Fusion of virus membrane with host cell membrane (kw:KW-1169)

image


Several viruses are able to directly fuse their membrane with cell plasma membrane without being internalized by endocytosis or macropinocytosis. These capacity confers them usualy the possibility to create cell syncytia
The fusion between viral and cellular membrane is triggered by fusion proteins. All fusion proteins are active in a trimeric conformation. Most of them are natively trimeric, some of them are dimers on the virion surface but are converted to trimers upon activation .
Fusion proteins have to be produced in an inactive state in order to avoid to trigger fusion in the Golgi or other compartments upon synthesis and transport to the cell surface. Many are activated in the trans.Golgi network or at the cell surface by proteolytic cleavage which reveals the fusion peptide.

Class I
Class II
Class III
Class IV

Fusion mechanism according to the "viral fusion pore" model of Lee K: . A different model has been described with PIV5
image

Viral molecular biology Virion
Virus entry
Virus latency
Transcription and replication
Host-virus interactions
Virus exit
Links Uniprot Keyword: KW-1169
GO ontology:GO:0019064
Virus Coronaviridae, Betacoronavirus Murine coronavirus MHV-4 and MHV-JHM
Herpesviridae
Paramyxoviridae, Morbilivirus
?Plasmaviridae
Poxviridae
Retroviridae
Tectiviridae, Tectivirus

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

223 entries grouped by strain

5 entries

Vaccinia virus (strain Copenhagen) (VACV) reference strain

Select_allDeselect_all
PG094_VACCC Entry-fusion complex protein OPG094 (EFC protein OPG094) (Myristoylated protein G9)
PG099_VACCC Entry-fusion complex protein OPG094 (EFC protein OPG094) (Protein L5)
PG107_VACCC Protein H2
PG104_VACCC Protein OPG104 (Protein J5)
PG086_VACCC Entry-fusion complex protein OPG086 (EFC protein OPG086) (Protein G3)

5 entries

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

Select_allDeselect_all
PG094_VACCW Entry-fusion complex protein OPG094 (EFC protein OPG094) (Myristoylated protein G9) (Protein F1)

pdb 8GP6

PG107_VACCW Protein OPG107

pdb 8INI

PG099_VACCW Entry-fusion complex protein OPG094 (EFC protein OPG094) (Protein F6) (Protein L5)

pdb 7YTT; 7YTU

PG104_VACCW Protein OPG104 (Protein F11) (Protein J5)
PG086_VACCW Entry-fusion complex protein OPG086 (EFC protein OPG086)

pdb 7YTT; 7YTU

5 entries

Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain

Select_allDeselect_all
PG094_VAR67 Entry-fusion complex protein OPG094 (EFC protein OPG094) (Myristoylated protein G9)
PG099_VAR67 Entry-fusion complex protein OPG094 (EFC protein OPG094) (Protein L5)
PG086_VAR67 Entry-fusion complex protein OPG086 (EFC protein OPG086) (Protein G3)
PG107_VAR67 Late protein H2
PG104_VAR67 Protein OPG104 (Protein J5)

3 entries

Fowlpox virus (strain NVSL) (FPV) reference strain

Select_allDeselect_all
J5_FOWPN Protein J5 homolog (FPV136)
PG086_FOWPN Entry-fusion complex protein OPG086 (EFC protein OPG086) (Protein FPV078) (Protein G3 homolog)
L5_FOWPN L5 homolog (Protein FPV132)

2 entries

Alcelaphine herpesvirus 1 (strain C500) (AlHV-1) (Malignant catarrhal fever virus) reference strain

Select_allDeselect_all
GH_ALHV1 Envelope glycoprotein H (gH)
GL_ALHV1 Envelope glycoprotein L (gL)

