Secoviridae

VIRION

Non-enveloped, 25-30 nm in diameter, T=pseudo3 icosahedral capsid. The three jell rolls, which are characteristic of picornavirales capsid proteins (CP), can be present in one large CP with 3 jelly rolls domains, two CP (one large with two jelly rolls domains and one small a single domain), or three CP.

GENOME

Segmented, bipartite linear ssRNA(+) genome composed of RNA-1=6-8 kb and RNA-2=4-7 kb. Each genomic segment has a VPg linked to its 5’ end and a 3’ poly(A) tract.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and mRNA.
RNA-1 and RNA-2 are translated into two polyproteins, which are then processed into functional proteins. RNA-1 encodes proteins necessary for replication, while RNA-2 encodes one or two capsid proteins and product(s) involved in cell-to-cell movement.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Synthesis and proteolytic cleavage of the replicase polyprotein RNA-1.
  4. Replication occurs in viral factories made of membrane vesicles derived from the ER. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Assembly of new virus particles.
  7. Movement protein allows cell-to-cell movement.

Matching UniProtKB/Swiss-Prot entries

52 entries grouped by strain (browse by keywords)

All proteins are shown (view only 40 complete proteome entries)

4 entries

Tomato ringspot virus (isolate raspberry) (ToRSV) reference strain

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POL1_TORVRRNA1 polyprotein (P1)
POL2_TORVRRNA2 polyprotein (P2)
YR21_TORVRUncharacterized protein in RNA2
YR22_TORVRUncharacterized protein in RNA2

3 entries

Tomato torrado virus (isolate Solanum lycopersicum/Spain/PRIToTV0301/-) (ToTV) reference strain

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ORF1_TOTVUncharacterized protein ORF1
POL1_TOTVRNA1 polyprotein
POL2_TOTVRNA2 polyprotein

2 entries

Broad bean wilt virus 1 (strain Spinach/United States/ATCC PV-132/1963) (BBWV-1) reference strain

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POL1_BBWVSRNA1 polyprotein (Genome polyprotein B)
POL2_BBWVSRNA2 polyprotein (Genome polyprotein M)

2 entries

Cherry rasp leaf virus (isolate Potato/United States) (CRLV) reference strain

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POL1_CRLVPRNA1 polyprotein (Genome polyprotein B) (P1)
POL2_CRLVPRNA2 polyprotein (P2)

2 entries

Cowpea mosaic virus (strain SB) (CPMV) reference strain

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POL1_CPMVSRNA1 polyprotein (Genome polyprotein B) (P1)
POL2_CPMVSRNA2 polyprotein (Genome polyprotein M) (P2)

2 entries

Satsuma dwarf virus (isolate Satsuma mandarin/Japan/S-58/1977) (SDV) reference strain

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POL1_SDVS5RNA1 polyprotein (P1)
POL2_SDVS5RNA2 polyprotein (P2)

1 entry

Parsnip yellow fleck virus (isolate P-121) (PYFV) reference strain


POLG_PYFV1Genome polyprotein

1 entry

Rice tungro spherical virus (strain A) (RTSV) (Rice tungro spherical waikavirus) reference strain


POLG_RTSVAGenome polyprotein

3 entries

Beet ringspot virus (BRSV) (Tomato black ring virus (strain S))

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POL1_BRSVRNA1 polyprotein (P1)
POL2_BRSVRNA2 polyprotein (P2)
VS48_BRSVSatellite RNA 48 kDa protein

3 entries

Grapevine fanleaf virus (GFLV)

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POL1_GFLVRNA1 polyprotein (P1)
POL2_GFLVRNA2 polyprotein (P2)
VP3_GFLVProtein P3

2 entries

Arabis mosaic virus (isolate NW) (ArMV)

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POL1_ARMVNRNA1 polyprotein (P1)
POL2_ARMVNRNA2 polyprotein (P2)

2 entries

Bean-pod mottle virus (strain Kentucky G7) (BPMV)

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POL1_BPMVRNA1 polyprotein (Genome polyprotein B) (P1)
POL2_BPMVRNA2 polyprotein (Genome polyprotein M) (P2)

2 entries

Blackcurrant reversion association virus (BRAV)

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POL1_BRAVRNA1 polyprotein (P1)
POL2_BRAVRNA2 polyprotein (P2)

2 entries

Cowpea severe mosaic virus (strain DG) (CPSMV)

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POL1_CPSMVRNA1 polyprotein (Genome polyprotein B) (P1)
POL2_CPSMVRNA2 polyprotein (Genome polyprotein M) (P2)

2 entries

Cycas necrotic stunt virus (CNSV)

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POL1_CNSVRNA1 polyprotein (P1)
POL2_CNSVRNA2 polyprotein (P2)

2 entries

Grapevine chrome mosaic virus (GCMV) (Hungarian grapevine chrome mosaic virus)

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POL1_GCMVRNA1 polyprotein (P1)
POL2_GCMVRNA2 polyprotein (P2)

2 entries

Raspberry ringspot virus (strain cherry) (RpRSV)

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POL1_RRVCRNA1 polyprotein (P1)
POL2_RRVCRNA2 polyprotein (P2)

2 entries

Red clover mottle virus (RCMV)

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POL1_RCMVRNA1 polyprotein (Genome polyprotein B) (P1)
POL2_RCMVRNA2 polyprotein (Genome polyprotein M) (P2)

2 entries

Tobacco ringspot virus (TobRV) (TRSV)

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CAPSD_TRSVCapsid protein (Coat protein)
POL2_TRSVRNA2 polyprotein (P2)

1 entry

Andean potato mottle virus (APMV)


POL2_APMVRNA2 polyprotein (Genome polyprotein M) (P2)

1 entry

Arabis mosaic virus (ArMV)


VP3_ARMVProtein P3

1 entry

Arabis mosaic virus (isolate Syrah) (ArMV)


POL2_ARMVSRNA2 polyprotein (P2)

1 entry

Grapevine fanleaf virus (isolate NW) (GFLV)


POL2_GFLVNRNA2 polyprotein (P2)

1 entry

Raspberry ringspot virus (strain S) (RpRSV)


POL2_RRVSRNA2 polyprotein (P2)

1 entry

Rice tungro spherical virus (strain Vt6) (RTSV) (Rice tungro spherical waikavirus)


POLG_RTSVTGenome polyprotein

1 entry

Tobacco ringspot virus (strain Bud Blight) (TobRV) (TRSV)


POL1_TRSVBRNA1 polyprotein (P1)

1 entry

Tomato black ring virus (strain C) (TBRV)


VS48_TBRVCSatellite RNA 48 kDa protein

1 entry

Tomato black ring virus (strain E) (TBRV)


VS48_TBRVESatellite RNA 48 kDa protein

1 entry

Tomato black ring virus (strain L) (TBRV)


VS48_TBRVLSatellite RNA 48 kDa protein

1 entry

Tomato black ring virus (strain MJ) (TBRV)


POL1_TBRVMRNA1 polyprotein (P1)