Unknown Taxon 11989

VIRION

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Non-enveloped, spherical virion about 26 nm in diameter with T=3 icosahedral symmetry composed of 178 CP proteins and a single A maturation protein .
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GENOME

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Monopartite, linear, ssRNA(+) genome about 3.4-4.3 kb in size. The 5' end is a triphosphate. Encodes 3 (Allelovirus) or 4 proteins (Levivirus).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. Encodes 4 ORFs. Cp protein represses replicase translation by binding a RNA hairpin at the start site of this gene.
Lysis protein is expressed by suppression of termination of an UGA nonsense codon in Allolevivirus genus.

REPLICATION

  1. Adsorption to F pili of target cells induces cleavage and release of the maturation protein.
  2. Genomic RNA enters the bacterium.
  3. Viral proteins are translated.
  4. Viral replicase assembles with host proteins (ribosomal protein S1, translation elongation factors EF-Tu and EF-Ts) to form the active RNA polymerase.
  5. Replication of genomic RNA into a minus strand, which serves as template to produce new positive strand genomes.
  6. Late in infection CP protein bind to a RNA hairpin on the genome, and new virus particles are assembled in the cytoplasm.
  7. Release by cell lysis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

21 entries grouped by protein (browse by keywords)

2 entries

Minor capsid protein A1

Select_allDeselect_all
A1_BPQBE
Escherichia virus Qbeta (Bacteriophage Q-beta) reference strain

Minor capsid protein A1 (A1 read-through protein)

A1_BPSP
Enterobacteria phage SP (Bacteriophage SP) reference strain

8 entries

Capsid protein (CP) (Coat protein)

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CAPSD_BPFR
Enterobacteria phage fr (Bacteriophage fr) reference strain
CAPSD_BPMS2
Escherichia phage MS2 (Bacteriophage MS2) reference strain
CAPSD_BPQBE
Escherichia virus Qbeta (Bacteriophage Q-beta) reference strain
CAPSD_BPSP
Enterobacteria phage SP (Bacteriophage SP) reference strain
CAPSD_BPF2
Enterobacteria phage f2 (Bacteriophage f2)
CAPSD_BPJP3
Enterobacteria phage JP34 (Bacteriophage JP34)
CAPSD_BPR17
Enterobacteria phage R17 (Bacteriophage R17)
CAPSD_BPZR
Enterobacteria phage ZR (Bacteriophage ZR)

3 entries

Lysis protein

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LYS_BPFR
Enterobacteria phage fr (Bacteriophage fr) reference strain
LYS_BPMS2
Escherichia phage MS2 (Bacteriophage MS2) reference strain

Lysis protein (L protein)

LYS_BPJP3
Enterobacteria phage JP34 (Bacteriophage JP34)

2 entries

Maturation protein A (MP) (Assembly protein) (A protein)

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MATA_BPFR
Enterobacteria phage fr (Bacteriophage fr) reference strain
MATA_BPMS2
Escherichia phage MS2 (Bacteriophage MS2) reference strain

2 entries

Maturation protein A2 (MP) (A2 protein)

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MATA2_BPQBE
Escherichia virus Qbeta (Bacteriophage Q-beta) reference strain
MATA2_BPSP
Enterobacteria phage SP (Bacteriophage SP) reference strain

Maturation protein A2 (MP) (A2) (Assembly protein) (A protein)

4 entries

RNA-directed RNA polymerase beta chain (EC 2.7.7.48) (RNA replicase beta chain)

Select_allDeselect_all
RDRP_BPFR
Enterobacteria phage fr (Bacteriophage fr) reference strain
RDRP_BPMS2
Escherichia phage MS2 (Bacteriophage MS2) reference strain
RDRP_BPQBE
Escherichia virus Qbeta (Bacteriophage Q-beta) reference strain

RNA-directed RNA polymerase subunit beta (EC 2.7.7.48) (RNA replicase beta chain) (RNA-directed RNA polymerase subunit II)

RDRP_BPSP
Enterobacteria phage SP (Bacteriophage SP) reference strain

RNA-directed RNA polymerase subunit beta (EC 2.7.7.48) (RNA replicase beta chain)