Turriviridae

VIRION

Icosahedral T=31d capsid, 74 nm in diameter, composed of 1200 P1 (spike) and 60 P2 (capsid) proteins. The 12 five-fold vertices have turret-like appendages expanding 13nm above the capsid shell. The capsid encloses an internal lipid membrane.

GENOME

Linear dsDNA genome of 17 kb.

GENE EXPRESSION

The genome encodes 36 ORFs.

REPLICATION

CYTOPLASMIC

  1. Adsorption: the virus attaches to target cell
  2. Injection: viral DNA is injected in host cell cytoplasm
  3. Transcription and translation of early genes
  4. Replication of genomic DNA
  5. Transcription and translation of late genes
  6. Genomic DNA is packaged in new virions
  7. Mature virions are released from the cell by budding through pyramid-like protrusions.