2 entries

Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4) reference strain

Select_allDeselect_all
GH_EBVA8 Envelope glycoprotein H (gH)
GL_EBVA8 Envelope glycoprotein L (gL)

pdb 6C5V

2 entries

Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) reference strain

Select_allDeselect_all
GH_EBVB9 Envelope glycoprotein H (gH)

pdb 3PHF; 5T1D; 5W0K; 7CZE; 7S07; 7S1B; 7YP1; 7YP2; 8TNN; 8TNT

GL_EBVB9 Envelope glycoprotein L (gL)

pdb 3PHF; 5T1D; 5W0K; 7CZE; 7S07; 7S1B; 7YP1; 8TNN; 8TNT

2 entries

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain

Select_allDeselect_all
GL_EHV1B Envelope glycoprotein L (gL)
GH_EHV1B Envelope glycoprotein H (gH)

2 entries

Equine herpesvirus 2 (strain 86/87) (EHV-2) reference strain

Select_allDeselect_all
GH_EHV2 Envelope glycoprotein H (gH)
GL_EHV2 Envelope glycoprotein L (gL)

2 entries

Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain

Select_allDeselect_all
GL_GAHVM Envelope glycoprotein L (gL)
GH_GAHVM Envelope glycoprotein H (gH)

2 entries

Guinea pig cytomegalovirus (strain 22122) (GPCMV) reference strain

Select_allDeselect_all
GL_GPCMV Envelope glycoprotein L (gL)
GH_GPCMV Envelope glycoprotein H (gH)

2 entries

Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) reference strain

Select_allDeselect_all
GH_HCMVA Envelope glycoprotein H (gH)

pdb 7RAM; 8TCO

GL_HCMVA Envelope glycoprotein L (gL)

pdb 7M30; 7RAM; 8TCO

2 entries

Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5) reference strain

Select_allDeselect_all
GH_HCMVM Envelope glycoprotein H (gH)

pdb 5VOB; 5VOC; 5VOD; 7LBE; 7LBF; 7LBG; 7T4Q; 7T4R; 7T4S

GL_HCMVM Envelope glycoprotein L (gL)

pdb 7LBE; 7LBF; 7LBG; 7T4Q; 7T4R; 7T4S

2 entries

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain

Select_allDeselect_all
GL_HHV11 Envelope glycoprotein L (gL)
GH_HHV11 Envelope glycoprotein H (gH)

pdb 2LQY

2 entries

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain

Select_allDeselect_all
GH_HHV2H Envelope glycoprotein H (gH)

pdb 3M1C

GL_HHV2H Envelope glycoprotein L (gL)

pdb 3M1C

2 entries

Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus) reference strain

Select_allDeselect_all
GL_HHV6U Envelope glycoprotein L (gL)
GH_HHV6U Envelope glycoprotein H (gH)

2 entries

Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic virus) reference strain

Select_allDeselect_all
GL_HHV6Z Envelope glycoprotein L (gL)
GH_HHV6Z Envelope glycoprotein H (gH)

2 entries

Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus) reference strain

Select_allDeselect_all
GH_HHV7J Envelope glycoprotein H (gH)
GL_HHV7J Envelope glycoprotein L (gL)

2 entries

Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus) reference strain

Select_allDeselect_all
GH_HHV8P Envelope glycoprotein H (gH)
GL_HHV8P Envelope glycoprotein L (gL)

pdb 7B7N

2 entries

Monkeypox virus reference strain

Select_allDeselect_all
PG094_MONPV Entry-fusion complex protein OPG094 (EFC protein OPG094)
PG099_MONPV Entry-fusion complex protein OPG094 (EFC protein OPG094) (Protein L5)

2 entries

Murid herpesvirus 1 (strain Smith) (MuHV-1) (Mouse cytomegalovirus) reference strain

Select_allDeselect_all
GH_MUHVS Envelope glycoprotein H (gH)
GL_MUHVS Envelope glycoprotein L (gL)

2 entries

Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) reference strain

Select_allDeselect_all
GL_PSHV1 Envelope glycoprotein L (gL)
GH_PSHV1 Envelope glycoprotein H (gH)

2 entries

Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri) reference strain

Select_allDeselect_all
GH_SHV21 Envelope glycoprotein H (gH)
GL_SHV21 Envelope glycoprotein L (gL)

2 entries

Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain

Select_allDeselect_all
GH_VZVD Envelope glycoprotein H (gH)
GL_VZVD Envelope glycoprotein L (gL)

