Barnaviridae

VIRION

Non-enveloped, bacilliform with a T=1 icosahedral symmetry, about 50 nm length and 20 nm large.

GENOME

Linear, ssRNA(+) genome of 4 kb. The genome contains four major and three minor ORFs.

GENE EXPRESSION

Genomic RNA serves as both the genome and viral messenger RNA. ORF2 is a polyprotein which is possibly auto-cleaved by the ORF2 viral protease. ORF3 encodes the RNA dependent RNA polymerase and may be translated by ribosomal frameshifting as an ORF2-ORF3 polyprotein. The single capsid protein (ORF4) is translated from a subgenomic RNA.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Genomic RNA is translated to produce replication proteins.
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Subgenomic RNA translation gives rise to the capsid protein precursor.
  7. Assembly of new virus particles.

Matching UniProtKB/Swiss-Prot entries

4 entries grouped by strain (browse by keywords)

4 entries

Mushroom bacilliform virus (isolate Australia/AUS LF-1) (MBV) reference strain

Select_all Deselect_all  
CAPSD_MBVLFCapsid protein (CP) (Coat protein)
ORF1_MBVLFUncharacterized protein ORF1
PTASE_MBVLFPutative serine protease (EC 3.4.21.-)
RDRP_MBVLFRNA-directed RNA polymerase (EC 2.7.7.48)