Molecular biology

VIRION

No true capsid. The dsRNA genome is encapsulated along with the viral replicase enzyme within host-derived lipid pleomorphic vesicles (50-80nm in diameter).

GENOME

Linear dsRNA genome of 9-13kb, encodes one or two ORFs (ORFB, and eventually ORFA). The 3’end is polyadenylated. The genome only encodes non-structural proteins.
May also contain additional satellite dsRNAs.

GENE EXPRESSION

ORFB (and if present, ORFA) encodes a polyprotein that is proteolytically processed.

REPLICATION

CYTOPLASMIC

Poorly understood. The virus never leaves its host and probably replicates in the host derived lipid pleomorphic vesicles. Transmission is probably dependent on host hyphal anastomosis.