1 entry

African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) reference strain

E248R_ASFB7 Inner membrane protein pE248R (pE248R)

1 entry

Avian leukosis virus subgroup A (isolate RSA) (ALV-A RSA) reference strain

ENV_ALVA Envelope glycoprotein gp95 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 85) ...

pdb 4JPR; 5H9C

1 entry

Avian metapneumovirus (isolate Canada goose/Minnesota/15a/2001) (AMPV) reference strain

FUS_AMPV1 Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Bovine respiratory syncytial virus (strain A51908) (BRS) reference strain

FUS_BRSVA Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

1 entry

Hendra virus (isolate Horse/Autralia/Hendra/1994) reference strain

FUS_HENDH Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 1WP8; 5EJB; 6ILF; 6J2F; 7KI6; 8DNR

1 entry

Human T-cell leukemia virus 1 (isolate Caribbea HS-35 subtype A) (HTLV-1) reference strain

ENV_HTL1C Envelope glycoprotein gp62 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) reference strain

ENV_HTL1A Envelope glycoprotein gp62 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 2 (HTLV-2) reference strain

ENV_HTLV2 Envelope glycoprotein gp63 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 3 (strain 2026ND) (HTLV-3) reference strain

ENV_HTL32 Envelope glycoprotein gp63 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human metapneumovirus (strain CAN97-83) (HMPV) reference strain

FUS_HMPVC Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 7UR4; 8VT3

1 entry

Human parainfluenza 2 virus (strain Toshiba) (HPIV-2) reference strain

FUS_PI2HT Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Human respiratory syncytial virus B (strain B1) reference strain

FUS_HRSVB Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening ...

1 entry

Measles virus (strain Ichinose-B95a) (MeV) (Subacute sclerose panencephalitis virus) reference strain

FUS_MEASC Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 5YXW; 5YZC; 5YZD; 9AT8

1 entry

Moloney murine leukemia virus (isolate Shinnick) (MoMLV) reference strain

ENV_MLVMS Envelope glycoprotein (Pr80env) (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein ...

pdb 1MOF

1 entry

Mouse mammary tumor virus (strain BR6) (MMTV) reference strain

ENV_MMTVB Envelope glycoprotein gp70 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 52) ...

1 entry

Mouse mammary tumor virus (strain C3H) (MMTV) reference strain

ENV_MMTVC Envelope glycoprotein gp70 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 52) ...

1 entry

Mumps virus (strain Miyahara vaccine) (MuV) reference strain

FUS_MUMPM Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 2FYZ

1 entry

Murine pneumonia virus (strain 15) (MPV) reference strain

FUS_MPV15 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Chicken/United States/B1/48) (NDV) reference strain

FUS_NDVB1 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Parainfluenza virus 5 (strain W3) (PIV5) (Simian virus 5) reference strain

FUS_PIV5 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 1SVF; 2B9B; 4GIP; 4WSG

1 entry

Rinderpest virus (strain RBOK) (RDV) reference strain

FUS_RINDR Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Sendai virus (strain Ohita) (SeV) reference strain

FUS_SENDO Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Simian virus 41 (SV41) reference strain

FUS_SV41 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Walleye dermal sarcoma virus (WDSV) reference strain

ENV_WDSV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein ...

1 entry

Xenotropic MuLV-related virus (isolate VP62) (XMRV) reference strain

ENV_XMRV6 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein ...

4 entries

Variola virus

Select_allDeselect_all
PG094_VARV Entry-fusion complex protein OPG094 (EFC protein OPG094) (Myristoylated protein G9)
PG099_VARV Entry-fusion complex protein OPG094 (EFC protein OPG094) (Protein L5)
PG086_VARV Entry-fusion complex protein OPG086 (EFC protein OPG086) (Protein G3)
H2_VARV Late protein H2

3 entries

Vaccinia virus (strain Ankara) (VACV)

