Potexvirus

VIRION

Non-enveloped, flexuous, filamentous, 470-1000 nm or more long and 12-13 nm in diameter.

GENOME

Linear ssRNA(+) genome of 5.9-7 kb in size. The 5’ end is capped and 3’ terminus is polyadenylated. Encodes for 5 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs). TGB3 is expressed by leaky scanning of the TGB2 subgenomic mRNA.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5’-proximal ORF).
  4. Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Host-virus interaction

Suppression of RNA silencing

Potato virus X TGBp1 protein functions as a suppressor of RNA silencing inhibiting the PTGS pathway .

Matching UniProtKB/Swiss-Prot entries

71 entries grouped by strain (browse by keywords)

All proteins are shown (view only 58 complete proteome entries)

5 entries

Potato virus X (strain X3) (PVX) reference strain

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CAPSD_PVXX3Coat protein (Capsid protein) (CP)
RDRP_PVXX3RNA replication protein (165 kDa protein) (ORF1 protein)
TGB1_PVXX3Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_PVXX3Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVXX3Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

7 entries

Papaya mosaic potexvirus (PMV)

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CAPSD_PMVCoat protein (Capsid protein) (CP)
RDRP_PMVRNA replication protein (176 kDa protein) (ORF1 protein)
TGB1_PMVMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_PMVMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PMVMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
Y14K_PMVUncharacterized 14.1 kDa protein in ORF1 coding strand
Y15K_PMVUncharacterized 14.7 kDa protein in coat protein coding strand

6 entries

Narcissus mosaic virus (NMV)

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CAPSD_NMVCoat protein (Capsid protein) (CP)
RDRP_NMVRNA replication protein (186 kDa protein) (ORF1 protein)
TGB1_NMVMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_NMVMovement protein TGB2 (14 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_NMVMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
YOR6_NMVUncharacterized 10 kDa protein (ORF 6)

5 entries

Foxtail mosaic virus

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CAPSD_FXMVCoat protein (Capsid protein) (CP)
RDRP_FXMVRNA replication protein (152 kDa protein) (ORF1 protein)
TGB1_FXMVMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_FXMVMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_FXMVMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Plantago asiatica mosaic potexvirus (P1AMV)

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CAPSD_P1AMVCoat protein (Capsid protein) (CP)
RDRP_P1AMVRNA replication protein (156 kDa protein) (ORF1 protein)
TGB1_P1AMVMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_P1AMVMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_P1AMVMovement protein TGBp3 (13 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Potato virus X (PVX)

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CAPSD_PVXCoat protein (Capsid protein) (CP)
RDRP_PVXRNA replication protein (165 kDa protein) (ORF1 protein)
TGB1_PVXMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_PVXMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVXMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Potato virus X (strain CP) (PVX)

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CAPSD_PVXCPCoat protein (Capsid protein) (CP)
RDRP_PVXCPRNA replication protein (165 kDa protein) (ORF1 protein)
TGB1_PVXCPMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_PVXCPMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVXCPMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Potato virus X (strain HB) (PVX)

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CAPSD_PVXHBCoat protein (Capsid protein) (CP)
RDRP_PVXHBRNA replication protein (165 kDa protein) (ORF1 protein)
TGB1_PVXHBMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_PVXHBMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_PVXHBMovement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

Strawberry mild yellow edge-associated virus (SMYEaV)

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CAPSD_SMYEACoat protein (Capsid protein) (CP)
RDRP_SMYEARNA replication protein (150 kDa protein) (ORF1 protein)
TGB1_SMYEAMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_SMYEAMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_SMYEAMovement protein TGBp3 (8.1 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

White clover mosaic virus (strain M) (WCMV)

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CAPSD_WCMVMCoat protein (Capsid protein) (CP)
RDRP_WCMVMRNA replication protein (147 kDa protein) (ORF1 protein)
TGB1_WCMVMMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_WCMVMMovement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_WCMVMMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

5 entries

White clover mosaic virus (strain O) (WCMV)

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CAPSD_WCMVOCoat protein (Capsid protein) (CP)
RDRP_WCMVORNA replication protein (147 kDa protein) (ORF1 protein)
TGB1_WCMVOMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_WCMVOMovement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)
TGB3_WCMVOMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

3 entries

Clover yellow mosaic virus (CYMV)

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CAPSD_CYMVCoat protein (Capsid protein) (CP)
TGB3_CYMVMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)
Y5K_CYMVUncharacterized 5.8 kDa protein

3 entries

Cymbidium mosaic virus (strain Singapore)

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CAPSD_CMVSICoat protein (Capsid protein) (CP)
TGB3_CMVSIMovement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)
Y12K_CMVSIUncharacterized 12.4 kDa protein

3 entries

Lily virus X

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CAPSD_LVXCoat protein (Capsid protein) (CP)
TGB1_LVXMovement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor ...
TGB2_LVXMovement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)

2 entries

Potato virus X (strain Xc) (PVX)

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CAPSD_PVXXCCoat protein (Capsid protein) (CP)
TGB3_PVXXCMovement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

1 entry

Potato aucuba mosaic virus (PAMV)


CAPSD_PAMVCoat protein (Capsid protein) (CP)

1 entry

Potato virus X (strain UK3) (PVX)


CAPSD_PVXU3Coat protein (Capsid protein) (CP)