Luteoviridae

VIRION

Non-enveloped, spherical virion about 25-30 nm in diameter with T=3 icosahedral symmetry composed of 180 CP proteins.

GENOME

Monopartite, linear, ssRNA(+) genome of 5.3-5.7 kb. Poleroviruses and enamoviruses have a VPg bound at the 5’ end. There is no poly(A) tail or tRNA-like structure at the 3’ end.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The viral polymerase is expressed by a ribosomal frameshifting at the end of ORF1.

Depending on the genus, several proteins can be produced by Leaky scanning. Suppression of termination of the CP stop codon produces CP-RTD (CP extended), the capsid subunit essential for aphid transmission.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA ORF1 and ORF2 are translated to produce the RdRp fusion protein.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the 3’ coterminal sgRNAs. Traduction of these sgRNAs yields the capsid, CP-RTD and movement proteins.
  7. Virus assembly.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Polerovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation . Enamovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation Barley yellow dwarf virus protein P6 acts as a suppressor of RNA silencing

Matching UniProtKB/Swiss-Prot entries

49 entries grouped by strain (browse by keywords)

All proteins are shown (view only 33 complete proteome entries)

8 entries

Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain

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CAPSD_PLRV1Major capsid protein (Coat protein) (CP)
MCAPS_PLRV1Minor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)
MVP_PLRV1Movement protein (MP) (17 kDa protein)
P0_PLRV1Suppressor of silencing P0 (28 kDa protein) (Protein ORF0)
P1_PLRV1Protein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1)
P6_PLRV1Uncharacterized protein P6 (ORF6 protein)
RAP1_PLRV1Replication-associated protein (Rap1)
RDRP_PLRV1Protein P1-P2

6 entries

Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

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CAPSD_BYDVPMajor capsid protein (Coat protein) (CP)
MCAPS_BYDVPMinor capsid protein (P74) (Readthrough protein) (RT protein)
MVP_BYDVPMovement protein (MP) (17 kDa protein)
ORF6_BYDVPUncharacterized protein ORF6
ORF7_BYDVPUncharacterized protein ORF7
RDRP_BYDVPPutative RNA-directed RNA polymerase (EC 2.7.7.48)

5 entries

Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain

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CAPSD_PEMVWMajor capsid protein (Coat protein) (CP)
MCAPS_PEMVWMinor capsid protein P3-RTD (Readthrough protein) (RT protein)
P0_PEMVWSuppressor of silencing P0 (ORF0 protein)
P1_PEMVWProtein P1 (Genome-linked protein precursor) (ORF1 protein)
RDRP_PEMVWProtein P1-P2

8 entries

Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

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CAPSD_PLRVWMajor capsid protein (Coat protein) (CP)
MCAPS_PLRVWMinor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)
MVP_PLRVWMovement protein (MP) (17 kDa protein)
P0_PLRVWSuppressor of silencing P0 (28 kDa protein) (Protein ORF0)
P1_PLRVWProtein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1)
P6_PLRVWUncharacterized protein P6 (ORF6 protein)
RAP1_PLRVWReplication-associated protein (Rap1)
RDRP_PLRVWProtein P1-P2

6 entries

Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1)

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CAPSD_TYYVFMajor capsid protein (Coat protein) (CP)
MCAPS_TYYVFMinor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)
MVP_TYYVFMovement protein (MP) (20 kDa protein)
P0_TYYVFSuppressor of silencing P0 (29 kDa protein) (Protein ORF0)
P1_TYYVFProtein P1 (66.2 kDa protein) (Genome-linked protein precursor) (Protein ORF1)
RDRP_TYYVFProtein P1-P2

3 entries

Barley yellow dwarf virus (isolate MAV-PS1) (BYDV)

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CAPSD_BYDV1Major capsid protein (Coat protein) (CP)
MVP_BYDV1Movement protein (MP) (17 kDa protein)
RDRP_BYDV1Putative RNA-directed RNA polymerase (EC 2.7.7.48)

3 entries

Barley yellow dwarf virus (isolate P-PAV) (BYDV)

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CAPSD_BYDVRMajor capsid protein (Coat protein) (CP)
MVP_BYDVRMovement protein (MP) (17 kDa protein)
RDRP_BYDVRPutative RNA-directed RNA polymerase (EC 2.7.7.48)

2 entries

Barley yellow dwarf virus (isolate NY-RPV) (BYDV)

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CAPSD_BYDVNMajor capsid protein (Coat protein) (CP)
MVP_BYDVNMovement protein (MP) (17 kDa protein)

2 entries

Bean leafroll virus (BLRV)

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CAPSD_BLRVMajor capsid protein (Coat protein) (CP)
MVP_BLRVMovement protein (MP) (16 kDa protein)

2 entries

Potato leafroll virus (PLrV)

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CAPSD_PLRVMajor capsid protein (Coat protein) (CP)
MVP_PLRVMovement protein (MP) (17 kDa protein) (MP17)

2 entries

Potato leafroll virus (strain Potato/Canada/Rowhani/1979) (PLrV)

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CAPSD_PLRVRMajor capsid protein (Coat protein) (CP)
MVP_PLRVRMovement protein (MP) (17 kDa protein)

1 entry

Barley yellow dwarf virus (isolate MAV) (BYDV)


CAPSD_BYDVMMajor capsid protein (Coat protein) (CP)

1 entry

Beet western yellows virus (isolate GB1) (BWYV)


MVP_BWYVGMovement protein (MP) (20 kDa protein)