Select_allDeselect_all
PG094_VACCA Entry-fusion complex protein OPG094 (EFC protein OPG094) (Myristoylated protein G9)
PG099_VACCA Entry-fusion complex protein OPG094 (EFC protein OPG094) (Protein L5)
J5_VACCA Protein J5

pdb 8WT5

2 entries

Epstein-Barr virus (strain GD1) (HHV-4) (Human gammaherpesvirus 4)

Select_allDeselect_all
GH_EBVG Envelope glycoprotein H (gH)

pdb 7D5Z; 8KHR

GL_EBVG Envelope glycoprotein L (gL)

pdb 7D5Z; 8KHR

2 entries

Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))

Select_allDeselect_all
GH_SUHVK Envelope glycoprotein H (gH)

pdb 2XQY

GL_SUHVK Envelope glycoprotein L (gL)

2 entries

Vaccinia virus (strain Tian Tan) (VACV)

Select_allDeselect_all
PG094_VACCT Entry-fusion complex protein OPG094 (EFC protein OPG094) (Myristoylated protein G9)
PG086_VACCT Entry-fusion complex protein OPG086 (EFC protein OPG086) (Protein G3)

2 entries

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Select_allDeselect_all
GH_VZVO Envelope glycoprotein H (gH)

pdb 4XHJ; 4XI5

GL_VZVO Envelope glycoprotein L (gL)

pdb 4XHJ; 4XI5

1 entry

AKV murine leukemia virus (AKR (endogenous) murine leukemia virus)

ENV_MLVAV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Avian reticuloendotheliosis virus

ENV_AVIRE Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 73) ...

1 entry

Avian spleen necrosis virus

ENV_AVISN Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 73) ...

1 entry

Baboon endogenous virus (strain M7)

ENV_BAEVM Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Bovine herpesvirus 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus)

GH_BHV1C Envelope glycoprotein H (gH)

1 entry

Bovine leukemia virus (BLV)

ENV_BLV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

pdb 2XZ3

1 entry

Bovine leukemia virus (isolate American FLK) (BLV)

ENV_BLVAF Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

1 entry

Bovine leukemia virus (isolate American VDM) (BLV)

ENV_BLVAV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

1 entry

Bovine leukemia virus (isolate Australian) (BLV)

ENV_BLVAU Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

1 entry

Bovine leukemia virus (isolate Belgium LB285) (BLV)

ENV_BLVB2 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

1 entry

Bovine leukemia virus (isolate Belgium LB59) (BLV)

ENV_BLVB5 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

1 entry

Bovine leukemia virus (isolate Japanese BLV-1) (BLV)

ENV_BLVJ Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 51) ...

1 entry

Bovine parainfluenza 3 virus (BPIV-3)

FUS_PI3B Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Bovine respiratory syncytial virus (strain Copenhagen) (BRS)

FUS_BRSVC Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

pdb 5TDL

1 entry

Bovine respiratory syncytial virus (strain Rb94) (BRS)

FUS_BRSVR Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

1 entry

Canine distemper virus (strain Onderstepoort) (CDV)

FUS_CDVO Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Cas-Br-E murine leukemia virus

ENV_MLVCB Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Elephantid herpesvirus 1 (isolate Asian elephant/Berlin/Kiba/1998) (EIHV-1) (Elephant endotheliotropic herpesvirus)

GH_ELHVK Envelope glycoprotein H (gH)

1 entry

Equine herpesvirus 1 (strain HVS25A) (EHV-1) (Equine abortion virus)

GH_EHV1 Envelope glycoprotein H (gH)

1 entry

Equine herpesvirus 1 (strain V592) (EHV-1) (Equine abortion virus)

GL_EHV1V Envelope glycoprotein L (gL)

1 entry

Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus)

GH_EHV4 Envelope glycoprotein H (gH)

1 entry

Feline endogenous virus ECE1

ENV_FENV1 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)

GH_FHV1 Envelope glycoprotein H (gH)

1 entry

Feline leukemia virus (isolate CFE-6)

ENV_FLVC6 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Feline leukemia virus (strain A/Glasgow-1)

ENV_FLVGL Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Feline leukemia virus (strain B/lambda-B1)

ENV_FLVLB Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

pdb 1LCS

1 entry

Feline leukemia virus (strain C/Sarma)

