257) (HIV-1)
VPR_HV19NHuman immunodeficiency virus type 1 group M subtype G (isolate 92NG083) (HIV-1)
VPR_HV1SEHuman immunodeficiency virus type 1 group M subtype G (isolate SE6165) (HIV-1)
VPR_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
VPR_HV1V9Human immunodeficiency virus type 1 group M subtype H (isolate VI991) (HIV-1)
VPR_HV1S9Human immunodeficiency virus type 1 group M subtype J (isolate SE9173) (HIV-1)
VPR_HV1S2Human immunodeficiency virus type 1 group M subtype J (isolate SE9280) (HIV-1)
VPR_HV196Human immunodeficiency virus type 1 group M subtype K (isolate 96CM-MP535) ...
VPR_HV197Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) ...
VPR_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
VPR_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)

Protein Vpu (U ORF protein) (Viral protein U)

Select_all Deselect_all  
VPU_HV1MAHuman immunodeficiency virus type 1 group M subtype A (isolate MAL) (HIV-1) reference strain
VPU_HV1B1Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) reference strain
VPU_HV1BRHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) reference strain
VPU_HV1H2Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) reference strain
VPU_HV193Human immunodeficiency virus type 1 group M subtype F1 (isolate 93BR020) (HIV-1) reference strain
VPU_HV1VIHuman immunodeficiency virus type 1 group M subtype F1 (isolate VI850) (HIV-1) reference strain
VPU_HV1ANHuman immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1) reference strain
VPU_HV1MVHuman immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1) reference strain
VPU_HV1A2Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1)
VPU_HV1B8Human immunodeficiency virus type 1 group M subtype B (isolate BH8) (HIV-1)
VPU_HV1BNHuman immunodeficiency virus type 1 group M subtype B (isolate BRVA) (HIV-1)
VPU_HV1C4Human immunodeficiency virus type 1 group M subtype B (isolate CDC-451) (HIV-1)
VPU_HV1H3Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
VPU_HV1J3Human immunodeficiency virus type 1 group M subtype B (isolate JH32) (HIV-1)
VPU_HV1JRHuman immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
VPU_HV1LWHuman immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)
VPU_HV1MNHuman immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
VPU_HV1RHHuman immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3) (HIV-1)
VPU_HV1SCHuman immunodeficiency virus type 1 group M subtype B (isolate SC) (HIV-1)
VPU_HV1S1Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1)
VPU_HV1Y2Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)
VPU_HV1B9Human immunodeficiency virus type 1 group M subtype B (strain 89.6) (HIV-1)
VPU_HV192Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025) (HIV-1)
VPU_HV1ETHuman immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
VPU_HV1ELHuman immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)
VPU_HV1NDHuman immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
VPU_HV1Z2Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) ...
VPU_HV190Human immunodeficiency virus type 1 group M subtype H (isolate 90CF056) (HIV-1)
VPU_HV1Z3Human immunodeficiency virus type 1 group M subtype U (isolate Z3) (HIV-1)
VPU_HV1YBHuman immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)
VPU_HV1YFHuman immunodeficiency virus type 1 group N (isolate YBF30) (HIV-1)