DNA strand displacement replication
Related to: Adenoviridae, Asfarviridae, Iridoviridae, Mimiviridae(?), Phycodnaviridae(?), Poxviridae, Tectiviridae, Phi29likevirus.
Location: In host cell nucleus (Adenoviridae) or cytoplasm (Nucleo-Cytoplasmic Large DNA viruses).
Replication events: In strand-displacement replication, only one strand is replicated at once. This synthesis releases a single stranded DNA, which is in turn copied into double strand-DNA. Adenoviridae replication is primed by a pre-Terminal Protein (pTP), Nucleo-cytoplasmic Large DNA viruses replication is primed by a repeated loop at genomic extremities and produces concatemers that are processed post-replication.