ENV_FLVSA Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Feline sarcoma virus (strain Gardner-Arnstein) (Ga-FeSV) (Gardner-Arnstein feline leukemia oncovirus B)

ENV_FSVGA Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Feline sarcoma virus (strain SM) (Sm-FeSV)

ENV_FSVSM Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Friend murine leukemia virus (isolate 57) (FrMLV)

ENV_MLVF5 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

pdb 1AOL

1 entry

Friend murine leukemia virus (isolate FB29) (FrMLV)

ENV_MLVFF Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Friend murine leukemia virus (isolate PVC-211) (FrMLV)

ENV_MLVFP Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Friend spleen focus-forming virus (isolate 502) (FSFFV)

ENV_FRSF5 Glycoprotein 55 (gp55)

1 entry

Friend spleen focus-forming virus (strain BB6) (FSFFV)

ENV_FRSFB Glycoprotein 42 (gp42)

1 entry

Friend spleen focus-forming virus (strain Lilly-Steeves) (FSFFV)

ENV_FRSFL Glycoprotein 55 (gp55)

1 entry

Gallid herpesvirus 2 (strain GA) (GaHV-2) (Marek's disease herpesvirus type 1)

GL_GAHVG Envelope glycoprotein L (gL)

1 entry

Gallid herpesvirus 2 (strain RB-1b) (GaHV-2) (Marek's disease herpesvirus type 1)

GH_GAHVR Envelope glycoprotein H (gH)

1 entry

Gibbon ape leukemia virus (GALV)

ENV_GALV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Hortulanus murine leukemia virus (HoMuLV) (Mus hortulanus virus)

ENV_MLVHO Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 76) ...

1 entry

Human T-cell leukemia virus 1 (isolate Caribbea CH subtype A) (HTLV-1)

ENV_HTL1N Envelope glycoprotein gp62 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 1 (isolate Melanesia mel5 subtype C) (HTLV-1)

ENV_HTL1L Envelope glycoprotein gp62 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 1 (isolate Zaire EL subtype B) (HTLV-1)

ENV_HTL1F Envelope glycoprotein gp62 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 1 (strain Japan MT-2 subtype A) (HTLV-1)

ENV_HTL1M Envelope glycoprotein gp62 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human T-cell leukemia virus 3 (strain Pyl43) (HTLV-3)

ENV_HTL3P Envelope glycoprotein gp63 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 46) ...

1 entry

Human cytomegalovirus (strain 1042) (HHV-5) (Human herpesvirus 5)

GL_HCMV2 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 119) (HHV-5) (Human herpesvirus 5)

GL_HCMV1 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 2387) (HHV-5) (Human herpesvirus 5)

GL_HCMV3 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 4654) (HHV-5) (Human herpesvirus 5)

GL_HCMV4 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 5035) (HHV-5) (Human herpesvirus 5)

GL_HCMV5 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 5040) (HHV-5) (Human herpesvirus 5)

GL_HCMV6 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 5160) (HHV-5) (Human herpesvirus 5)

GL_HCMV7 Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain 5508) (HHV-5) (Human herpesvirus 5)

GL_HCMV8 Envelope glycoprotein L (gL)

pdb 5VOB; 5VOC; 5VOD

1 entry

Human cytomegalovirus (strain PT) (HHV-5) (Human herpesvirus 5)

GL_HCMVP Envelope glycoprotein L (gL)

1 entry

Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)

GH_HCMVT Envelope glycoprotein H (gH)

1 entry

Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1)

GH_HHV1F Envelope glycoprotein H (gH)

1 entry

Human herpesvirus 1 (strain HFEM) (HHV-1) (Human herpes simplex virus 1)

GH_HHV1E Envelope glycoprotein H (gH)

1 entry

Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)

GL_HHV1K Envelope glycoprotein L (gL)

1 entry

Human herpesvirus 6A (strain GS) (HHV-6 variant A) (Human B lymphotropic virus)

GH_HHV6G Envelope glycoprotein H (gH)

1 entry

Human parainfluenza 1 virus (strain C39) (HPIV-1)

