Picovirinae (taxid:542836)

VIRION

Non-enveloped, head-tail structure. Head is about 54 nm in diameter. The tail is non-contractile and has a collar with 12 appendages. The capsid is icosahedral with a T=3 symmetry.

GENOME

Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes.

GENE EXPRESSION

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to the target cell via its tail fibers.
  2. Ejection by short tail system: viral DNA is injected into the periplams of the host cell.
  3. Transcription and translation of the early genes
  4. Replication of genomic DNA by Strand displacement by viral DNA polymerase, formation of viral genome concatemers.
  5. Transcription and translation of late genes
  6. Assembly of empty procapsids and viral genome packaging.
  7. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

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