Tectiviridae

VIRION

Non enveloped, icosahedral virion with a pseudo T=25 symmetry. Virion size is about 66 nm with apical spikes of 20 nm. The capsid encloses a inner membrane vesicle within which the genomic DNA is coiled.

GENOME

Linear, dsDNA genome of about 15 kb flanked by inverted repeats. Encodes for 30 ORFs. Replication is protein-primed.

GENE EXPRESSION

Genes are transcribed by operons.

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its spike protein P2. As a result, a protein complex composed of P2, P5, P31 and a part of the capsid (p3) is released, which produces a hole in the capsid.
  2. Internal phage membrane transforms into a tubular structure that protrudes through the hole in the capsid and penetrates the host outer membrane and peptidoglycan layer, to fuse with host plasma membrane, releasing the viral DNA into cytoplasm.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA.
  5. Transcription and translation of late genes.
  6. Capsid proteins polymerize around a lipoprotein vesicle translocated in the cytoplasm by virion assembly factors.
  7. Genomic DNA is packaged in new virions.
  8. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

26 entries grouped by protein (browse by keywords)

1 entry

Major capsid protein P3 (Protein P3)

CAPSD_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Protein P1)

DPOL_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Endolysin (EC 3.2.1.17) (Beta-1,4-N-acetylmuramidase) (Lysozyme) (Lytic enzyme) (Muramidase) (Protein P15)

ENLYS_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Transglycosylase (EC 4.2.2.n1) (Protein P7)

EXLYS_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Holin (Protein P35)

HOLIN_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Adsorption protein P2 (Protein P2)

P2_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Spike protein P5 (Protein P5)

P5_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Packaging protein P20

PKG20_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Packaging protein P22 (GpK) (Protein K)

PKG22_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Packaging efficiency factor P6

PKG6_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

DNA packaging ATPase P9 (Protein P9)

PKG9_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

2 entries

DNA terminal protein

Select_allDeselect_all
TERM_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

DNA terminal protein (Protein P8)

TERM_BP35C
Bacillus phage Bam35c (Bacillus thuringiensis bacteriophage Bam35c)

1 entry

Protein P10

VP10_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Infectivity protein P11

VP11_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Single-stranded DNA-binding protein (Protein P12)

VP12_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P16 (GpS) (Protein S)

VP16_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P17

VP17_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P18 (GpM) (Protein M)

VP18_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P19

VP19_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Minor capsid protein P30 (Protein P) (GpP)

VP30_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Penton protein P31 (GpC) (Protein C)

VP31_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P32

VP32_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P33

VP33_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Protein P34 (Protein O) (GpO)

VP34_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

1 entry

Putative uncharacterized 4.5 kDa protein in genes IX-XX intergenic region (ORFi)

YPI_BPPRD
Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain