Allexivirus

VIRION

Non-enveloped, flexuous, filamentous, 800 nm long and 12 nm in diameter.

GENOME

Linear ssRNA(+) genome of 9 kb in size. The 3’ terminus is polyadenylated. Encodes for 6 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are presumably transcribed as monocistronic subgenomic mRNAs (sgRNAs).

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5’-proximal ORF).
  4. Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Matching UniProtKB/Swiss-Prot entries

6 entries grouped by strain (browse by keywords)

6 entries

Shallot virus X (ShVX) reference strain

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CAPSD_SHVXCapsid protein (CP) (Coat protein)
ORF4_SHVXUncharacterized ORF4 protein (42 kDa protein)
RDRP_SHVXRNA replication protein (194 kDa protein)
TGB1_SHVXMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_SHVXMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
VNBP_SHVX14.7 kDa protein (Putative nucleic acid-binding protein)