Cavemovirus

VIRION

image

Non enveloped, large (50 nm diameter) icosahedral particles composed of 420 subunits T=7 symmetry. It has not been described whether handedness of capsid is laevo or dextro, here the pictures dsplays a laevo form.

GENOME

image

Monopartite, open circular, double stranded DNA of about 8000 base pairs with discontinuities in both strands: one in the transcribed strand and one to three in the non-transcribed strand. Codes for 5 proteins.

GENE EXPRESSION



Enzymes: Aspartic protease, Reverse-transcriptase, RNAse H

REPLICATION

CYTOPLASMIC / NUCLEAR

  1. Attachment of viral proteins to host receptors mediates entry into the host cell.
  2. The viral dsDNA is released into the nucleus.
  3. Transcribed by host RNA polymerase II.
  4. mRNA translation produces viral proteins.
  5. Genomic RNA is retrotranscribed into new dsDNA genomes in the cytoplasm.
  6. Genomes are encapsidated by the capsid protein and form new virions.
  7. The virion infects either a new cell by plasmodesmata movement, or by insect vector uptake.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

5 entries grouped by protein (browse by keywords)

1 entry

Putative Polyprotein CP

CP_CSVMV
Cassava vein mosaic virus (CsVMV) reference strain

1 entry

Putative transactivator/viroplasmin protein (Tav) (Inclusion body matrix protein)

IBMP_CSVMV
Cassava vein mosaic virus (CsVMV) reference strain

1 entry

Putative enzymatic polyprotein

POL_CSVMV
Cassava vein mosaic virus (CsVMV) reference strain

1 entry

Uncharacterized 6 kDa protein

YP06_CSVMV
Cassava vein mosaic virus (CsVMV) reference strain

1 entry

Uncharacterized 9 kDa protein

YP09_CSVMV
Cassava vein mosaic virus (CsVMV) reference strain