Potyvirus

VIRION

Non-enveloped, flexuous, filamentous, of 720-850 nm long and 12-15 nm in diameter. Symmetry helical. Presence of characteristic inclusion bodies within infected plant cells.

GENOME

Monopartite, linear, ssRNA(+) genome of 10 kb in size. 3’ terminus has a poly (A) tract. 5’ terminus has a genome-linked protein (VPg).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The genomic RNA is translated into polyproteins which are subsequently processed by the action of three viral-encoded proteinases into functional products. P3N-PIPO is expressed by polymerase slippage mechanism from the P3 ORF and probably acts as a movement protein .

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce a polyprotein which is processed by viral proteases into the RdRp protein and structural proteins.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Virus assembly in the cytoplasm.
  7. Viral movement protein P3N-PIPO probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Potyviruses HC-PRO functions as a suppressor of RNA silencing .

Suppression of other plant defenses

VPg is a potent inhibitor of PAP depurination of RNA, thereby suppressing one of the plant defense mechanisms .

Matching UniProtKB/Swiss-Prot entries

49 entries grouped by strain (browse by keywords)

2 entries

Potato virus Y (strain N) (PVY) reference strain

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MVP_PVYNP3N-PIPO polyprotein
POLG_PVYNGenome polyprotein

2 entries

Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))

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MVP_BCMNNP3N-PIPO polyprotein
POLG_BCMNNGenome polyprotein

2 entries

Bean yellow mosaic virus

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MVP_BYMVP3N-PIPO polyprotein
POLG_BYMVGenome polyprotein

2 entries

Beet mosaic virus (BtMV)

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MVP_BTMVP3N-PIPO polyprotein
POLG_BTMVGenome polyprotein

2 entries

Lettuce mosaic virus (strain 0 / isolate French) (LMV)

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MVP_LMV0P3N-PIPO polyprotein
POLG_LMV0Genome polyprotein

2 entries

Lettuce mosaic virus (strain E) (LMV)

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MVP_LMVEP3N-PIPO polyprotein
POLG_LMVEGenome polyprotein

2 entries

Papaya ringspot virus (strain P / mutant HA)

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MVP_PRSVHP3N-PIPO polyprotein
POLG_PRSVHGenome polyprotein

2 entries

Pea seed-borne mosaic virus (strain DPD1)

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MVP_PSBMVP3N-PIPO polyprotein
POLG_PSBMVGenome polyprotein

2 entries

Peanut mottle virus (strain M)

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MVP_PEMVMP3N-PIPO polyprotein
POLG_PEMVMGenome polyprotein

2 entries

Pepper mottle virus (isolate California) (PeMV) (PepMoV C)

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MVP_PEMVCP3N-PIPO polyprotein
POLG_PEMVCGenome polyprotein

2 entries

Plum pox potyvirus (isolate NAT) (PPV)

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MVP_PPVNAP3N-PIPO polyprotein
POLG_PPVNAGenome polyprotein

2 entries

Plum pox potyvirus (strain D) (PPV)

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MVP_PPVDP3N-PIPO polyprotein
POLG_PPVDGenome polyprotein

2 entries

Plum pox potyvirus (strain SK 68) (PPV)

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MVP_PPVSKP3N-PIPO polyprotein
POLG_PPVSKGenome polyprotein

2 entries

Potato virus A (PVA)

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MVP_PVMAP3N-PIPO polyprotein
POLG_PVMAGenome polyprotein

2 entries

Potato virus Y (strain Hungarian) (PVY)

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MVP_PVYHUP3N-PIPO polyprotein
POLG_PVYHUGenome polyprotein

2 entries

Soybean mosaic virus (strain G2) (SMV)

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MVP_SBMVGP3N-PIPO polyprotein
POLG_SBMVGGenome polyprotein

2 entries

Soybean mosaic virus (strain N) (SMV)

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MVP_SBMVNP3N-PIPO polyprotein
POLG_SBMVNGenome polyprotein

2 entries

Tobacco etch virus (TEV)

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MVP_TEVP3N-PIPO polyprotein
POLG_TEVGenome polyprotein

2 entries

Tobacco vein mottling virus (TVMV)

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MVP_TVMVP3N-PIPO polyprotein
POLG_TVMVGenome polyprotein

2 entries

Turnip mosaic virus (strain Japanese) (TuMV)

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MVP_TUMVJP3N-PIPO polyprotein
POLG_TUMVJGenome polyprotein

2 entries

Turnip mosaic virus (strain Quebec) (TuMV)

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MVP_TUMVQP3N-PIPO polyprotein
POLG_TUMVQGenome polyprotein

2 entries

Zucchini yellow mosaic virus (strain California) (ZYMV)

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MVP_ZYMVCP3N-PIPO polyprotein
POLG_ZYMVCGenome polyprotein

2 entries

Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)

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MVP_ZYMVRP3N-PIPO polyprotein
POLG_ZYMVRGenome polyprotein

2 entries

Zucchini yellow mosaic virus (strain Singapore) (ZYMV)

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MVP_ZYMVSP3N-PIPO polyprotein
POLG_ZYMVSGenome polyprotein

1 entry

Plum pox potyvirus (strain Rankovic) (PPV)


POLG_PPVRAGenome polyprotein