FUS_PI1HC Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Human parainfluenza 2 virus (HPIV-2)

FUS_PI2H Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Human parainfluenza 2 virus (strain Greer) (HPIV-2)

FUS_PI2HG Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Human parainfluenza 3 virus (strain Wash/47885/57) (HPIV-3) (Human parainfluenza 3 virus (strain NIH 47885))

FUS_PI3H4 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 1ZTM; 6NRO; 6NTX; 6NYX; 6O40; 6OJ7; 6PRL; 6PYQ; 6PZ6; 6V3V; 6VAS; 6VJO; 8DG8

1 entry

Human respiratory syncytial virus

FUS_HRSV Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

pdb 8T7A

1 entry

Human respiratory syncytial virus A (strain A2)

FUS_HRSVA Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

pdb 2MDP; 3IXT; 3KPE; 3O41; 3O45; 3RKI; 3RRR; 3RRT; 4CCF; 4JHW; 4MMQ; 4MMR; 4MMS; 4MMT; 4MMU; 4MMV; 4ZYP; 5C69; 5C6B; 5EA3; 5EA4; 5EA5; 5EA6; 5EA7; 5EA8; 5J3D; 5K6B; 5K6C; 5K6F; 5K6G; 5K6H; 5K6I; 5KWW; 5TOJ; 5TOK; 5TPN; 5U68; 5UDC; 5W23; 6APB; 6APD; 6CXC; 6DC3; 6DC5; 6EAD; 6EAE; 6EAF; 6EAG; 6EAH; 6EAI; 6EAJ; 6EAK; 6EAL; 6EAM; 6EAN; 6NTX; 6OE4; 6OE5; 6OJ7; 6OUS; 6VKC; 6VKD; 6VKE; 6W52; 7LUE; 7LVW; 7MMN; 7MPG; 7TN1; 8DG9; 8KG5; 8PHI; 8WSQ

1 entry

Human respiratory syncytial virus A (strain RSS-2)

FUS_HRSVR Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

pdb 1G2C

1 entry

Human respiratory syncytial virus B (strain 18537)

FUS_HRSV1 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2 (F2); p27 (Intervening segment) (Pep27) ...

pdb 6Q0S

1 entry

Koala retrovirus (KoRV)

ENV_KORV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)

ENV_MPMV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

pdb 4JF3

1 entry

Measles virus (strain Edmonston B) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASF Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Edmonston) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASE Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Edmonston-AIK-C vaccine) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASA Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Edmonston-Zagreb vaccine) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASZ Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Halle) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASH Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain IP-3-Ca) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASI Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Leningrad-16) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASL Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Philadelphia-26) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASP Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Measles virus (strain Yamagata-1) (MeV) (Subacute sclerose panencephalitis virus)

FUS_MEASY Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Meleagrid herpesvirus 1 (MeHV-1) (Turkey herpesvirus)

GH_MEHV1 Envelope glycoprotein H (gH)

1 entry

Mink cell focus-forming murine leukemia virus

ENV_MCFF Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Mink cell focus-forming murine leukemia virus (isolate CI-3)

ENV_MCFF3 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Mouse intracisternal a-particle MIAE (IAP-MIAE)

ENV_IPMAE Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein ...

1 entry

Mouse mammary tumor virus (strain GR) (MMTV)

ENV_MMTVG Envelope glycoprotein gp70 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 52) ...

1 entry

Mumps virus (strain RW) (MuV)

FUS_MUMPR Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Mumps virus (strain SBL) (MuV)

FUS_MUMPS Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Mumps virus (strain SBL-1) (MuV)

FUS_MUMP1 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Murid herpesvirus 1 (strain K181) (MuHV-1) (Mouse cytomegalovirus)

GL_MUHVK Envelope glycoprotein L (gL)

1 entry

Myeloproliferative leukemia virus (MpLV)

ENV_MPLV Envelope glycoprotein (Env polyprotein)

1 entry

Newcastle disease virus (strain B1-Hitchner/47) (NDV)

FUS_NDVH4 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Beaudette C/45) (NDV)

