Tectiviridae

VIRION

Non enveloped, icosahedral virion with a pseudo T=25 symmetry. Virion size is about 66 nm with apical spikes of 20 nm. The capsid encloses a inner membrane vesicle within which the genomic DNA is coiled.

GENOME

Linear, dsDNA genome of about 15 kb flanked by inverted repeats. Encodes for 30 ORFs. Replication is protein-primed.

GENE EXPRESSION

Genes are transcribed by operons.

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its spike protein P2. As a result, a protein complex composed of P2, P5, P31 and a part of the capsid (p3) is released, which produces a hole in the capsid.
  2. Internal phage membrane transforms into a tubular structure that protrudes through the hole in the capsid and penetrates the host outer membrane and peptidoglycan layer, to fuse with host plasma membrane, releasing the viral DNA into cytoplasm.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA.
  5. Transcription and translation of late genes.
  6. Capsid proteins polymerize around a lipoprotein vesicle translocated in the cytoplasm by virion assembly factors.
  7. Genomic DNA is packaged in new virions.
  8. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

25 entries grouped by strain (browse by keywords)

25 entries

Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

Select_all Deselect_all  
CAPSD_BPPRDMajor capsid protein P3 (Protein P3)
DPOL_BPPRDDNA-directed DNA polymerase (EC 2.7.7.7) (Protein P1)
P2_BPPRDAdsorption protein P2 (Protein P2)
P5_BPPRDSpike protein P5 (Protein P5)
TERM_BPPRDDNA terminal protein (Protein P8)
VLYS_BPPRDLysozyme (EC 3.2.1.17) (Lytic enzyme) (Muramidase) (Protein P15)
VP06_BPPRDProtein P6
VP07_BPPRDTransglycosylase (EC 4.2.2.-) (Protein P7)
VP09_BPPRDDNA packaging protein (Protein P9)
VP10_BPPRDProtein P10
VP11_BPPRDInfectivity protein P11
VP12_BPPRDSingle-stranded DNA-binding protein (Protein P12)
VP16_BPPRDProtein P16 (GpS) (Protein S)
VP17_BPPRDProtein P17
VP18_BPPRDProtein P18 (GpM) (Protein M)
VP19_BPPRDProtein P19
VP20_BPPRDProtein P20
VP22_BPPRDProtein P22 (GpK) (Protein K)
VP30_BPPRDMinor capsid protein P30 (Protein P) (GpP)
VP31_BPPRDPenton protein P31 (GpC) (Protein C)
VP32_BPPRDProtein P32
VP33_BPPRDProtein P33
VP34_BPPRDProtein P34 (Protein O) (GpO)
VP35_BPPRDProtein P35 (Holin)
YPI_BPPRDPutative uncharacterized 4.5 kDa protein in genes IX-XX intergenic region (ORFi)