Endornaviridae

VIRION

None reported. No true capsid. The dsRNA genome is encapsulated along with the viral replicase enzyme.

GENOME

Linear dsRNA genome of about 14 kb to 17.6 kb. A site specific break (nick) is found in the coding strand about 1 to 2 kb from the 5’ terminus.

GENE EXPRESSION

The genome encodes for one ORF potentially cleaved in several polypeptides.

REPLICATION

CYTOPLASMIC

  1. Virus genome is transmitted horizontally through mating or vertically from mother to daughter cells.
  2. Transcription-translation of genomic RNA produces viral RdRp and possibly other proteins.
  3. Replication occurs in cytoplasmic vesicles. Genomic (+)RNA is copied into its complementary anti-genomic RNA thereby forming new dsRNA genomes.