Hp1virus

VIRION

Non-enveloped, head-tail structure. Heads are about 60 nm in diameter and tails 135×18 nm. The tail is contractile, has 6 long terminal fibers, 6 short spikes and a small base plate. The capsid has an elongated icosahedral symmetry T=7, composed of 72 capsomers (60 hexamers and 12 pentamers). Upon contraction, the tail sheath becomes loose and slides along the tail core.

GENOME

Linear, dsDNA genome of about 33 kb, encoding for about 45 proteins.

GENE EXPRESSION

Genes are transcribed by operons.

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to the target cell through its tail fibers.
  2. Viral exolysin degrades cell wall locally
  3. Ejection of the viral DNA into host cell cytoplasm by contraction of the tail sheath.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by rolling circle. Linear molecules are generated from closed circular monomer product by viral terminase proteins.
  6. Transcription and translation of late genes.
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fibers assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

41 entries grouped by strain (browse by keywords)

41 entries

Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

Select_all Deselect_all  
BP29_BPHC1Putative baseplate protein gp29 (Gene 29 protein) (Gp29)
CAPSD_BPHC1Major capsid protein (Gene product 18) (gp18) (Major head protein) (ORF18)
FIB31_BPHC1Probable tail fiber protein (Gene product 31) (gp31) (ORF31)
HOLI_BPHC1Holin
LYS_BPHC1Lysozyme (EC 3.2.1.17) (Endolysin) (Lysis protein) (Muramidase)
PORTL_BPHC1Probable portal protein (ORF15)
REP_BPHC1Replication protein (EC 3.1.-.-)
RPC1_BPHC1Repressor protein CI
SCAF_BPHC1Capsid assembly scaffolding protein (Gene product 17) (Gp17) (Head ...
TAIL1_BPHC1Putative tail protein gp30 (Gene product 30) (gp30)
TMP_BPHC1Probable tape measure protein (TMP) (Gene product 27) (gp27)
VCOX_BPHC1Regulatory protein cox
VINT_BPHC1Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VPL_BPHC1Probable head completion/stabilization protein (ORF20)
VPM_BPHC1Probable terminase, endonuclease subunit (ORF19)
VPP_BPHC1Probable terminase, ATPase subunit (ORF16)
YO01_BPHC1Uncharacterized 23.2 kDa protein in int-C1 intergenic region (ORF1)
YO02_BPHC1Uncharacterized 7.9 kDa protein in int-C1 intergenic region (ORF16) (ORF2)
YO03_BPHC1Uncharacterized 8.9 kDa protein in int-C1 intergenic region (ORF17) (ORF3)
YO04_BPHC1Uncharacterized 8.9 kDa protein in int-C1 intergenic region (ORF18) (ORF4)
YO05_BPHC1Uncharacterized 19.2 kDa protein in cox-rep intergenic region (ORF21) (ORF5)
YO06_BPHC1Uncharacterized 14.1 kDa protein in cox-rep intergenic region (ORF22) (ORF6)
YO07_BPHC1Uncharacterized 7.3 kDa protein in cox-rep intergenic region (ORF23) (ORF7)
YO08_BPHC1Uncharacterized 10.8 kDa protein in cox-rep intergenic region (ORF24) (ORF8)
YO09_BPHC1Uncharacterized 9.7 kDa protein in cox-rep intergenic region (ORF25) (ORF9)
YO10_BPHC1Uncharacterized 11.1 kDa protein in rep-hol intergenic region (ORF10)
YO11_BPHC1Uncharacterized 8.3 kDa protein in rep-hol intergenic region (ORF11)
YO12_BPHC1Uncharacterized 18.2 kDa protein in rep-hol intergenic region (ORF12)
YO13_BPHC1Uncharacterized adenine-specific methylase (EC 2.1.1.72) (ORF13)
YO14_BPHC1Uncharacterized 14.9 kDa protein in rep-hol intergenic region (ORF14)
YO21_BPHC1Uncharacterized 19.2 kDa protein in rep-hol intergenic region (ORF21)
YO22_BPHC1Uncharacterized 26.0 kDa protein in rep-hol intergenic region (ORF22)
YO23_BPHC1Putative tail sheath protein (ORF23)
YO24_BPHC1Putative tail tube protein (ORF24)
YO25_BPHC1Uncharacterized 13.1 kDa protein in lys 3'region (ORF25)
YO26_BPHC1Uncharacterized 11.3 kDa protein in lys 3'region (ORF26)
YO28_BPHC1Uncharacterized 12.7 kDa protein in lys 3'region (ORF28)
YO32_BPHC1Uncharacterized 23.3 kDa protein in lys 3'region (ORF32)
YO33_BPHC1Uncharacterized 28.3 kDa protein in lys 3'region (ORF33)
YO34_BPHC1Uncharacterized 20.8 kDa protein in lys 3'region (ORF34)
YO35_BPHC1Uncharacterized 58.7 kDa protein in lys 3'region (ORF35)