FUS_NDVB Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Chicken/Australia-Victoria/32) (NDV)

FUS_NDVA Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 3MAW

1 entry

Newcastle disease virus (strain Chicken/Northern Ireland/Ulster/67) (NDV)

FUS_NDVU Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Chicken/United States(TX)/GB/48) (NDV) (Newcastle disease virus (strain Texas g.b./48))

FUS_NDVTG Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Chicken/United States/LaSota/46) (NDV)

FUS_NDVL Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain D26/76) (NDV)

FUS_NDVD Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 1G5G

1 entry

Newcastle disease virus (strain Her/33) (NDV)

FUS_NDVH3 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Italien/45) (NDV)

FUS_NDVI Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Miyadera/51) (NDV)

FUS_NDVM Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Queensland/66) (NDV)

FUS_NDVQ Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Newcastle disease virus (strain Texas) (NDV)

FUS_NDVT Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Nipah virus

FUS_NIPAV Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

pdb 1WP7; 3N27; 5EVM; 6T3F; 6TYS; 7KI4; 7UOP; 7UP9; 7UPA; 7UPB; 7UPD; 7UPK; 8DMJ; 8DNG; 8DO4; 8RVN; 8XN9; 8XNH

1 entry

Phocine distemper virus (PDV)

FUS_PHODV Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Radiation murine leukemia virus

ENV_MLVRD Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 76) ...

1 entry

Radiation murine leukemia virus (strain Kaplan)

ENV_MLVRK Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 76) ...

1 entry

Rauscher mink cell focus-inducing virus

ENV_RMCFV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Rauscher spleen focus-forming virus (RSFFV)

ENV_RSFFV Glycoprotein 55 (gp55)

1 entry

Rinderpest virus (strain Kabete O) (RDV)

FUS_RINDK Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Rinderpest virus (strain L) (RDV)

FUS_RINDL Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Rinderpest virus (strain RBT1) (RDV)

FUS_RINDB Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Rous sarcoma virus subgroup B (strain Schmidt-Ruppin) (RSV-SR-B)

ENV_RSVSB Envelope glycoprotein gp95 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 85) ...

1 entry

Rous sarcoma virus subgroup C (strain Prague) (RSV-Pr-C)

ENV_RSVP Envelope glycoprotein gp95 (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 85) ...

1 entry

Sendai virus (strain Fushimi) (SeV)

FUS_SENDF Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Sendai virus (strain Hamamatsu) (SeV)

FUS_SENDA Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Sendai virus (strain Harris) (SeV)

FUS_SENDH Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Sendai virus (strain Z) (SeV) (Sendai virus (strain HVJ))

FUS_SENDZ Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Sheep pulmonary adenomatosis virus (Jaagsiekte sheep retrovirus) (JSRV)

ENV_JSRV Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 52) ...

1 entry

Simian retrovirus SRV-1

ENV_SRV1 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Simian retrovirus SRV-2

ENV_SRV2 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Simian retrovirus SRV-2 (isolate 2R-18B1)

ENV_SRV2R Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Squirrel monkey retrovirus (SMRV-H) (SMRV-HLB)

ENV_SMRVH Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) ...

1 entry

Suid herpesvirus 1 (strain Indiana-Funkhauser / Becker) (SuHV-1) (Pseudorabies virus (strain Indiana-Funkhauser / Becker))

GL_SUHVF Envelope glycoprotein L (gL)

1 entry

Suid herpesvirus 1 (strain NIA-3) (SuHV-1) (Pseudorabies virus (strain NIA-3))

GH_SUHVN Envelope glycoprotein H (gH)

1 entry

Suid herpesvirus 1 (strain Rice) (SuHV-1) (Pseudorabies virus (strain Rice))

GH_SUHVR Envelope glycoprotein H (gH)

1 entry

Turkey rhinotracheitis virus (TRTV)

FUS_TRTV Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2; Fusion glycoprotein F1]

1 entry

Xenotropic MuLV-related virus (isolate VP35) (XMRV)

ENV_XMRV3 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein ...

1 entry

Xenotropic MuLV-related virus (isolate VP42) (XMRV)

ENV_XMRV4 Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein ...