Phi29virus

VIRION

Non-enveloped, head-tail structure. The prolate capsid is about 45×54 nm, with a T=3, Q=5 symmetry . The tail is non-contractile and has a collar with 12 appendages attached to the neck region that are important for host cell recognition and entry. The 55 capsid (head) fibers are not always present and may have been lost in some lab strains. They may enhance the attachment of the virions onto the host cell wall.

GENOME

Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes, with a terminal protein covalently attached at the 5’ end.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription and translation of early genes
  4. Replication of genomic DNA by strand displacement by the viral DNA polymerase, formation of viral genome concatemers.
  5. Transcription and translation of late genes
  6. Assembly of empty procapsids and viral genome packaging.
  7. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

85 entries grouped by strain (browse by keywords)

All proteins are shown (view only 74 complete proteome entries)

25 entries

Bacillus phage phi29 (Bacteriophage phi-29) reference strain

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CAPSD_BPPH2Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
CAPSF_BPPH2Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein ...
DIT9_BPPH2Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
DPOL_BPPH2DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
ENLYS_BPPH2Endolysin (EC 3.2.1.17) (Gene product 15) (gp15) (Lysozyme) (Morphogenesis ...
FIB12_BPPH2Pre-neck appendage protein (Gene product 12) (gp12) (NP1) (Protein p12)
GP13_BPPH2Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13)
GP166_BPPH2Gene product 16.6 (gp16.6) (Protein p16.6)
GP167_BPPH2DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP168_BPPH2Gene product 16.8 (gp16.8) (Protein p16.8)
GP169_BPPH2Gene product 16.9 (gp16.9) (Protein p16.9)
GP17_BPPH2DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
GP1_BPPH2DNA replication protein 1 (Gene product 1) (gp1)
GP55_BPPH2Gene product 5.5 (gp5.5) (Gene product 5B) (gp5B) (Protein p5.5)
HOLIN_BPPH2Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14)
NP_BPPH2Histone-like protein p6 (Double-stranded DNA-binding protein p6) (Gene product ...
P56_BPPH2Protein p56
PKG16_BPPH2DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) ...
PORTL_BPPH2Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) ...
SCAF_BPPH2Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis ...
SSB_BPPH2Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TERM_BPPH2Primer terminal protein (TP) (DNA terminal protein) (Gene product 3) (gp3) ...
TF4_BPPH2Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
TUB11_BPPH2Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar ...

7 entries

Bacillus phage Nf (Bacteriophage Nf) reference strain

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DIT9_BPNFTail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9) ...
DPOL_BPNFDNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
NP_BPNFDouble-stranded DNA-binding protein (Gene product 6) (gp6) (Nucleoid-associated ...
SSB_BPNFSingle-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)

3 entries

Bacillus phage GA-1 (Bacteriophage GA-1) reference strain

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CAPSD_BPGA1Major capsid protein (Gene product 8) (gp8) (Major head protein)
P56_BPGA1Protein p56
SSB_BPGA1Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)

26 entries

Bacillus phage PZA (Bacteriophage PZA)

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CAPSD_BPPZAMajor capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
CAPSF_BPPZACapsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein ...
DIT9_BPPZATail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
DPOL_BPPZADNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
ENLYS_BPPZAEndolysin (EC 3.2.1.17) (Gene product 15) (gp15) (Lysozyme) (Morphogenesis ...
FIB12_BPPZAPreneck appendage protein (Gene product 12) (gp12) (Protein p12)
GP13_BPPZAMorphogenesis protein 1 (Gene product 13) (gp13) (Protein p13)
GP165_BPPZAGene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
GP166_BPPZAGene product 16.6 (gp16.6) (Protein p16.6)
GP167_BPPZADNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP168_BPPZAGene product 16.8 (gp16.8) (Protein p16.8)
GP169_BPPZAGene product 16.9 (gp16.9) (Protein p16.9)
GP17_BPPZADNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
GP1_BPPZADNA replication protein 1 (Gene product 1C) (gp1C)
GP55_BPPZAGene product 5B (gp5B) (Protein p5B)
HOLIN_BPPZAAntiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14)
NP_BPPZAHistone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded ...
P56_BPPZAProtein p56
PKG16_BPPZADNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) ...
PORTL_BPPZAPortal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) ...
SCAF_BPPZACapsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis ...
SSB_BPPZASingle-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TERM_BPPZADNA terminal protein (Gene product 3) (gp3) (Protein p3)
TF4_BPPZALate genes activator p4 (Gene product 4) (gp4) (Protein p4)
TUB11_BPPZAProximal tail tube connector protein (Gene product 11) (gp11) (Lower collar ...
VG1A_BPPZAEarly protein GP1A

25 entries

Bacillus phage phi29 (Bacteriophage phi-29)


GP165_BPPH2Gene product 16.5 (gp16.5) (Protein p16.5)

17 entries

Bacillus phage B103 (Bacteriophage B103)

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CAPSD_BPB03Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
CAPSF_BPB03Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein ...
DIT9_BPB03Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
DPOL_BPB03DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
ENLYS_BPB03Endolysin (EC 3.2.1.17) (Gene product 15) (gp15) (Lysozyme) (Morphogenesis ...
FIB12_BPB03Pre-neck appendage protein (Gene product 12) (gp12) (Late protein GP12) (NP1) ...
HOLIN_BPB03Antiholin (Gene product 14) (gp14) (Protein p14)
NP_BPB03Histone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded ...
PKG16_BPB03DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) ...
PORTL_BPB03Portal protein (Gene product 10) (gp10) (Head-to-tail connector) (Upper collar ...
SCAF_BPB03Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis ...
SSB_BPB03Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TERM_BPB03DNA terminal protein (Gene product 3) (gp3) (Protein p3)
TUB11_BPB03Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar ...
VG13_BPB03Morphogenesis protein 1 (Late protein GP13)
VG17_BPB03Early protein GP17
VG4_BPB03Late genes activator (Early protein GP4)

7 entries

Bacillus phage Nf (Bacteriophage Nf)

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TERM_BPNFDNA terminal protein (Gene product 3) (gp3) (Protein p3)
VG4_BPNFLate genes activator (Early protein GP4) (GPF)
VG85_BPNFHead fiber protein (Late protein GP8.5)

6 entries

Bacillus phage phi15 (Bacteriophage phi-15)

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GP165_BPPH5Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
GP166_BPPH5Gene product 16.6 (gp16.6) (Protein p16.6)
GP167_BPPH5DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP168_BPPH5Gene product 16.8 (gp16.8) (Protein p16.8)
GP169_BPPH5Gene product 16.9 (gp16.9) (Protein p16.9)
GP17_BPPH5DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)

1 entry

Bacillus phage M2 (Bacteriophage M2)


DPOL_BPM2DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)