VIRION
Non-enveloped, head-tail structure. Head is about 60-65 nm in diameter. The tail is non-contractile, has 6 prominent tail spikes.
GENOME
Linear, dsDNA genome of about 43 kb encoding for 52 genes.
GENE EXPRESSION
REPLICATION
CYTOPLASMIC
- Adsorption: the phage attaches to the target cell through its tail fibers.
- Ejection of the viral DNA into host cell cytoplasm.
- Transcription and translation of early genes.
- Replication of genomic DNA. Transcription and translation of late genes.
- Assembly of an empty procapsid and packaging of the genome.
- Viral tail fibers assembly and viral tail assembly.
- Mature virions are released from the cell by lysis.